Empirical Validation of a Hypothesis of the Hormetic Selective Forces Driving the Evolution of Longevity Regulation Mechanisms

por Gomez-Perez, Alejandra, Kyryakov, Pavlo, Burstein, Michelle T., Asbah, Nimara, Noohi, Forough, Iouk, Tania, Titorenko, Vladimir I.
Publicado 2016

Caloric restriction delays yeast chronological aging by remodeling carbohydrate and lipid metabolism, altering peroxisomal and mitochondrial functionalities, and postponing the ons...

por Arlia-Ciommo, Anthony, Leonov, Anna, Beach, Adam, Richard, Vincent R., Bourque, Simon D., Burstein, Michelle T., Kyryakov, Pavlo, Gomez-Perez, Alejandra, Koupaki, Olivia, Feldman, Rachel, Titorenko, Vladimir I.
Publicado 2018

Mechanisms through which lithocholic acid delays yeast chronological aging under caloric restriction conditions

por Arlia-Ciommo, Anthony, Leonov, Anna, Mohammad, Karamat, Beach, Adam, Richard, Vincent R., Bourque, Simon D., Burstein, Michelle T., Goldberg, Alexander A., Kyryakov, Pavlo, Gomez-Perez, Alejandra, Koupaki, Olivia, Titorenko, Vladimir I.
Publicado 2018

Macromitophagy is a longevity assurance process that in chronologically aging yeast limited in calorie supply sustains functional mitochondria and maintains cellular lipid homeosta...

por Richard, Vincent R., Leonov, Anna, Beach, Adam, Burstein, Michelle T., Koupaki, Olivia, Gomez-Perez, Alejandra, Levy, Sean, Pluska, Lukas, Mattie, Sevan, Rafeh, Rami, Iouk, Tatiana, Sheibani, Sara, Greenwood, Michael, Vali, Hojatollah, Titorenko, Vladimir I.
Publicado 2013