Structural Basis for Binding of Neutralizing Antibodies to Clostridioides difficile Binary Toxin

por Goldsmith, Jory A., Dewar, Vincent, Hermand, Philippe, Blais, Normand, McLellan, Jason S.
Publicado 2023

Structural basis for antibody binding to adenylate cyclase toxin reveals RTX linkers as neutralization-sensitive epitopes

por Goldsmith, Jory A., DiVenere, Andrea M., Maynard, Jennifer A., McLellan, Jason S.
Publicado 2021

Structural basis for non-canonical integrin engagement by Bordetella adenylate cyclase toxin

por Goldsmith, Jory A., DiVenere, Andrea M., Maynard, Jennifer A., McLellan, Jason S.
Publicado 2022

Bmal1 in the striatum influences alcohol intake in a sexually dimorphic manner

por de Zavalia, Nuria, Schoettner, Konrad, Goldsmith, Jory A., Solis, Pavel, Ferraro, Sarah, Parent, Gabrielle, Amir, Shimon
Publicado 2021

Blockade of the Adenylate Cyclase Toxin Synergizes with Opsonizing Antibodies to Protect Mice against Bordetella pertussis

por DiVenere, Andrea M., Amengor, Dzifa, Silva, Rui P., Goldsmith, Jory A., McLellan, Jason S., Maynard, Jennifer A.
Publicado 2022

Cryo-EM structure of the 2019-nCoV spike in the prefusion conformation

por Wrapp, Daniel, Wang, Nianshuang, Corbett, Kizzmekia S., Goldsmith, Jory A., Hsieh, Ching-Lin, Abiona, Olubukola, Graham, Barney S., McLellan, Jason S.
Publicado 2020

Cryo-EM Structure of the 2019-nCoV Spike in the Prefusion Conformation

por Wrapp, Daniel, Wang, Nianshuang, Corbett, Kizzmekia S., Goldsmith, Jory A., Hsieh, Ching-Lin, Abiona, Olubukola, Graham, Barney S., McLellan, Jason S.
Publicado 2020

A conserved tryptophan in the acylated segment of RTX toxins controls their β(2) integrin–independent cell penetration

por Osickova, Adriana, Knoblochova, Sarka, Bumba, Ladislav, Man, Petr, Kalaninova, Zuzana, Lepesheva, Anna, Jurnecka, David, Cizkova, Monika, Biedermannova, Lada, Goldsmith, Jory A., Maynard, Jennifer A., McLellan, Jason S., Osicka, Radim, Sebo, Peter, Masin, Jiri
Publicado 2023

Beyond Shielding: The Roles of Glycans in SARS-CoV-2 Spike Protein

por Casalino, Lorenzo, Gaieb, Zied, Goldsmith, Jory A., Hjorth, Christy K., Dommer, Abigail C., Harbison, Aoife M., Fogarty, Carl A., Barros, Emilia P., Taylor, Bryn C., McLellan, Jason S., Fadda, Elisa, Amaro, Rommie E.
Publicado 2020

Beyond Shielding: The Roles of Glycans in the SARS-CoV-2 Spike Protein

por Casalino, Lorenzo, Gaieb, Zied, Goldsmith, Jory A., Hjorth, Christy K., Dommer, Abigail C., Harbison, Aoife M., Fogarty, Carl A., Barros, Emilia P., Taylor, Bryn C., McLellan, Jason S., Fadda, Elisa, Amaro, Rommie E.
Publicado 2020

A glycan gate controls opening of the SARS-CoV-2 spike protein

por Sztain, Terra, Ahn, Surl-Hee, Bogetti, Anthony T., Casalino, Lorenzo, Goldsmith, Jory A., Seitz, Evan, McCool, Ryan S., Kearns, Fiona L., Acosta-Reyes, Francisco, Maji, Suvrajit, Mashayekhi, Ghoncheh, McCammon, J. Andrew, Ourmazd, Abbas, Frank, Joachim, McLellan, Jason S., Chong, Lillian T., Amaro, Rommie E.
Publicado 2021

A glycan gate controls opening of the SARS-CoV-2 spike protein

por Sztain, Terra, Ahn, Surl-Hee, Bogetti, Anthony T., Casalino, Lorenzo, Goldsmith, Jory A., Seitz, Evan, McCool, Ryan S., Kearns, Fiona L., Acosta-Reyes, Francisco, Maji, Suvrajit, Mashayekhi, Ghoncheh, McCammon, J. Andrew, Ourmazd, Abbas, Frank, Joachim, McLellan, Jason S., Chong, Lillian T., Amaro, Rommie E.
Publicado 2021

Stabilized coronavirus spike stem elicits a broadly protective antibody

por Hsieh, Ching-Lin, Werner, Anne P., Leist, Sarah R., Stevens, Laura J., Falconer, Ester, Goldsmith, Jory A., Chou, Chia-Wei, Abiona, Olubukola M., West, Ande, Westendorf, Kathryn, Muthuraman, Krithika, Fritch, Ethan J., Dinnon, Kenneth H., Schäfer, Alexandra, Denison, Mark R., Chappell, James D., Baric, Ralph S., Graham, Barney S., Corbett, Kizzmekia S., McLellan, Jason S.
Publicado 2021

Structure-based Design of Prefusion-stabilized SARS-CoV-2 Spikes

por Hsieh, Ching-Lin, Goldsmith, Jory A., Schaub, Jeffrey M., DiVenere, Andrea M., Kuo, Hung-Che, Javanmardi, Kamyab, Le, Kevin C., Wrapp, Daniel, Lee, Alison Gene-Wei, Liu, Yutong, Chou, Chia-Wei, Byrne, Patrick O., Hjorth, Christy K., Johnson, Nicole V., Ludes-Meyers, John, Nguyen, Annalee W., Park, Juyeon, Wang, Nianshuang, Amengor, Dzifa, Maynard, Jennifer A., Finkelstein, Ilya J., McLellan, Jason S.
Publicado 2020

Structure-based design of prefusion-stabilized SARS-CoV-2 spikes

por Hsieh, Ching-Lin, Goldsmith, Jory A., Schaub, Jeffrey M., DiVenere, Andrea M., Kuo, Hung-Che, Javanmardi, Kamyab, Le, Kevin C., Wrapp, Daniel, Lee, Alison G., Liu, Yutong, Chou, Chia-Wei, Byrne, Patrick O., Hjorth, Christy K., Johnson, Nicole V., Ludes-Meyers, John, Nguyen, Annalee W., Park, Juyeon, Wang, Nianshuang, Amengor, Dzifa, Lavinder, Jason J., Ippolito, Gregory C., Maynard, Jennifer A., Finkelstein, Ilya J., McLellan, Jason S.
Publicado 2020

The neutralizing antibody, LY-CoV555, protects against SARS-CoV-2 infection in nonhuman primates

por Jones, Bryan E., Brown-Augsburger, Patricia L., Corbett, Kizzmekia S., Westendorf, Kathryn, Davies, Julian, Cujec, Thomas P., Wiethoff, Christopher M., Blackbourne, Jamie L., Heinz, Beverly A., Foster, Denisa, Higgs, Richard E., Balasubramaniam, Deepa, Wang, Lingshu, Zhang, Yi, Yang, Eun Sung, Bidshahri, Roza, Kraft, Lucas, Hwang, Yuri, Žentelis, Stefanie, Jepson, Kevin R., Goya, Rodrigo, Smith, Maia A., Collins, David W., Hinshaw, Samuel J., Tycho, Sean A., Pellacani, Davide, Xiang, Ping, Muthuraman, Krithika, Sobhanifar, Solmaz, Piper, Marissa H., Triana, Franz J., Hendle, Jorg, Pustilnik, Anna, Adams, Andrew C., Berens, Shawn J., Baric, Ralph S., Martinez, David R., Cross, Robert W., Geisbert, Thomas W., Borisevich, Viktoriya, Abiona, Olubukola, Belli, Hayley M., de Vries, Maren, Mohamed, Adil, Dittmann, Meike, Samanovic, Marie I., Mulligan, Mark J., Goldsmith, Jory A., Hsieh, Ching-Lin, Johnson, Nicole V., Wrapp, Daniel, McLellan, Jason S., Barnhart, Bryan C., Graham, Barney S., Mascola, John R., Hansen, Carl L., Falconer, Ester
Publicado 2021