Benzodiazepine Modulation of GABA(A) Receptors: A Mechanistic Perspective

por Goldschen-Ohm, Marcel P.
Publicado 2022

Unsupervised selection of optimal single-molecule time series idealization criterion

por Bandyopadhyay, Argha, Goldschen-Ohm, Marcel P.
Publicado 2021

The surprising difficulty of “simple” equilibrium binding measurements on ligand-gated ion channels

por Middendorf, Thomas R., Goldschen-Ohm, Marcel P.
Publicado 2022

A critical residue in the α(1)M2–M3 linker regulating mammalian GABA(A) receptor pore gating by diazepam

por Nors, Joseph W, Gupta, Shipra, Goldschen-Ohm, Marcel P
Publicado 2021

Evolutionarily conserved intracellular gate of voltage-dependent sodium channels

por Oelstrom, Kevin, Goldschen-Ohm, Marcel P., Holmgren, Miguel, Chanda, Baron
Publicado 2014

Top-down machine learning approach for high-throughput single-molecule analysis

por White, David S, Goldschen-Ohm, Marcel P, Goldsmith, Randall H, Chanda, Baron
Publicado 2020

Multiple pore conformations driven by asynchronous movements of voltage sensors in a eukaryotic sodium channel

por Goldschen-Ohm, Marcel P., Capes, Deborah L., Oelstrom, Kevin M., Chanda, Baron
Publicado 2013

A nonequilibrium binary elements-based kinetic model for benzodiazepine regulation of GABA(A) receptors

por Goldschen-Ohm, Marcel P., Haroldson, Alexander, Jones, Mathew V., Pearce, Robert A.
Publicado 2014

Domain IV voltage-sensor movement is both sufficient and rate limiting for fast inactivation in sodium channels

por Capes, Deborah L., Goldschen-Ohm, Marcel P., Arcisio-Miranda, Manoel, Bezanilla, Francisco, Chanda, Baron
Publicado 2013

The intrinsically liganded cyclic nucleotide–binding homology domain promotes KCNH channel activation

por Zhao, Yaxian, Goldschen-Ohm, Marcel P., Morais-Cabral, João H., Chanda, Baron, Robertson, Gail A.
Publicado 2017

Zinc activation of OTOP proton channels identifies structural elements of the gating apparatus

por Teng, Bochuan, Kaplan, Joshua P, Liang, Ziyu, Chyung, Kevin Saejin, Goldschen-Ohm, Marcel P, Liman, Emily R
Publicado 2023

Single-molecule imaging with cell-derived nanovesicles reveals early binding dynamics at a cyclic nucleotide-gated ion channel

por Patel, Vishal R., Salinas, Arturo M., Qi, Darong, Gupta, Shipra, Sidote, David J., Goldschen-Ohm, Marcel P.
Publicado 2021

Structure and dynamics underlying elementary ligand binding events in human pacemaking channels

por Goldschen-Ohm, Marcel P, Klenchin, Vadim A, White, David S, Cowgill, John B, Cui, Qiang, Goldsmith, Randall H, Chanda, Baron
Publicado 2016

Batrachotoxin acts as a stent to hold open homotetrameric prokaryotic voltage-gated sodium channels

por Finol-Urdaneta, Rocio K., McArthur, Jeffrey R., Goldschen-Ohm, Marcel P., Gaudet, Rachelle, Tikhonov, Denis B., Zhorov, Boris S., French, Robert J.
Publicado 2019