Nanobody Based Dual Specific CARs

por De Munter, Stijn, Ingels, Joline, Goetgeluk, Glenn, Bonte, Sarah, Pille, Melissa, Weening, Karin, Kerre, Tessa, Abken, Hinrich, Vandekerckhove, Bart
Publicado 2018

T-cells with a single tumor antigen-specific T-cell receptor can be generated in vitro from clinically relevant stem cell sources

por Bonte, Sarah, De Munter, Stijn, Goetgeluk, Glenn, Ingels, Joline, Pille, Melissa, Billiet, Lore, Taghon, Tom, Leclercq, Georges, Vandekerckhove, Bart, Kerre, Tessa
Publicado 2020

In vitro OP9-DL1 co-culture and subsequent maturation in the presence of IL-21 generates tumor antigen-specific T cells with a favorable less-differentiated phenotype and enhanced...

por Bonte, Sarah, de Munter, Stijn, Billiet, Lore, Goetgeluk, Glenn, Ingels, Joline, Jansen, Hanne, Pille, Melissa, de Cock, Laurenz, Weening, Karin, Taghon, Tom, Leclercq, Georges, Vandekerckhove, Bart, Kerre, Tessa
Publicado 2021

Antigen receptor-redirected T cells derived from hematopoietic precursor cells lack expression of the endogenous TCR/CD3 receptor and exhibit specific antitumor capacities

por Van Caeneghem, Yasmine, De Munter, Stijn, Tieppo, Paola, Goetgeluk, Glenn, Weening, Karin, Verstichel, Greet, Bonte, Sarah, Taghon, Tom, Leclercq, Georges, Kerre, Tessa, Debets, Reno, Vermijlen, David, Abken, Hinrich, Vandekerckhove, Bart
Publicado 2017

Human Thymic CD10(+) PD-1(+) Intraepithelial Lymphocyte Precursors Acquire Interleukin-15 Responsiveness at the CD1a(–) CD95(+) CD28(–) CCR7(–) Developmental Stage

por Billiet, Lore, Goetgeluk, Glenn, Bonte, Sarah, De Munter, Stijn, De Cock, Laurenz, Pille, Melissa, Ingels, Joline, Jansen, Hanne, Weening, Karin, Van Nieuwerburgh, Filip, Kerre, Tessa, Taghon, Tom, Leclercq, Georges, Vandekerckhove, Bart
Publicado 2020

The human fetal thymus generates invariant effector γδ T cells

por Tieppo, Paola, Papadopoulou, Maria, Gatti, Deborah, McGovern, Naomi, Chan, Jerry K.Y., Gosselin, Françoise, Goetgeluk, Glenn, Weening, Karin, Ma, Ling, Dauby, Nicolas, Cogan, Alexandra, Donner, Catherine, Ginhoux, Florent, Vandekerckhove, Bart, Vermijlen, David
Publicado 2019

Intracellular Delivery of mRNA in Adherent and Suspension Cells by Vapor Nanobubble Photoporation

por Raes, Laurens, Stremersch, Stephan, Fraire, Juan C., Brans, Toon, Goetgeluk, Glenn, De Munter, Stijn, Van Hoecke, Lien, Verbeke, Rein, Van Hoeck, Jelter, Xiong, Ranhua, Saelens, Xavier, Vandekerckhove, Bart, De Smedt, Stefaan, Raemdonck, Koen, Braeckmans, Kevin
Publicado 2020

Rapid and Effective Generation of Nanobody Based CARs using PCR and Gibson Assembly

por De Munter, Stijn, Van Parys, Alexander, Bral, Layla, Ingels, Joline, Goetgeluk, Glenn, Bonte, Sarah, Pille, Melissa, Billiet, Lore, Weening, Karin, Verhee, Annick, Van der Heyden, Jose, Taghon, Tom, Leclercq, Georges, Kerre, Tessa, Tavernier, Jan, Vandekerckhove, Bart
Publicado 2020

Cas9 RNP transfection by vapor nanobubble photoporation for ex vivo cell engineering

por Raes, Laurens, Pille, Melissa, Harizaj, Aranit, Goetgeluk, Glenn, Van Hoeck, Jelter, Stremersch, Stephan, Fraire, Juan C., Brans, Toon, de Jong, Olivier Gerrit, Maas-Bakker, Roel, Mastrobattista, Enrico, Vader, Pieter, De Smedt, Stefaan C., Vandekerckhove, Bart, Raemdonck, Koen, Braeckmans, Kevin
Publicado 2021

The Wiskott–Aldrich syndrome protein is required for positive selection during T-cell lineage differentiation

por Pille, Melissa, Avila, John, Sanchez, Guillem Sanchez, Goetgeluk, Glenn, De Munter, Stijn, Jansen, Hanne, Billiet, Lore, Weening, Karin, Xue, Haipeng, Bonte, Sarah, Ingels, Joline, De Cock, Laurenz, Pascal, Eva, Deseins, Lucas, Kerre, Tessa, Taghon, Tom, Leclercq, Georges, Vermijlen, David, Davis, Brian, Vandekerckhove, Bart
Publicado 2023

TARP is an immunotherapeutic target in acute myeloid leukemia expressed in the leukemic stem cell compartment

por Depreter, Barbara, Weening, Karin E., Vandepoele, Karl, Essand, Magnus, De Moerloose, Barbara, Themeli, Maria, Cloos, Jacqueline, Hanekamp, Diana, Moors, Ine, D’hont, Inge, Denys, Barbara, Uyttebroeck, Anne, Van Damme, An, Dedeken, Laurence, Snauwaert, Sylvia, Goetgeluk, Glenn, De Munter, Stijn, Kerre, Tessa, Vandekerckhove, Bart, Lammens, Tim, Philippé, Jan
Publicado 2020

Single-cell profiling identifies a novel human polyclonal unconventional T cell lineage

por Billiet, Lore, De Cock, Laurenz, Sanchez Sanchez, Guillem, Mayer, Rupert L., Goetgeluk, Glenn, De Munter, Stijn, Pille, Melissa, Ingels, Joline, Jansen, Hanne, Weening, Karin, Pascal, Eva, Raes, Killian, Bonte, Sarah, Kerre, Tessa, Vandamme, Niels, Seurinck, Ruth, Roels, Jana, Lavaert, Marieke, Van Nieuwerburgh, Filip, Leclercq, Georges, Taghon, Tom, Impens, Francis, Menten, Björn, Vermijlen, David, Vandekerckhove, Bart
Publicado 2023

Photothermal nanofibers enable safe engineering of therapeutic cells

por Xiong, Ranhua, Hua, Dawei, Hoeck, Jelter Van, Berdecka, Dominika, Léger, Laurens, De Munter, Stijn, Fraire, Juan C., Raes, Laurens, Harizaj, Aranit, Sauvage, Félix, Goetgeluk, Glenn, Pille, Melissa, Aalders, Jeffrey, Belza, Joke, Van Acker, Thibaut, Bolea-Fernandez, Eduardo, Si, Ting, Vanhaecke, Frank, De Vos, Winnok H., Vandekerckhove, Bart, van Hengel, Jolanda, Raemdonck, Koen, Huang, Chaobo, De Smedt, Stefaan C., Braeckmans, Kevin
Publicado 2021