Cancer vaccines: shared tumor antigens return to the spotlight

por Li, Lijin, Goedegebuure, S. Peter, Gillanders, William
Publicado 2020

Single-cell transcriptomics reveals long noncoding RNAs associated with tumor biology and the microenvironment in pancreatic cancer

por Dang, Ha X, Saha, Debanjan, Jayasinghe, Reyka, Zhao, Sidi, Coonrod, Emily, Mudd, Jacqueline, Goedegebuure, S Peter, Fields, Ryan, Ding, Li, Maher, Christopher A
Publicado 2023

Engineering a Novel Modular Adenoviral mRNA Delivery Platform Based on Tag/Catcher Bioconjugation

por Geng, Kexin, Rice-Boucher, Paul J., Kashentseva, Elena A., Dmitriev, Igor P., Lu, Zhi Hong, Goedegebuure, S. Peter, Gillanders, William E., Curiel, David T.
Publicado 2023

The Targeted SMAC Mimetic SW IV-134 is a strong enhancer of standard chemotherapy in pancreatic cancer

por Hashim, Yassar M., Vangveravong, Suwanna, Sankpal, Narendra V., Binder, Pratibha S., Liu, Jingxia, Goedegebuure, S. Peter, Mach, Robert H., Spitzer, Dirk, Hawkins, William G.
Publicado 2017

Membrane-proximal TRAIL species are incapable of inducing short circuit apoptosis signaling: Implications for drug development and basic cytokine biology

por Tatzel, Katharina, Kuroki, Lindsay, Dmitriev, Igor, Kashentseva, Elena, Curiel, David T., Goedegebuure, S. Peter, Powell, Matthew A., Mutch, David G., Hawkins, William G., Spitzer, Dirk
Publicado 2016

Erratum: Membrane-proximal TRAIL species are incapable of inducing short circuit apoptosis signaling: Implications for drug development and basic cytokine biology

por Tatzel, Katharina, Kuroki, Lindsay, Dmitriev, Igor, Kashentseva, Elena, Curiel, David T., Goedegebuure, S. Peter, Powell, Matthew A., Mutch, David G., Hawkins, William G., Spitzer, Dirk
Publicado 2016

Defining a murine ovarian cancer model for the evaluation of conditionally-replicative adenovirus (CRAd) virotherapy agents

por González-Pastor, Rebeca, Ashshi, Ahmad Mohammad, El-Shemi, Adel Galal, Dmitriev, Igor P., Kashentseva, Elena A., Lu, Zhi Hong, Goedegebuure, S. Peter, Podhajcer, Osvaldo L., Curiel, David T.
Publicado 2019

Combination TIGIT/PD-1 blockade enhances the efficacy of neoantigen vaccines in a model of pancreatic cancer

por Peng, Hui, Li, Lijin, Zuo, Chong, Chen, Michael Y., Zhang, Xiuli, Myers, Nancy B., Hogg, Graham D., DeNardo, David G., Goedegebuure, S. Peter, Hawkins, William G., Gillanders, William E.
Publicado 2022

Tumor-induced STAT3 activation in monocytic myeloid-derived suppressor cells enhances stemness and mesenchymal properties in human pancreatic cancer

por Panni, Roheena Z., Sanford, Dominic E., Belt, Brian A., Mitchem, Jonathan B., Worley, Lori A., Goetz, Brian D., Mukherjee, Pinku, Wang-Gillam, Andrea, Link, Daniel C., DeNardo, David G., Goedegebuure, S. Peter, Linehan, David C.
Publicado 2014

Development of an adenovirus vector vaccine platform for targeting dendritic cells

por Sharma, Piyush K, Dmitriev, Igor P, Kashentseva, Elena A, Raes, Geert, Li, Lijin, Kim, Samuel W, Lu, Zhi-Hong, Arbeit, Jeffrey M, Fleming, Timothy P, Kaliberov, Sergey A, Goedegebuure, S Peter, Curiel, David T, Gillanders, William E
Publicado 2017

In Silico Epitope Prediction Analyses Highlight the Potential for Distracting Antigen Immunodominance with Allogeneic Cancer Vaccines

por James, C. Alston, Ronning, Peter, Cullinan, Darren, Cotto, Kelsy C., Barnell, Erica K., Campbell, Katie M., Skidmore, Zachary L., Sanford, Dominic E., Goedegebuure, S. Peter, Gillanders, William E., Griffith, Obi L., Hawkins, William G., Griffith, Malachi
Publicado 2021

Precision delivery of RAS-inhibiting siRNA to KRAS driven cancer via peptide-based nanoparticles

por Strand, Matthew S., Krasnick, Bradley A., Pan, Hua, Zhang, Xiuli, Bi, Ye, Brooks, Candace, Wetzel, Christopher, Sankpal, Narendra, Fleming, Timothy, Goedegebuure, S. Peter, DeNardo, David G., Gillanders, William E., Hawkins, William G., Wickline, Samuel A., Fields, Ryan C.
Publicado 2019

Neoadjuvant FOLFIRINOX Therapy Is Associated with Increased Effector T Cells and Reduced Suppressor Cells in Patients with Pancreatic Cancer

por Peng, Hui, James, C. Alston, Cullinan, Darren R., Hogg, Graham D., Mudd, Jacqueline L., Zuo, Chong, Takchi, Rony, Caldwell, Katharine E., Liu, Jingxia, DeNardo, David G., Fields, Ryan C., Gillanders, William E., Goedegebuure, S. Peter, Hawkins, William G.
Publicado 2021

Conjugation to the sigma-2 ligand SV119 overcomes uptake blockade and converts dm-Erastin into a potent pancreatic cancer therapeutic

por Ohman, Kerri A., Hashim, Yassar M., Vangveravong, Suwanna, Nywening, Timothy M., Cullinan, Darren R., Goedegebuure, S. Peter, Liu, Jingxia, Van Tine, Brian A., Tiriac, Herve, Tuveson, David A., DeNardo, David G., Spitzer, Dirk, Mach, Robert H., Hawkins, William G.
Publicado 2016

Proteins in Tumor-Derived Plasma Extracellular Vesicles Indicate Tumor Origin

por Barlin, Meltem, Erdmann-Gilmore, Petra, Mudd, Jacqueline L., Zhang, Qiang, Seymour, Robert W., Guo, Zhanfang, Miessner, Julia R., Goedegebuure, S. Peter, Bi, Ye, Osorio, Omar A., Alexander-Brett, Jennifer, Li, Shunqiang, Ma, Cynthia X., Fields, Ryan C., Townsend, R. Reid, Held, Jason M.
Publicado 2022

Induction of cancer neoantigens facilitates development of clinically relevant models for the study of pancreatic cancer immunobiology

por Panni, Usman Y., Chen, Michael Y., Zhang, Felicia, Cullinan, Darren R., Li, Lijin, James, C. Alston, Zhang, Xiuli, Rogers, S., Alarcon, A., Baer, John M., Zhang, Daoxiang, Gao, Feng, Miller, Christopher A., Gong, Qingqing, Lim, Kian-Huat, DeNardo, David G., Goedegebuure, S. Peter, Gillanders, William E., Hawkins, William G.
Publicado 2023

Optimized polyepitope neoantigen DNA vaccines elicit neoantigen-specific immune responses in preclinical models and in clinical translation

por Li, Lijin, Zhang, Xiuli, Wang, Xiaoli, Kim, Samuel W., Herndon, John M., Becker-Hapak, Michelle K., Carreno, Beatriz M., Myers, Nancy B., Sturmoski, Mark A., McLellan, Michael D., Miller, Christopher A., Johanns, Tanner M., Tan, Benjamin R., Dunn, Gavin P., Fleming, Timothy P., Hansen, Ted H., Goedegebuure, S. Peter, Gillanders, William E.
Publicado 2021

Long non-coding RNA RAMS11 promotes metastatic colorectal cancer progression

por Silva-Fisher, Jessica M., Dang, Ha X., White, Nicole M., Strand, Matthew S., Krasnick, Bradley A., Rozycki, Emily B., Jeffers, Gejae G. L., Grossman, Julie G., Highkin, Maureen K., Tang, Cynthia, Cabanski, Christopher R., Eteleeb, Abdallah, Mudd, Jacqueline, Goedegebuure, S. Peter, Luo, Jingqin, Mardis, Elaine R., Wilson, Richard K., Ley, Timothy J., Lockhart, Albert C., Fields, Ryan C., Maher, Christopher A.
Publicado 2020

The clonal evolution of metastatic colorectal cancer

por Dang, Ha X., Krasnick, Bradley A., White, Brian S., Grossman, Julie G., Strand, Matthew S., Zhang, Jin, Cabanski, Christopher R., Miller, Christopher A., Fulton, Robert S., Goedegebuure, S. Peter, Fronick, Catrina C., Griffith, Malachi, Larson, David E., Goetz, Brian D., Walker, Jason R., Hawkins, William G., Strasberg, Steven M., Linehan, David C., Lim, Kian H., Lockhart, A. Craig, Mardis, Elaine R., Wilson, Richard K., Ley, Timothy J., Maher, Christopher A., Fields, Ryan C.
Publicado 2020

Autologous humanized PDX modeling for immuno-oncology recapitulates features of the human tumor microenvironment

por Chiorazzi, Michael, Martinek, Jan, Krasnick, Bradley, Zheng, Yunjiang, Robbins, Keenan J, Qu, Rihao, Kaufmann, Gabriel, Skidmore, Zachary, Juric, Melani, Henze, Laura A, Brösecke, Frederic, Adonyi, Adam, Zhao, Jun, Shan, Liang, Sefik, Esen, Mudd, Jacqueline, Bi, Ye, Goedegebuure, S Peter, Griffith, Malachi, Griffith, Obi, Oyedeji, Abimbola, Fertuzinhos, Sofia, Garcia-Milian, Rolando, Boffa, Daniel, Detterbeck, Frank, Dhanasopon, Andrew, Blasberg, Justin, Judson, Benjamin, Gettinger, Scott, Politi, Katerina, Kluger, Yuval, Palucka, Karolina, Fields, Ryan C, Flavell, Richard A
Publicado 2023