Alzheimer’s disease-related dysregulation of mRNA translation causes key pathological features with ageing

por Ghosh, Anshua, Mizuno, Keiko, Tiwari, Sachin S., Proitsi, Petroula, Gomez Perez-Nievas, Beatriz, Glennon, Elizabeth, Martinez-Nunez, Rocio T., Giese, K. Peter
Publicado 2020

Direct Keap1-Nrf2 disruption as a potential therapeutic target for Alzheimer’s disease

por Kerr, Fiona, Sofola-Adesakin, Oyinkan, Ivanov, Dobril K., Gatliff, Jemma, Gomez Perez-Nievas, Beatriz, Bertrand, Hélène C., Martinez, Pedro, Callard, Rebecca, Snoeren, Inge, Cochemé, Helena M., Adcott, Jennifer, Khericha, Mobina, Castillo-Quan, Jorge Iván, Wells, Geoffrey, Noble, Wendy, Thornton, Janet, Partridge, Linda
Publicado 2017

TREM2 shedding by cleavage at the H157‐S158 bond is accelerated for the Alzheimer's disease‐associated H157Y variant

por Thornton, Peter, Sevalle, Jean, Deery, Michael J, Fraser, Graham, Zhou, Ye, Ståhl, Sara, Franssen, Elske H, Dodd, Roger B, Qamar, Seema, Gomez Perez‐Nievas, Beatriz, Nicol, Louise SC, Eketjäll, Susanna, Revell, Jefferson, Jones, Clare, Billinton, Andrew, St George‐Hyslop, Peter H, Chessell, Iain, Crowther, Damian C
Publicado 2017