Use of Mutated Self-Cleaving 2A Peptides as a Molecular Rheostat to Direct Simultaneous Formation of Membrane and Secreted Anti-HIV Immunoglobulins

por Yu, Kenneth K., Aguilar, Kiefer, Tsai, Jonathan, Galimidi, Rachel, Gnanapragasam, Priyanthi, Yang, Lili, Baltimore, David
Publicado 2012

Electron tomography visualization of HIV-1 fusion with target cells using fusion inhibitors to trap the pre-hairpin intermediate

por Ladinsky, Mark S, Gnanapragasam, Priyanthi NP, Yang, Zhi, West, Anthony P, Kay, Michael S, Bjorkman, Pamela J
Publicado 2020

Construction, characterization, and immunization of nanoparticles that display a diverse array of influenza HA trimers

por Cohen, Alexander A., Yang, Zhi, Gnanapragasam, Priyanthi N. P., Ou, Susan, Dam, Kim-Marie A., Wang, Haoqing, Bjorkman, Pamela J.
Publicado 2021

HIV-1 CD4-binding site germline antibody–Env structures inform vaccine design

por Dam, Kim-Marie A., Barnes, Christopher O., Gristick, Harry B., Schoofs, Till, Gnanapragasam, Priyanthi N. P., Nussenzweig, Michel C., Bjorkman, Pamela J.
Publicado 2022

Nanoparticles presenting clusters of CD4 expose a universal vulnerability of HIV-1 by mimicking target cells

por Hoffmann, Magnus A. G., Bar-On, Yotam, Yang, Zhi, Gristick, Harry B., Gnanapragasam, Priyanthi N. P., Vielmetter, Jost, Nussenzweig, Michel C., Bjorkman, Pamela J.
Publicado 2020

Antibody elicited by HIV-1 immunogen vaccination in macaques displaces Env fusion peptide and destroys a neutralizing epitope

por Abernathy, Morgan E., Gristick, Harry B., Vielmetter, Jost, Keeffe, Jennifer R., Gnanapragasam, Priyanthi N. P., Lee, Yu E., Escolano, Amelia, Gautam, Rajeev, Seaman, Michael S., Martin, Malcolm A., Nussenzweig, Michel C., Bjorkman, Pamela J.
Publicado 2021

ESCRT recruitment to mRNA-encoded SARS-CoV-2 spike induces virus-like particles and enhanced antibody responses

por Hoffmann, Magnus A. G., Yang, Zhi, Huey-Tubman, Kathryn E., Cohen, Alexander A., Gnanapragasam, Priyanthi N. P., Nakatomi, Leesa M., Storm, Kaya N., Moon, Woohyun J., Lin, Paulo J.C., Bjorkman, Pamela J.
Publicado 2022

ESCRT recruitment to SARS-CoV-2 spike induces virus-like particles that improve mRNA vaccines

por Hoffmann, Magnus A.G., Yang, Zhi, Huey-Tubman, Kathryn E., Cohen, Alexander A., Gnanapragasam, Priyanthi N.P., Nakatomi, Leesa M., Storm, Kaya N., Moon, Woohyun J., Lin, Paulo J.C., West, Anthony P., Bjorkman, Pamela J.
Publicado 2023

Rapid identification of neutralizing antibodies against SARS-CoV-2 variants by mRNA display

por Tanaka, Shiho, Olson, C. Anders, Barnes, Christopher O., Higashide, Wendy, Gonzalez, Marcos, Taft, Justin, Richardson, Ashley, Martin-Fernandez, Marta, Bogunovic, Dusan, Gnanapragasam, Priyanthi N.P., Bjorkman, Pamela J., Spilman, Patricia, Niazi, Kayvan, Rabizadeh, Shahrooz, Soon-Shiong, Patrick
Publicado 2022

Mosaic nanoparticles elicit cross-reactive immune responses to zoonotic coronaviruses in mice

por Cohen, Alexander A., Gnanapragasam, Priyanthi N.P., Lee, Yu E., Hoffman, Pauline R., Ou, Susan, Kakutani, Leesa M., Keeffe, Jennifer R., Wu, Hung-Jen, Howarth, Mark, West, Anthony P., Barnes, Christopher O., Nussenzweig, Michel C., Bjorkman, Pamela J.
Publicado 2021

Mosaic nanoparticles elicit cross-reactive immune responses to zoonotic coronaviruses in mice

por Cohen, Alexander A., Gnanapragasam, Priyanthi N. P., Lee, Yu E., Hoffman, Pauline R., Ou, Susan, Kakutani, Leesa M., Keeffe, Jennifer R., Wu, Hung-Jen, Howarth, Mark, West, Anthony P., Barnes, Christopher O., Nussenzweig, Michel C., Bjorkman, Pamela J.
Publicado 2021

Neutralizing monoclonal antibodies elicited by mosaic RBD nanoparticles bind conserved sarbecovirus epitopes

por Fan, Chengcheng, Cohen, Alexander A., Park, Miso, Hung, Alfur Fu-Hsin, Keeffe, Jennifer R., Gnanapragasam, Priyanthi N.P., Lee, Yu E., Gao, Han, Kakutani, Leesa M., Wu, Ziyan, Kleanthous, Harry, Malecek, Kathryn E., Williams, John C., Bjorkman, Pamela J.
Publicado 2022

Broad cross-reactivity across sarbecoviruses exhibited by a subset of COVID-19 donor-derived neutralizing antibodies

por Jette, Claudia A., Cohen, Alexander A., Gnanapragasam, Priyanthi N.P., Muecksch, Frauke, Lee, Yu E., Huey-Tubman, Kathryn E., Schmidt, Fabian, Hatziioannou, Theodora, Bieniasz, Paul D., Nussenzweig, Michel C., West, Anthony P., Keeffe, Jennifer R., Bjorkman, Pamela J., Barnes, Christopher O.
Publicado 2021

Broad cross-reactivity across sarbecoviruses exhibited by a subset of COVID-19 donor-derived neutralizing antibodies

por Jette, Claudia A., Cohen, Alexander A., Gnanapragasam, Priyanthi N.P., Muecksch, Frauke, Lee, Yu E., Huey-Tubman, Kathryn E., Schmidt, Fabian, Hatziioannou, Theodora, Bieniasz, Paul D., Nussenzweig, Michel C., West, Anthony P., Keeffe, Jennifer R., Bjorkman, Pamela J., Barnes, Christopher O.
Publicado 2021

Broad cross-reactivity across sarbecoviruses exhibited by a subset of COVID-19 donor-derived neutralizing antibodies

por Jette, Claudia A., Cohen, Alexander A., Gnanapragasam, Priyanthi N.P., Muecksch, Frauke, Lee, Yu E., Huey-Tubman, Kathryn E., Schmidt, Fabian, Hatziioannou, Theodora, Bieniasz, Paul D., Nussenzweig, Michel C., West, Anthony P., Keeffe, Jennifer R., Bjorkman, Pamela J., Barnes, Christopher O.
Publicado 2021

Multiviral Quartet Nanocages Elicit Broad Anti-Coronavirus Responses for Proactive Vaccinology

por Hills, Rory A., Kit Tan, Tiong, Cohen, Alexander A., Keeffe, Jennifer R., Keeble, Anthony H., Gnanapragasam, Priyanthi N.P., Storm, Kaya N., Hill, Michelle L., Liu, Sai, Gilbert-Jaramillo, Javier, Afzal, Madeeha, Napier, Amy, James, William S., Bjorkman, Pamela J., Townsend, Alain R., Howarth, Mark
Publicado 2023

A naturally arising broad and potent CD4-binding site antibody with low somatic mutation

por Barnes, Christopher O., Schoofs, Till, Gnanapragasam, Priyanthi N.P., Golijanin, Jovana, Huey-Tubman, Kathryn E., Gruell, Henning, Schommers, Philipp, Suh-Toma, Nina, Lee, Yu Erica, Cetrulo Lorenzi, Julio C., Piechocka-Trocha, Alicja, Scheid, Johannes F., West, Anthony P., Walker, Bruce D., Seaman, Michael S., Klein, Florian, Nussenzweig, Michel C., Bjorkman, Pamela J.
Publicado 2022

Detection and characterization of the SARS-CoV-2 lineage B.1.526 in New York

por West, Anthony P., Wertheim, Joel O., Wang, Jade C., Vasylyeva, Tetyana I., Havens, Jennifer L., Chowdhury, Moinuddin A., Gonzalez, Edimarlyn, Fang, Courtney E., Di Lonardo, Steve S., Hughes, Scott, Rakeman, Jennifer L., Lee, Henry H., Barnes, Christopher O., Gnanapragasam, Priyanthi N. P., Yang, Zhi, Gaebler, Christian, Caskey, Marina, Nussenzweig, Michel C., Keeffe, Jennifer R., Bjorkman, Pamela J.
Publicado 2021

Detection and characterization of the SARS-CoV-2 lineage B.1.526 in New York

por West, Anthony P., Wertheim, Joel O., Wang, Jade C., Vasylyeva, Tetyana I., Havens, Jennifer L., Chowdhury, Moinuddin A., Gonzalez, Edimarlyn, Fang, Courtney E., Di Lonardo, Steve S., Hughes, Scott, Rakeman, Jennifer L., Lee, Henry H., Barnes, Christopher O., Gnanapragasam, Priyanthi N. P., Yang, Zhi, Gaebler, Christian, Caskey, Marina, Nussenzweig, Michel C., Keeffe, Jennifer R., Bjorkman, Pamela J.
Publicado 2021

Mosaic RBD nanoparticles protect against multiple sarbecovirus challenges in animal models

por Cohen, Alexander A., van Doremalen, Neeltje, Greaney, Allison J., Andersen, Hanne, Sharma, Ankur, Starr, Tyler N., Keeffe, Jennifer R., Fan, Chengcheng, Schulz, Jonathan E., Gnanapragasam, Priyanthi N.P., Kakutani, Leesa M., West, Anthony P., Saturday, Greg, Lee, Yu E., Gao, Han, Jette, Claudia A., Lewis, Mark G., Tan, Tiong K., Townsend, Alain R., Bloom, Jesse D., Munster, Vincent J., Bjorkman, Pamela J.
Publicado 2022