Viewing AML through a New Lens: Technological Advances in the Study of Epigenetic Regulation

por Godfrey, Laura C., Rodriguez-Meira, Alba
Publicado 2022

Redesign of a brief PTSD treatment in safety net integrated primary care: Supporting implementation in the context of the COVID-19 pandemic

por Valentine, Sarah E., Fuchs, Cara, Godfrey, Laura, Elwy, A. Rani
Publicado 2022

Formative evaluation prior to implementation of a brief treatment for posttraumatic stress disorder in primary care

por Valentine, Sarah E., Fuchs, Cara, Olesinski, Elyse A., Sarkisova, Natalya, Godfrey, Laura B., Elwy, A. Rani
Publicado 2023

wuHMM: a robust algorithm to detect DNA copy number variation using long oligonucleotide microarray data

por Cahan, Patrick, Godfrey, Laura E., Eis, Peggy S., Richmond, Todd A., Selzer, Rebecca R., Brent, Michael, McLeod, Howard L., Ley, Timothy J., Graubert, Timothy A.
Publicado 2008

MLL-AF4 binds directly to a BCL-2 specific enhancer and modulates H3K27 acetylation

por Godfrey, Laura, Kerry, Jon, Thorne, Ross, Repapi, Emmanouela, Davies, James O.J., Tapia, Marta, Ballabio, Erica, Hughes, Jim R., Geng, Huimin, Konopleva, Marina, Milne, Thomas A.
Publicado 2017

BET inhibition disrupts transcription but retains enhancer-promoter contact

por Crump, Nicholas T., Ballabio, Erica, Godfrey, Laura, Thorne, Ross, Repapi, Emmanouela, Kerry, Jon, Tapia, Marta, Hua, Peng, Lagerholm, Christoffer, Filippakopoulos, Panagis, Davies, James O. J., Milne, Thomas A.
Publicado 2021

ITIH5 and ECRG4 DNA Methylation Biomarker Test (EI-BLA) for Urine-Based Non-Invasive Detection of Bladder Cancer

por Rose, Michael, Bringezu, Sarah, Godfrey, Laura, Fiedler, David, Gaisa, Nadine T., Koch, Maximilian, Bach, Christian, Füssel, Susanne, Herr, Alexander, Hübner, Doreen, Ellinger, Jörg, Pfister, David, Knüchel, Ruth, Wirth, Manfred P., Böhme, Manja, Dahl, Edgar
Publicado 2020

MLL-AF4 Spreading Identifies Binding Sites that Are Distinct from Super-Enhancers and that Govern Sensitivity to DOT1L Inhibition in Leukemia

por Kerry, Jon, Godfrey, Laura, Repapi, Emmanouela, Tapia, Marta, Blackledge, Neil P., Ma, Helen, Ballabio, Erica, O’Byrne, Sorcha, Ponthan, Frida, Heidenreich, Olaf, Roy, Anindita, Roberts, Irene, Konopleva, Marina, Klose, Robert J., Geng, Huimin, Milne, Thomas A.
Publicado 2017

DOT1L inhibition reveals a distinct subset of enhancers dependent on H3K79 methylation

por Godfrey, Laura, Crump, Nicholas T., Thorne, Ross, Lau, I-Jun, Repapi, Emmanouela, Dimou, Dimitra, Smith, Alastair L., Harman, Joe R., Telenius, Jelena M., Oudelaar, A. Marieke, Downes, Damien J., Vyas, Paresh, Hughes, Jim R., Milne, Thomas A.
Publicado 2019

Molecular heterogeneity and commonalities in pancreatic cancer precursors with gastric and intestinal phenotype

por Liffers, Sven-Thorsten, Godfrey, Laura, Frohn, Lisa, Haeberle, Lena, Yavas, Aslihan, Vesce, Rita, Goering, Wolfgang, Opitz, Friederike V, Stoecklein, Nickolas, Knoefel, Wolfram Trudo, Schlitter, Anna Melissa, Klöppel, Guenter, Espinet, Elisa, Trumpp, Andreas, Siveke, Jens T, Esposito, Irene
Publicado 2023

H3K79me2/3 controls enhancer–promoter interactions and activation of the pan-cancer stem cell marker PROM1/CD133 in MLL-AF4 leukemia cells

por Godfrey, Laura, Crump, Nicholas T., O’Byrne, Sorcha, Lau, I-Jun, Rice, Siobhan, Harman, Joe R., Jackson, Thomas, Elliott, Natalina, Buck, Gemma, Connor, Christopher, Thorne, Ross, Knapp, David J. H. F., Heidenreich, Olaf, Vyas, Paresh, Menendez, Pablo, Inglott, Sarah, Ancliff, Philip, Geng, Huimin, Roberts, Irene, Roy, Anindita, Milne, Thomas A.
Publicado 2020

MLL-AF4 cooperates with PAF1 and FACT to drive high-density enhancer interactions in leukemia

por Crump, Nicholas T., Smith, Alastair L., Godfrey, Laura, Dopico-Fernandez, Ana M., Denny, Nicholas, Harman, Joe R., Hamley, Joseph C., Jackson, Nicole E., Chahrour, Catherine, Riva, Simone, Rice, Siobhan, Kim, Jaehoon, Basrur, Venkatesha, Fermin, Damian, Elenitoba-Johnson, Kojo, Roeder, Robert G., Allis, C. David, Roberts, Irene, Roy, Anindita, Geng, Huimin, Davies, James O. J., Milne, Thomas A.
Publicado 2023

Chromatin accessibility governs the differential response of cancer and T cells to arginine starvation

por Crump, Nicholas T., Hadjinicolaou, Andreas V., Xia, Meng, Walsby-Tickle, John, Gileadi, Uzi, Chen, Ji-Li, Setshedi, Mashiko, Olsen, Lars R., Lau, I-Jun, Godfrey, Laura, Quek, Lynn, Yu, Zhanru, Ballabio, Erica, Barnkob, Mike B., Napolitani, Giorgio, Salio, Mariolina, Koohy, Hashem, Kessler, Benedikt M., Taylor, Stephen, Vyas, Paresh, McCullagh, James S.O., Milne, Thomas A., Cerundolo, Vincenzo
Publicado 2021

Functional noninvasive detection of glycolytic pancreatic ductal adenocarcinoma

por Heid, Irina, Münch, Corinna, Karakaya, Sinan, Lueong, Smiths S., Winkelkotte, Alina M., Liffers, Sven T., Godfrey, Laura, Cheung, Phyllis F. Y., Savvatakis, Konstantinos, Topping, Geoffrey J., Englert, Florian, Kritzner, Lukas, Grashei, Martin, Tannapfel, Andrea, Viebahn, Richard, Wolters, Heiner, Uhl, Waldemar, Vangala, Deepak, Smeets, Esther M. M., Aarntzen, Erik H. J. G., Rauh, Daniel, Weichert, Wilko, Hoheisel, Jörg D., Hahn, Stephan A., Schilling, Franz, Braren, Rickmer, Trajkovic-Arsic, Marija, Siveke, Jens T.
Publicado 2022

Secondary resistance to anti-EGFR therapy by transcriptional reprogramming in patient-derived colorectal cancer models

por Vangala, Deepak, Ladigan, Swetlana, Liffers, Sven T., Noseir, Soha, Maghnouj, Abdelouahid, Götze, Tina-Maria, Verdoodt, Berlinda, Klein-Scory, Susanne, Godfrey, Laura, Zowada, Martina K., Huerta, Mario, Edelstein, Daniel L., de Villarreal, Jaime Martinez, Marqués, Miriam, Kumbrink, Jörg, Jung, Andreas, Schiergens, Tobias, Werner, Jens, Heinemann, Volker, Stintzing, Sebastian, Lindoerfer, Doris, Mansmann, Ulrich, Pohl, Michael, Teschendorf, Christian, Bernhardt, Christiane, Wolters, Heiner, Stern, Josef, Usta, Selami, Viebahn, Richard, Admard, Jacob, Casadei, Nicolas, Fröhling, Stefan, Ball, Claudia R., Siveke, Jens T., Glimm, Hanno, Tannapfel, Andrea, Schmiegel, Wolff, Hahn, Stephan A.
Publicado 2021

MAPK-pathway inhibition mediates inflammatory reprogramming and sensitizes tumors to targeted activation of innate immunity sensor RIG-I

por Brägelmann, Johannes, Lorenz, Carina, Borchmann, Sven, Nishii, Kazuya, Wegner, Julia, Meder, Lydia, Ostendorp, Jenny, Ast, David F., Heimsoeth, Alena, Nakasuka, Takamasa, Hirabae, Atsuko, Okawa, Sachi, Dammert, Marcel A., Plenker, Dennis, Klein, Sebastian, Lohneis, Philipp, Gu, Jianing, Godfrey, Laura K., Forster, Jan, Trajkovic-Arsic, Marija, Zillinger, Thomas, Haarmann, Mareike, Quaas, Alexander, Lennartz, Stefanie, Schmiel, Marcel, D’Rozario, Joshua, Thomas, Emily S., Li, Henry, Schmitt, Clemens A., George, Julie, Thomas, Roman K., von Karstedt, Silvia, Hartmann, Gunther, Büttner, Reinhard, Ullrich, Roland T., Siveke, Jens T., Ohashi, Kadoaki, Schlee, Martin, Sos, Martin L.
Publicado 2021

MLL-Rearranged Acute Lymphoblastic Leukemias Activate BCL-2 through H3K79 Methylation and Are Sensitive to the BCL-2-Specific Antagonist ABT-199

por Benito, Juliana M., Godfrey, Laura, Kojima, Kensuke, Hogdal, Leah, Wunderlich, Mark, Geng, Huimin, Marzo, Isabel, Harutyunyan, Karine G., Golfman, Leonard, North, Phillip, Kerry, Jon, Ballabio, Erica, Chonghaile, Triona Ní, Gonzalo, Oscar, Qiu, Yihua, Jeremias, Irmela, Debose, LaKiesha, O’Brien, Eric, Ma, Helen, Zhou, Ping, Jacamo, Rodrigo, Park, Eugene, Coombes, Kevin R., Zhang, Nianxiang, Thomas, Deborah A., O’Brien, Susan, Kantarjian, Hagop M., Leverson, Joel D., Kornblau, Steven M., Andreeff, Michael, Müschen, Markus, Zweidler-McKay, Patrick A., Mulloy, James C., Letai, Anthony, Milne, Thomas A., Konopleva, Marina
Publicado 2015