The mouse metallomic landscape of aging and metabolism

por Morel, Jean-David, Sauzéat, Lucie, Goeminne, Ludger J. E., Jha, Pooja, Williams, Evan, Houtkooper, Riekelt H., Aebersold, Ruedi, Auwerx, Johan, Balter, Vincent
Publicado 2022

Multi-omics characterization of partial chemical reprogramming reveals evidence of cell rejuvenation

por Mitchell, Wayne, Goeminne, Ludger J.E., Tyshkovskiy, Alexander, Zhang, Sirui, Paulo, Joao A., Pierce, Kerry A., Choy, Angelina H., Clish, Clary B., Gygi, Steven P., Gladyshev, Vadim N.
Publicado 2023

The transcriptional coactivator CBP/p300 is an evolutionarily conserved node that promotes longevity in response to mitochondrial stress

por Li, Terytty Yang, Sleiman, Maroun Bou, Li, Hao, Gao, Arwen W., Mottis, Adrienne, Bachmann, Alexis Maximilien, El Alam, Gaby, Li, Xiaoxu, Goeminne, Ludger J. E., Schoonjans, Kristina, Auwerx, Johan
Publicado 2021

Inhibition of sphingolipid de novo synthesis counteracts muscular dystrophy

por Laurila, Pirkka-Pekka, Luan, Peiling, Wohlwend, Martin, Zanou, Nadège, Crisol, Barbara, Imamura de Lima, Tanes, Goeminne, Ludger J. E., Gallart-Ayala, Hector, Shong, Minho, Ivanisevic, Julijana, Place, Nicolas, Auwerx, Johan
Publicado 2022

Genetic background and sex control the outcome of high-fat diet feeding in mice

por Bachmann, Alexis Maximilien, Morel, Jean-David, El Alam, Gaby, Rodríguez-López, Sandra, Imamura de lima, Tanes, Goeminne, Ludger J.E., Benegiamo, Giorgia, Loric, Sylvain, Conti, Marc, Sleiman, Maroun Bou, Auwerx, Johan
Publicado 2022

COX7A2L genetic variants determine cardiorespiratory fitness in mice and human

por Benegiamo, Giorgia, Bou Sleiman, Maroun, Wohlwend, Martin, Rodríguez-López, Sandra, Goeminne, Ludger J. E., Laurila, Pirkka-Pekka, Klevjer, Marie, Salonen, Minna K., Lahti, Jari, Jha, Pooja, Cogliati, Sara, Enriquez, José Antonio, Brumpton, Ben M., Bye, Anja, Eriksson, Johan G., Auwerx, Johan
Publicado 2022

Growth differentiation factor 15 protects against the aging‐mediated systemic inflammatory response in humans and mice

por Moon, Ji Sun, Goeminne, Ludger J. E., Kim, Jung Tae, Tian, Jing Wen, Kim, Seok‐Hwan, Nga, Ha Thi, Kang, Seul Gi, Kang, Baeki E., Byun, Jin‐Seok, Lee, Young‐Sun, Jeon, Jae‐Han, Shong, Minho, Auwerx, Johan, Ryu, Dongryeol, Yi, Hyon‐Seung
Publicado 2020

The genetic background shapes the susceptibility to mitochondrial dysfunction and NASH progression

por Benegiamo, Giorgia, von Alvensleben, Giacomo V.G., Rodríguez-López, Sandra, Goeminne, Ludger J.E., Bachmann, Alexis M., Morel, Jean-David, Broeckx, Ellen, Ma, Jing Ying, Carreira, Vinicius, Youssef, Sameh A., Azhar, Nabil, Reilly, Dermot F., D’Aquino, Katharine, Mullican, Shannon, Bou-Sleiman, Maroun, Auwerx, Johan
Publicado 2023

Integrative systems analysis identifies genetic and dietary modulators of bile acid homeostasis

por Li, Hao, Perino, Alessia, Huang, Qingyao, Von Alvensleben, Giacomo V.G., Banaei-Esfahani, Amir, Velazquez-Villegas, Laura A., Gariani, Karim, Korbelius, Melanie, Bou Sleiman, Maroun, Imbach, Jéromine, Sun, Yu, Li, Xiaoxu, Bachmann, Alexis, Goeminne, Ludger J.E., Gallart-Ayala, Hector, Williams, Evan G., Ivanisevic, Julijana, Auwerx, Johan, Schoonjans, Kristina
Publicado 2022

Evidence for a neuromuscular circuit involving hypothalamic interleukin-6 in the control of skeletal muscle metabolism

por Katashima, Carlos Kiyoshi, de Oliveira Micheletti, Thayana, Braga, Renata Rosseto, Gaspar, Rodrigo Stellzer, Goeminne, Ludger J. E., Moura-Assis, Alexandre, Crisol, Barbara Moreira, Brícola, Rafael S., Silva, Vagner Ramon R., de Oliveira Ramos, Camila, da Rocha, Alisson L., Tavares, Mariana Rosolen, Simabuco, Fernando Moreira, Matheus, Valquiria Aparecida, Buscaratti, Lucas, Marques-Souza, Henrique, Pazos, Patricia, Gonzalez-Touceda, David, Tovar, Sulay, del Carmen García, María, Neto, Jose Cesar Rosa, Curi, Rui, Hirabara, Sandro Massao, Brum, Patrícia Chakur, Prada, Patrícia Oliveira, de Moura, Leandro P., Pauli, José Rodrigo, da Silva, Adelino S. R., Cintra, Dennys Esper, Velloso, Licio A., Ropelle, Eduardo Rochete
Publicado 2022