Herpes Simplex Virus Vectors for Gene Transfer to the Central Nervous System

por Artusi, Sara, Miyagawa, Yoshitaka, Goins, William F., Cohen, Justus B., Glorioso, Joseph C.
Publicado 2018

Novel mutations in U(L)24 and gH rescue efficient infection of an HSV vector retargeted to TrkA

por Marzulli, Marco, Hall, Bonnie L., Zhang, Mingdi, Goins, William F., Cohen, Justus B., Glorioso, Joseph C.
Publicado 2023

Generation of an Oncolytic Herpes Simplex Viral Vector Completely Retargeted to the GDNF Receptor GFRα1 for Specific Infection of Breast Cancer Cells

por Hall, Bonnie L., Leronni, Daniela, Miyagawa, Yoshitaka, Goins, William F., Glorioso, Joseph C., Cohen, Justus B.
Publicado 2020

Effects of Herpes Simplex Virus Vectors Encoding Poreless TRPV1 or Protein Phosphatase 1α in a Rat Cystitis Model induced by Hydrogen Peroxide

por Takai, Shun, Majima, Tsuyoshi, Reinhart, Bonne, Goins, William F., Funahashi, Yasuhito, Gotoh, Momokazu, Tyagi, Pradeep, Glorioso, Joseph C., Yoshimura, Naoki
Publicado 2017

Deletion of the Virion Host Shut-off Gene Enhances Neuronal-Selective Transgene Expression from an HSV Vector Lacking Functional IE Genes

por Miyagawa, Yoshitaka, Verlengia, Gianluca, Reinhart, Bonnie, Han, Fang, Uchida, Hiroaki, Zucchini, Silvia, Goins, William F., Simonato, Michele, Cohen, Justus B., Glorioso, Joseph C.
Publicado 2017

An HSV-based library screen identifies PP1α as a negative TRPV1 regulator with analgesic activity in models of pain

por Reinhart, Bonnie, Goins, William F, Harel, Asaff, Chaudhry, Suchita, Goss, James R, Yoshimura, Naoki, de Groat, William C, Cohen, Justus B, Glorioso, Joseph C
Publicado 2016

MnSOD mediated by HSV vectors in the periaqueductal gray suppresses morphine withdrawal in rats

por Iida, Takafumi, Yi, Hyun, Liu, Shue, Ikegami, Daigo, Zheng, Wenwen, Liu, Qiaofeng, Takahashi, Keiya, Kashiwagi, Yuta, Goins, William F., Glorioso, Joseph C., Hao, Shuanglin
Publicado 2017

Varicella-zoster virus early infection but not complete replication is required for the induction of chronic hypersensitivity in rat models of postherpetic neuralgia

por Warner, Benjamin E., Yee, Michael B., Zhang, Mingdi, Hornung, Rebecca S., Kaufer, Benedikt B., Visalli, Robert J., Kramer, Phillip R., Goins, William F., Kinchington, Paul R.
Publicado 2021

Evaluation of parameters for efficient purification and long-term storage of herpes simplex virus-based vectors

por Kuroda, Seiji, Miyagawa, Yoshitaka, Sukegawa, Makoto, Tomono, Taro, Yamamoto, Motoko, Adachi, Kumi, Verlengia, Gianluca, Goins, William F., Cohen, Justus B., Glorioso, Joseph C., Okada, Takashi
Publicado 2022

Agent-based computational modeling of glioblastoma predicts that stromal density is central to oncolytic virus efficacy

por Jenner, Adrianne L., Smalley, Munisha, Goldman, David, Goins, William F., Cobbs, Charles S., Puchalski, Ralph B., Chiocca, E. Antonio, Lawler, Sean, Macklin, Paul, Goldman, Aaron, Craig, Morgan
Publicado 2022

Protocol Optimization for the Production of the Non-Cytotoxic JΔNI5 HSV Vector Deficient in Expression of Immediately Early Genes

por Kuroda, Seiji, Miyagawa, Yoshitaka, Sato, Yuriko, Yamamoto, Motoko, Adachi, Kumi, Kinoh, Hiromi, Goins, William F., Cohen, Justus B., Glorioso, Joseph C., Taniai, Nobuhiko, Yoshida, Hiroshi, Okada, Takashi
Publicado 2020

Treatment of glioblastoma with current oHSV variants reveals differences in efficacy and immune cell recruitment

por Jackson, Joseph W., Hall, Bonnie L., Marzulli, Marco, Shah, Vrusha K., Bailey, Lisa, Chiocca, E. Antonio, Goins, William F., Kohanbash, Gary, Cohen, Justus B., Glorioso, Joseph C.
Publicado 2021

Myelolytic Treatments Enhance Oncolytic Herpes Virotherapy in Models of Ewing Sarcoma by Modulating the Immune Microenvironment

por Denton, Nicholas L., Chen, Chun-Yu, Hutzen, Brian, Currier, Mark A., Scott, Thomas, Nartker, Brooke, Leddon, Jennifer L., Wang, Pin-Yi, Srinivas, Rachelle, Cassady, Kevin A., Goins, William F., Cripe, Timothy P.
Publicado 2018

GBM-Targeted oHSV Armed with Matrix Metalloproteinase 9 Enhances Anti-tumor Activity and Animal Survival

por Sette, Paola, Amankulor, Nduka, Li, Aofei, Marzulli, Marco, Leronni, Daniela, Zhang, Mingdi, Goins, William F., Kaur, Balveen, Bolyard, Chelsea, Cripe, Timothy P., Yu, Jianhua, Chiocca, E. Antonio, Glorioso, Joseph C., Grandi, Paola
Publicado 2019

Glioblastoma infiltration of both tumor- and virus-antigen specific cytotoxic T cells correlates with experimental virotherapy responses

por Alayo, Quazim A., Ito, Hirotaka, Passaro, Carmela, Zdioruk, Mykola, Mahmoud, Ahmad Bakur, Grauwet, Korneel, Zhang, Xiaoli, Lawler, Sean E., Reardon, David A., Goins, William F., Fernandez, Soledad, Chiocca, E. Antonio, Nakashima, Hiroshi
Publicado 2020

Expression of HSV-1 Receptors in EBV-Associated Lymphoproliferative Disease Determines Susceptibility to Oncolytic HSV

por Wang, Pin-Yi, Currier, Mark A, Hansford, Loen, Kaplan, David, Chiocca, E. Antonio, Uchida, Hiroaki, Goins, William F., Cohen, Justus B., Glorioso, Joseph C., van Kuppevelt, Toin H., Mo, Xiaokui, Cripe, Timothy P
Publicado 2012

THER-02. Pediatric brain tumor cultures reveal differential susceptibility to four oncolytic viruses

por Vazaios, Konstantinos, Stavrakaki, Eftychia, Vogelezang, Lisette, van den Hoogen, Bernadette, Hoeben, Rob C, Chiocca, Antonio E, Goins, William F, Hulleman, Esther, Straetemans, Trudy, Calkoen, Friso G J, van der Lugt, Jasper, Lamfers, Martine L M
Publicado 2022

Current gene therapy using viral vectors for chronic pain

por Guedon, Jean-Marc G, Wu, Shaogen, Zheng, Xuexing, Churchill, Caroline C, Glorioso, Joseph C, Liu, Ching-Hang, Liu, Shue, Vulchanova, Lucy, Bekker, Alex, Tao, Yuan-Xiang, Kinchington, Paul R, Goins, William F, Fairbanks, Carolyn A, Hao, Shuanglin
Publicado 2015

Oncolytic HSV virotherapy in murine sarcomas differentially triggers an antitumor T-cell response in the absence of virus permissivity

por Leddon, Jennifer L, Chen, Chun-Yu, Currier, Mark A, Wang, Pin-Yi, Jung, Francesca A, Denton, Nicholas L, Cripe, Kevin M, Haworth, Kellie B, Arnold, Michael A, Gross, Amy C, Eubank, Timothy D, Goins, William F, Glorioso, Joseph C, Cohen, Justus B, Grandi, Paola, Hildeman, David A, Cripe, Timothy P
Publicado 2015