Regulatory roles of vertebrate Nocturnin: insights and remaining mysteries

por Hughes, Kelsey L., Abshire, Elizabeth T., Goldstrohm, Aaron C.
Publicado 2018

Chemi-Northern: a versatile chemiluminescent northern blot method for analysis and quantitation of RNA molecules

por McKenney, Katherine M., Connacher, Robert P., Dunshee, Elise B., Goldstrohm, Aaron C.
Publicado 2023

Combinatorial control of messenger RNAs by Pumilio, Nanos and Brain Tumor Proteins

por Arvola, René M., Weidmann, Chase A., Tanaka Hall, Traci M., Goldstrohm, Aaron C.
Publicado 2017

A conserved domain of Drosophila RNA-binding protein Pumilio interacts with multiple CCR4–NOT deadenylase complex subunits to repress target mRNAs

por Haugen, Rebecca J., Arvola, René M., Connacher, Robert P., Roden, Richard T., Goldstrohm, Aaron C.
Publicado 2022

The RNA binding domain of Pumilio antagonizes poly-adenosine binding protein and accelerates deadenylation

por Weidmann, Chase A., Raynard, Nathan A., Blewett, Nathan H., Van Etten, Jamie, Goldstrohm, Aaron C.
Publicado 2014

Unique repression domains of Pumilio utilize deadenylation and decapping factors to accelerate destruction of target mRNAs

por Arvola, René M, Chang, Chung-Te, Buytendorp, Joseph P, Levdansky, Yevgen, Valkov, Eugene, Freddolino, Peter L, Goldstrohm, Aaron C
Publicado 2020

The structure of human Nocturnin reveals a conserved ribonuclease domain that represses target transcript translation and abundance in cells

por Abshire, Elizabeth T, Chasseur, Jennifer, Bohn, Jennifer A, Del Rizzo, Paul A, Freddolino, Peter L, Goldstrohm, Aaron C, Trievel, Raymond C
Publicado 2018

Drosophila Nanos acts as a molecular clamp that modulates the RNA-binding and repression activities of Pumilio

por Weidmann, Chase A, Qiu, Chen, Arvola, René M, Lou, Tzu-Fang, Killingsworth, Jordan, Campbell, Zachary T, Tanaka Hall, Traci M, Goldstrohm, Aaron C
Publicado 2016

Identification of diverse target RNAs that are functionally regulated by human Pumilio proteins

por Bohn, Jennifer A, Van Etten, Jamie L, Schagat, Trista L, Bowman, Brittany M, McEachin, Richard C, Freddolino, Peter L, Goldstrohm, Aaron C
Publicado 2018

Principles of mRNA control by human PUM proteins elucidated from multimodal experiments and integrative data analysis

por Wolfe, Michael B., Schagat, Trista L., Paulsen, Michelle T., Magnuson, Brian, Ljungman, Mats, Park, Daeyoon, Zhang, Chi, Campbell, Zachary T., Goldstrohm, Aaron C., Freddolino, Peter L.
Publicado 2020

Ribosome queuing enables non-AUG translation to be resistant to multiple protein synthesis inhibitors

por Kearse, Michael G., Goldman, Daniel H., Choi, Jiou, Nwaezeapu, Chike, Liang, Dongming, Green, Katelyn M., Goldstrohm, Aaron C., Todd, Peter K., Green, Rachel, Wilusz, Jeremy E.
Publicado 2019

RAN translation at C9orf72-associated repeat expansions is selectively enhanced by the integrated stress response

por Green, Katelyn M., Glineburg, M. Rebecca, Kearse, Michael G., Flores, Brittany N., Linsalata, Alexander E., Fedak, Stephen J., Goldstrohm, Aaron C., Barmada, Sami J., Todd, Peter K.
Publicado 2017

Human Pumilio proteins directly bind the CCR4-NOT deadenylase complex to regulate the transcriptome

por Enwerem, Isioma I.I., Elrod, Nathan D., Chang, Chung-Te, Lin, Ai, Ji, Ping, Bohn, Jennifer A., Levdansky, Yevgen, Wagner, Eric J., Valkov, Eugene, Goldstrohm, Aaron C.
Publicado 2021

Regulation of the Drosophila transcriptome by Pumilio and CCR4-NOT deadenylase

por Haugen, Rebecca J., Barnier, Catherine, Elrod, Nathan D., Luo, Hua, Jensen, Madeline K., Ji, Ping, Smibert, Craig A., Lipshitz, Howard D., Wagner, Eric J., Lydia Freddolino, P., Goldstrohm, Aaron C.
Publicado 2023