Structural basis for the GTP specificity of the RNA kinase domain of fungal tRNA ligase

por Remus, Barbara S., Goldgur, Yehuda, Shuman, Stewart
Publicado 2017

Mycobacterial DNA polymerase I: activities and crystal structures of the POL domain as apoenzyme and in complex with a DNA primer-template and of the full-length FEN/EXO–POL enzyme...

por Ghosh, Shreya, Goldgur, Yehuda, Shuman, Stewart
Publicado 2020

Structure of 3′-PO(4)/5′-OH RNA ligase RtcB in complex with a 5′-OH oligonucleotide

por Banerjee, Ankan, Goldgur, Yehuda, Shuman, Stewart
Publicado 2021

Caveat mutator: alanine substitutions for conserved amino acids in RNA ligase elicit unexpected rearrangements of the active site for lysine adenylylation

por Unciuleac, Mihaela-Carmen, Goldgur, Yehuda, Shuman, Stewart
Publicado 2020

Distinctive structural basis for DNA recognition by the fission yeast Zn(2)Cys(6) transcription factor Pho7 and its role in phosphate homeostasis

por Garg, Angad, Goldgur, Yehuda, Schwer, Beate, Shuman, Stewart
Publicado 2018

Structure and two-metal mechanism of fungal tRNA ligase

por Banerjee, Ankan, Ghosh, Shreya, Goldgur, Yehuda, Shuman, Stewart
Publicado 2019

Atomic structures of the RNA end-healing 5′-OH kinase and 2′,3′-cyclic phosphodiesterase domains of fungal tRNA ligase: conformational switches in the kinase upon binding of the GT...

por Banerjee, Ankan, Goldgur, Yehuda, Schwer, Beate, Shuman, Stewart
Publicado 2019

Crystal structure and mutational analysis of Mycobacterium smegmatis FenA highlight active site amino acids and three metal ions essential for flap endonuclease and 5′ exonuclease...

por Uson, Maria Loressa, Carl, Ayala, Goldgur, Yehuda, Shuman, Stewart
Publicado 2018

Transcription of lncRNA prt, clustered prt RNA sites for Mmi1 binding, and RNA polymerase II CTD phospho-sites govern the repression of pho1 gene expression under phosphate-replete...

por Chatterjee, Debashree, Sanchez, Ana M., Goldgur, Yehuda, Shuman, Stewart, Schwer, Beate
Publicado 2016

In silico Driven Redesign of a Clinically Relevant Antibody for the Treatment of GD2 Positive Tumors

por Ahmed, Mahiuddin, Goldgur, Yehuda, Hu, Jian, Guo, Hong-Fen, Cheung, Nai-Kong V.
Publicado 2013

Structure of tRNA splicing enzyme Tpt1 illuminates the mechanism of RNA 2′-PO(4) recognition and ADP-ribosylation

por Banerjee, Ankan, Munir, Annum, Abdullahu, Leonora, Damha, Masad J., Goldgur, Yehuda, Shuman, Stewart
Publicado 2019

Structures of Fission Yeast Inositol Pyrophosphate Kinase Asp1 in Ligand-Free, Substrate-Bound, and Product-Bound States

por Benjamin, Bradley, Goldgur, Yehuda, Jork, Nikolaus, Jessen, Henning J., Schwer, Beate, Shuman, Stewart
Publicado 2022

Structure and mechanism of Mycobacterium smegmatis polynucleotide phosphorylase

por Unciuleac, Mihaela-Carmen, Ghosh, Shreya, de la Cruz, M. Jason, Goldgur, Yehuda, Shuman, Stewart
Publicado 2021

Structure of the EphB6 receptor ectodomain

por Mason, Emilia O., Goldgur, Yehuda, Robev, Dorothea, Freywald, Andrew, Nikolov, Dimitar B., Himanen, Juha P.
Publicado 2021

Conformational changes and loose packing promote E. coli Tryptophanase cold lability

por Kogan, Anna, Gdalevsky, Garik Y, Cohen-Luria, Rivka, Goldgur, Yehuda, Phillips, Robert S, Parola, Abraham H, Almog, Orna
Publicado 2009

Mechanism of glycoform specificity and in vivo protection by an anti-afucosylated IgG nanobody

por Gupta, Aaron, Kao, Kevin S., Yamin, Rachel, Oren, Deena A., Goldgur, Yehuda, Du, Jonathan, Lollar, Pete, Sundberg, Eric J., Ravetch, Jeffrey V.
Publicado 2023

Fully human monoclonal antibody targeting activated ADAM10 on colorectal cancer cells

por Saha, Nayanendu, Baek, Du-San, Mendoza, Rachelle P., Robev, Dorothea, Xu, Yan, Goldgur, Yehuda, De La Cruz, M. Jason, de Stanchina, Elisa, Janes, Peter W., Xu, Kai, Dimitrov, Dimiter S., Nikolov, Dimitar B.
Publicado 2023

Germline ETV6 Mutations Confer Susceptibility to Acute Lymphoblastic Leukemia and Thrombocytopenia

por Topka, Sabine, Vijai, Joseph, Walsh, Michael F., Jacobs, Lauren, Maria, Ann, Villano, Danylo, Gaddam, Pragna, Wu, Gang, McGee, Rose B., Quinn, Emily, Inaba, Hiroto, Hartford, Christine, Pui, Ching-hon, Pappo, Alberto, Edmonson, Michael, Zhang, Michael Y., Stepensky, Polina, Steinherz, Peter, Schrader, Kasmintan, Lincoln, Anne, Bussel, James, Lipkin, Steve M., Goldgur, Yehuda, Harit, Mira, Stadler, Zsofia K., Mullighan, Charles, Weintraub, Michael, Shimamura, Akiko, Zhang, Jinghui, Downing, James R., Nichols, Kim E., Offit, Kenneth
Publicado 2015

Small-molecule targeting of MUSASHI RNA-binding activity in acute myeloid leukemia

por Minuesa, Gerard, Albanese, Steven K., Xie, Wei, Kazansky, Yaniv, Worroll, Daniel, Chow, Arthur, Schurer, Alexandra, Park, Sun-Mi, Rotsides, Christina Z., Taggart, James, Rizzi, Andrea, Naden, Levi N., Chou, Timothy, Gourkanti, Saroj, Cappel, Daniel, Passarelli, Maria C., Fairchild, Lauren, Adura, Carolina, Glickman, J. Fraser, Schulman, Jessica, Famulare, Christopher, Patel, Minal, Eibl, Joseph K., Ross, Gregory M., Bhattacharya, Shibani, Tan, Derek S., Leslie, Christina S., Beuming, Thijs, Patel, Dinshaw J., Goldgur, Yehuda, Chodera, John D., Kharas, Michael G.
Publicado 2019

A Small-Molecule Pan-Id Antagonist Inhibits Pathologic Ocular Neovascularization

por Wojnarowicz, Paulina M., Silva, Raquel Lima e, Ohnaka, Masayuki, Lee, Sang Bae, Chin, Yvette, Kulukian, Anita, Chang, Sung-Hee, Desai, Bina, Escolano, Marta Garcia, Shah, Riddhi, Garcia-Cao, Marta, Xu, Sijia, Kadam, Rashmi, Goldgur, Yehuda, Miller, Meredith A., Ouerfelli, Ouathek, Yang, Guangli, Arakawa, Tsutomu, Albanese, Steven K., Garland, William A., Stoller, Glenn, Chaudhary, Jaideep, Norton, Larry, Soni, Rajesh Kumar, Philip, John, Hendrickson, Ronald C., Iavarone, Antonio, Dannenberg, Andrew J., Chodera, John D., Pavletich, Nikola, Lasorella, Anna, Campochiaro, Peter A., Benezra, Robert
Publicado 2019