PROTEIN SYNTHESIS DURING WORK-INDUCED GROWTH OF SKELETAL MUSCLE

por Goldberg, Alfred L.
Publicado 1968

Development of proteasome inhibitors as research tools and cancer drugs

por Goldberg, Alfred L.
Publicado 2012

Heat shock and oxygen radicals stimulate ubiquitin-dependent degradation mainly of newly synthesized proteins

por Medicherla, Balasubrahmanyam, Goldberg, Alfred L.
Publicado 2008

26S proteasomes become stably activated upon heat shock when ubiquitination and protein degradation increase

por Lee, Donghoon, Goldberg, Alfred L.
Publicado 2022

NONUNIFORM RATES OF TURNOVER OF MYOFIBRILLAR PROTEINS IN RAT DIAPHRAGM

por Low, Robert B., Goldberg, Alfred L.
Publicado 1973

Mechanisms of skeletal muscle aging: insights from Drosophila and mammalian models

por Demontis, Fabio, Piccirillo, Rosanna, Goldberg, Alfred L., Perrimon, Norbert
Publicado 2013

Ubiquitylation by Trim32 causes coupled loss of desmin, Z-bands, and thin filaments in muscle atrophy

por Cohen, Shenhav, Zhai, Bo, Gygi, Steven P., Goldberg, Alfred L.
Publicado 2012

Characterization of the Brain 26S Proteasome and its Interacting Proteins

por Tai, Hwan-Ching, Besche, Henrike, Goldberg, Alfred L., Schuman, Erin M.
Publicado 2010

Mechanisms That Activate 26S Proteasomes and Enhance Protein Degradation

por Goldberg, Alfred L., Kim, Hyoung Tae, Lee, Donghoon, Collins, Galen Andrew
Publicado 2021

Trim32 reduces PI3K–Akt–FoxO signaling in muscle atrophy by promoting plakoglobin–PI3K dissociation

por Cohen, Shenhav, Lee, Donghoon, Zhai, Bo, Gygi, Steven P., Goldberg, Alfred L.
Publicado 2014

Mammalian Ddi2 is a shuttling factor containing a retroviral protease domain that influences binding of ubiquitylated proteins and proteasomal degradation

por Collins, Galen Andrew, Sha, Zhe, Kuo, Chueh-Ling, Erbil, Beyza, Goldberg, Alfred L.
Publicado 2022

Immuno- and Constitutive Proteasomes Do Not Differ in Their Abilities to Degrade Ubiquitinated Proteins

por Nathan, James A., Spinnenhirn, Valentina, Schmidtke, Gunter, Basler, Michael, Groettrup, Marcus, Goldberg, Alfred L.
Publicado 2013

Inhibiting ubiquitination causes an accumulation of SUMOylated newly synthesized nuclear proteins at PML bodies

por Sha, Zhe, Blyszcz, Tamara, González-Prieto, Román, Vertegaal, Alfred C. O., Goldberg, Alfred L.
Publicado 2019

cGMP via PKG activates 26S proteasomes and enhances degradation of proteins, including ones that cause neurodegenerative diseases

por VerPlank, Jordan J. S., Tyrkalska, Sylwia D., Fleming, Angeleen, Rubinsztein, David C., Goldberg, Alfred L.
Publicado 2020

PDE1 inhibition facilitates proteasomal degradation of misfolded proteins and protects against cardiac proteinopathy

por Zhang, Hanming, Pan, Bo, Wu, Penglong, Parajuli, Nirmal, Rekhter, Mark D., Goldberg, Alfred L., Wang, Xuejun
Publicado 2019

The Internal Sequence of the Peptide-Substrate Determines Its N-Terminus Trimming by ERAP1

por Evnouchidou, Irini, Momburg, Frank, Papakyriakou, Athanasios, Chroni, Angeliki, Leondiadis, Leondios, Chang, Shih-Chung, Goldberg, Alfred L., Stratikos, Efstratios
Publicado 2008

Thiostrepton interacts covalently with Rpt subunits of the 19S proteasome and proteasome substrates

por Sandu, Cristinel, Chandramouli, Nagaranjan, Glickman, Joseph Fraser, Molina, Henrik, Kuo, Chueh-Ling, Kukushkin, Nikolay, Goldberg, Alfred L, Steller, Hermann
Publicado 2015

During muscle atrophy, thick, but not thin, filament components are degraded by MuRF1-dependent ubiquitylation

por Cohen, Shenhav, Brault, Jeffrey J., Gygi, Steven P., Glass, David J., Valenzuela, David M., Gartner, Carlos, Latres, Esther, Goldberg, Alfred L.
Publicado 2009

ClpX Is Essential and Activated by Single-Strand DNA Binding Protein in Mycobacteria

por Kester, Jemila C., Kandror, Olga, Akopian, Tatos, Chase, Michael R., Zhu, Junhao, Rubin, Eric J., Goldberg, Alfred L., Fortune, Sarah M.
Publicado 2021

Mycobacterium tuberculosis ClpP1 and ClpP2 Function Together in Protein Degradation and Are Required for Viability in vitro and During Infection

por Raju, Ravikiran M., Unnikrishnan, Meera, Rubin, Daniel H. F., Krishnamoorthy, Vidhya, Kandror, Olga, Akopian, Tatos N., Goldberg, Alfred L., Rubin, Eric J.
Publicado 2012