The endothelin receptor antagonist macitentan for the treatment of pulmonary arterial hypertension: A cross‐species comparison of its cytochrome P450 induction pattern

por Treiber, Alexander, Delahaye, Stephane, Seeland, Swen, Gnerre, Carmela
Publicado 2020

The evolution of drug-activated nuclear receptors: one ancestral gene diverged into two xenosensor genes in mammals

por Handschin, Christoph, Blättler, Sharon, Roth, Adrian, Looser, Renate, Oscarson, Mikael, Kaufmann, Michel R, Podvinec, Michael, Gnerre, Carmela, Meyer, Urs A
Publicado 2004

Absorption, Metabolism, and Excretion of ACT-1004-1239, a First-In-Class CXCR7 Antagonist: In Vitro, Preclinical, and Clinical Data

por Huynh, Christine, Seeland, Swen, Segrestaa, Jerome, Gnerre, Carmela, Hogeback, Jens, Meyer zu Schwabedissen, Henriette E., Dingemanse, Jasper, Sidharta, Patricia N.
Publicado 2022