The pancreatic β cell: recent insights from human genetics

por Thomsen, Soren K., Gloyn, Anna L.
Publicado 2014

Genome-edited human stem cell-derived beta cells: a powerful tool for drilling down on type 2 diabetes GWAS biology

por Beer, Nicola L., Gloyn, Anna L.
Publicado 2016

Human genetics as a model for target validation: finding new therapies for diabetes

por Thomsen, Soren K., Gloyn, Anna L.
Publicado 2017

Type 2 Diabetes Susceptibility Gene TCF7L2 and Its Role in β-Cell Function

por Gloyn, Anna L., Braun, Matthias, Rorsman, Patrik
Publicado 2009

Insights into metabolic disease from studying genetics in isolated populations: stories from Greece to Greenland

por Zeggini, Eleftheria, Gloyn, Anna L., Hansen, Torben
Publicado 2016

Species-Specific Differences in the Expression of the HNF1A, HNF1B and HNF4A Genes

por Harries, Lorna W., Brown, James E., Gloyn, Anna L.
Publicado 2009

Prioritising Causal Genes at Type 2 Diabetes Risk Loci

por Grotz, Antje K., Gloyn, Anna L., Thomsen, Soren K.
Publicado 2017

The Importance of Context: Uncovering Species- and Tissue-Specific Effects of Genetic Risk Variants for Type 2 Diabetes

por Thomsen, Soren K., McCarthy, Mark I., Gloyn, Anna L.
Publicado 2016

Management of Neonatal Diabetes due to a KCNJ11 Mutation with Automated Insulin Delivery System and Remote Patient Monitoring

por Lee, Ming Yeh, Gloyn, Anna L., Maahs, David M., Prahalad, Priya
Publicado 2023

Response to Comment on: McDonald et al. High-Sensitivity CRP Discriminates HNF1A-MODY From Other Subtypes of Diabetes. Diabetes Care 2011;34:1860–1862

por McDonald, Tim J., Owen, Katharine R., Gloyn, Anna L., Hattersley, Andrew T.
Publicado 2011

Gene duplications resulting in over expression of glucokinase are not a common cause of hypoglycaemia of infancy in humans

por van de Bunt, Martijn, Edghill, Emma L., Hussain, Khalid, Ellard, Sian, Gloyn, Anna L.
Publicado 2008

A CRISPR/Cas9 genome editing pipeline in the EndoC-βH1 cell line to study genes implicated in beta cell function

por Grotz, Antje K., Abaitua, Fernando, Navarro-Guerrero, Elena, Hastoy, Benoit, Ebner, Daniel, Gloyn, Anna L.
Publicado 2020

Analysis of the co-operative interaction between the allosterically regulated proteins GK and GKRP using tryptophan fluorescence

por Zelent, Bogumil, Raimondo, Anne, Barrett, Amy, Buettger, Carol W., Chen, Pan, Gloyn, Anna L., Matschinsky, Franz M.
Publicado 2014

Safe use of the ketogenic diet in an infant with microcephaly, epilepsy, and diabetes syndrome: a case report

por Zegarra, Walter A., Gallentine, William B., Ruzhnikov, Maura R., McAndrews, Catherine A., Gloyn, Anna L., Addala, Ananta
Publicado 2023

Multiplexed CRISPR gene editing in primary human islet cells with Cas9 ribonucleoprotein

por Bevacqua, Romina J., Zhao, Weichen, Merheb, Emilio, Kim, Seung Hyun, Marson, Alexander, Gloyn, Anna L., Kim, Seung K.
Publicado 2023

Coexpression of the Type 2 Diabetes Susceptibility Gene Variants KCNJ11 E23K and ABCC8 S1369A Alter the ATP and Sulfonylurea Sensitivities of the ATP-Sensitive K(+) Channel

por Hamming, Kevin S.C., Soliman, Daniel, Matemisz, Laura C., Niazi, Omid, Lang, Yiqiao, Gloyn, Anna L., Light, Peter E.
Publicado 2009

High-Sensitivity CRP Discriminates HNF1A-MODY From Other Subtypes of Diabetes

por McDonald, Tim J., Shields, Beverley M., Lawry, Jane, Owen, Katharine R., Gloyn, Anna L., Ellard, Sian, Hattersley, Andrew T.
Publicado 2011

Assessment of High-Sensitivity C-Reactive Protein Levels as Diagnostic Discriminator of Maturity-Onset Diabetes of the Young Due to HNF1A Mutations

por Owen, Katharine R., Thanabalasingham, Gaya, James, Timothy J., Karpe, Fredrik, Farmer, Andrew J., McCarthy, Mark I., Gloyn, Anna L.
Publicado 2010

Low Frequency Variants in the Exons Only Encoding Isoform A of HNF1A Do Not Contribute to Susceptibility to Type 2 Diabetes

por Jafar-Mohammadi, Bahram, Groves, Christopher J., Owen, Katharine R., Frayling, Timothy M., Hattersley, Andrew T., McCarthy, Mark I., Gloyn, Anna L.
Publicado 2009

A Panel of Diverse Assays to Interrogate the Interaction between Glucokinase and Glucokinase Regulatory Protein, Two Vital Proteins in Human Disease

por Rees, Matthew G., Davis, Mindy I., Shen, Min, Titus, Steve, Raimondo, Anne, Barrett, Amy, Gloyn, Anna L., Collins, Francis S., Simeonov, Anton
Publicado 2014