Exploring the In Vivo Role of the Mitochondrial Calcium Uniporter in Brown Fat Bioenergetics

por Flicker, Daniel, Sancak, Yasemin, Mick, Eran, Goldberger, Olga, Mootha, Vamsi K.
Publicado 2019

Evolutionary divergence reveals the molecular basis of EMRE dependence of the human MCU

por MacEwen, Melissa JS, Markhard, Andrew L, Bozbeyoglu, Mert, Bradford, Forrest, Goldberger, Olga, Mootha, Vamsi K, Sancak, Yasemin
Publicado 2020

Combinatorial GxGxE CRISPR screen identifies SLC25A39 in mitochondrial glutathione transport linking iron homeostasis to OXPHOS

por Shi, Xiaojian, Reinstadler, Bryn, Shah, Hardik, To, Tsz-Leung, Byrne, Katie, Summer, Luanna, Calvo, Sarah E., Goldberger, Olga, Doench, John G., Mootha, Vamsi K., Shen, Hongying
Publicado 2022

Hypoxia treatment reverses neurodegenerative disease in a mouse model of Leigh syndrome

por Ferrari, Michele, Jain, Isha H., Goldberger, Olga, Rezoagli, Emanuele, Thoonen, Robrecht, Cheng, Kai-Hung, Sosnovik, David E., Scherrer-Crosbie, Marielle, Mootha, Vamsi K., Zapol, Warren M.
Publicado 2017

Cardiovascular homeostasis dependence on MICU2, a regulatory subunit of the mitochondrial calcium uniporter

por Bick, Alexander G., Wakimoto, Hiroko, Kamer, Kimberli J., Sancak, Yasemin, Goldberger, Olga, Axelsson, Anna, DeLaughter, Daniel M., Gorham, Joshua M., Mootha, Vamsi K., Seidman, J. G., Seidman, Christine E.
Publicado 2017

Impaired hypoxic pulmonary vasoconstriction in a mouse model of Leigh syndrome

por Schleifer, Grigorij, Marutani, Eizo, Ferrari, Michele, Sharma, Rohit, Skinner, Owen, Goldberger, Olga, Grange, Robert Matthew Henry, Peneyra, Kathryn, Malhotra, Rajeev, Wepler, Martin, Ichinose, Fumito, Bloch, Donald B., Mootha, Vamsi K., Zapol, Warren M.
Publicado 2019

Mitochondrial dysfunction remodels one-carbon metabolism in human cells

por Bao, Xiaoyan Robert, Ong, Shao-En, Goldberger, Olga, Peng, Jun, Sharma, Rohit, Thompson, Dawn A, Vafai, Scott B, Cox, Andrew G, Marutani, Eizo, Ichinose, Fumito, Goessling, Wolfram, Regev, Aviv, Carr, Steven A, Clish, Clary B, Mootha, Vamsi K
Publicado 2016

Hepatic NADH reductive stress underlies common variation in metabolic traits

por Goodman, Russell P., Markhard, Andrew L., Shah, Hardik, Sharma, Rohit, Skinner, Owen S., Clish, Clary B., Deik, Amy, Patgiri, Anupam, Hsu, Yu-Han, Masia, Ricard, Noh, Hye Lim, Suk, Sujin, Goldberger, Olga, Hirschhorn, Joel, Yellen, Gary, Kim, Jason K., Mootha, Vamsi K.
Publicado 2020

High-throughput, pooled sequencing identifies mutations in NUBPL and FOXRED1 in human complex I deficiency

por Calvo, Sarah E, Tucker, Elena J, Compton, Alison G, Kirby, Denise M, Crawford, Gabriel, Burtt, Noel P, Rivas, Manuel A, Guiducci, Candace, Bruno, Damien L, Goldberger, Olga A, Redman, Michelle C, Wiltshire, Esko, Wilson, Callum J, Altshuler, David, Gabriel, Stacey B, Daly, Mark J, Thorburn, David R, Mootha, Vamsi K
Publicado 2010