A Screening Pipeline for Antiparasitic Agents Targeting Cryptosporidium Inosine Monophosphate Dehydrogenase

por Sharling, Lisa, Liu, Xiaoping, Gollapalli, Deviprasad R., Maurya, Sushil K., Hedstrom, Lizbeth, Striepen, Boris
Publicado 2010

Structure of Cryptosporidium IMP dehydrogenase bound to an inhibitor with in vivo antiparasitic activity

por Kim, Youngchang, Makowska-Grzyska, Magdalena, Gorla, Suresh Kumar, Gollapalli, Deviprasad R., Cuny, Gregory D., Joachimiak, Andrzej, Hedstrom, Lizbeth
Publicado 2015

A Novel Cofactor-binding Mode in Bacterial IMP Dehydrogenases Explains Inhibitor Selectivity

por Makowska-Grzyska, Magdalena, Kim, Youngchang, Maltseva, Natalia, Osipiuk, Jerzy, Gu, Minyi, Zhang, Minjia, Mandapati, Kavitha, Gollapalli, Deviprasad R., Gorla, Suresh Kumar, Hedstrom, Lizbeth, Joachimiak, Andrzej
Publicado 2015

Cofactor mobility determines reaction outcome in the IMPDH/GMPR (β/α)(8) barrel enzymes

por Patton, Gregory C., Stenmark, Pål, Gollapalli, Deviprasad R., Sevastik, Robin, Kursula, Petri, Flodin, Susanne, Schuler, Herwig, Swales, Colin T., Eklund, Hans, Himo, Fahmi, Nordlund, Pär, Hedstrom, Lizbeth
Publicado 2011

Synthesis, in Vitro Evaluation and Cocrystal Structure of 4-Oxo-[1]benzopyrano[4,3-c]pyrazole Cryptosporidium parvum Inosine 5′-Monophosphate Dehydrogenase (CpIMPDH) Inhibitors

por Sun, Zhuming, Khan, Jihan, Makowska-Grzyska, Magdalena, Zhang, Minjia, Cho, Joon Hyung, Suebsuwong, Chalada, Vo, Pascal, Gollapalli, Deviprasad R., Kim, Youngchang, Joachimiak, Andrzej, Hedstrom, Lizbeth, Cuny, Gregory D.
Publicado 2014