Design, Synthesis, Docking, DFT, MD Simulation Studies of a New Nicotinamide-Based Derivative: In Vitro Anticancer and VEGFR-2 Inhibitory Effects

por Elkaeed, Eslam B., Yousef, Reda G., Elkady, Hazem, Gobaara, Ibraheem M. M., Alsfouk, Bshra A., Husein, Dalal Z., Ibrahim, Ibrahim M., Metwaly, Ahmed M., Eissa, Ibrahim H.
Publicado 2022

(E)-N-(3-(1-(2-(4-(2,2,2-Trifluoroacetamido)benzoyl)hydrazono)ethyl)phenyl)nicotinamide: A Novel Pyridine Derivative for Inhibiting Vascular Endothelial Growth Factor Receptor-2: S...

por Yousef, Reda G., Elkady, Hazem, Elkaeed, Eslam B., Gobaara, Ibraheem M. M., Al-ghulikah, Hanan A., Husein, Dalal Z., Ibrahim, Ibrahim M., Metwaly, Ahmed M., Eissa, Ibrahim H.
Publicado 2022

Design, Synthesis, In Silico and In Vitro Studies of New Immunomodulatory Anticancer Nicotinamide Derivatives Targeting VEGFR-2

por Yousef, Reda G., Eldehna, Wagdy M., Elwan, Alaa, Abdelaziz, Abdelaziz S., Mehany, Ahmed B. M., Gobaara, Ibraheem M. M., Alsfouk, Bshra A., Elkaeed, Eslam B., Metwaly, Ahmed M., Eissa, Ibrahim H.
Publicado 2022

Discovery of new nicotinamides as apoptotic VEGFR-2 inhibitors: virtual screening, synthesis, anti-proliferative, immunomodulatory, ADMET, toxicity, and molecular dynamic simulatio...

por Yousef, Reda G., Ibrahim, Albaraa, Khalifa, Mohamed M., Eldehna, Wagdy M., Gobaara, Ibraheem M. M., Mehany, Ahmed B. M., Elkaeed, Eslam B., Alsfouk, Aisha A., Metwaly, Ahmed M., Eissa, Ibrahim H.
Publicado 2022

Anti-cancer and immunomodulatory evaluation of new nicotinamide derivatives as potential VEGFR-2 inhibitors and apoptosis inducers: in vitro and in silico studies

por Yousef, Reda G., Elwan, Alaa, Gobaara, Ibraheem M. M., Mehany, Ahmed B. M., Eldehna, Wagdy M., El-Metwally, Souad A., A. Alsfouk, Bshra, Elkaeed, Eslam B., Metwaly, Ahmed M., Eissa, Ibrahim H.
Publicado 2022

Discovery of New VEGFR-2 Inhibitors: Design, Synthesis, Anti-Proliferative Evaluation, Docking, and MD Simulation Studies

por Elkaeed, Eslam B., Yousef, Reda G., Khalifa, Mohamed M., Ibrahim, Albaraa, Mehany, Ahmed B. M., Gobaara, Ibraheem M. M., Alsfouk, Bshra A., Eldehna, Wagdy M., Metwaly, Ahmed M., Eissa, Ibrahim H., El-Zahabi, Mohamed Ayman
Publicado 2022