Adeno-associated virus: from defective virus to effective vector

por Gonçalves, Manuel AFV
Publicado 2005

AAV-vectored base editor trans-splicing delivers dystrophin repair

por Li, Zhen, Gonçalves, Manuel A.F.V.
Publicado 2023

DNA, RNA, and Protein Tools for Editing the Genetic Information in Human Cells

por Chen, Xiaoyu, Gonçalves, Manuel A.F.V.
Publicado 2018

Adenoviral Vectors Meet Gene Editing: A Rising Partnership for the Genomic Engineering of Human Stem Cells and Their Progeny

por Tasca, Francesca, Wang, Qian, Gonçalves, Manuel A.F.V.
Publicado 2020

A primer to gene therapy: Progress, prospects, and problems

por Zittersteijn, Hidde A., Gonçalves, Manuel A.F.V., Hoeben, Rob C.
Publicado 2020

The Chromatin Structure Differentially Impacts High-Specificity CRISPR-Cas9 Nuclease Strategies

por Chen, Xiaoyu, Liu, Jin, Janssen, Josephine M., Gonçalves, Manuel A.F.V.
Publicado 2017

The Chromatin Structure of CRISPR-Cas9 Target DNA Controls the Balance between Mutagenic and Homology-Directed Gene-Editing Events

por Janssen, Josephine M., Chen, Xiaoyu, Liu, Jin, Gonçalves, Manuel A.F.V.
Publicado 2019

High-capacity adenovector delivery of forced CRISPR-Cas9 heterodimers fosters precise chromosomal deletions in human cells

por Tasca, Francesca, Brescia, Marcella, Liu, Jin, Janssen, Josephine M., Mamchaoui, Kamel, Gonçalves, Manuel A.F.V.
Publicado 2023

Probing the impact of chromatin conformation on genome editing tools

por Chen, Xiaoyu, Rinsma, Marrit, Janssen, Josephine M., Liu, Jin, Maggio, Ignazio, Gonçalves, Manuel A.F.V.
Publicado 2016

Selection-free gene repair after adenoviral vector transduction of designer nucleases: rescue of dystrophin synthesis in DMD muscle cell populations

por Maggio, Ignazio, Stefanucci, Luca, Janssen, Josephine M., Liu, Jin, Chen, Xiaoyu, Mouly, Vincent, Gonçalves, Manuel A.F.V.
Publicado 2016

Efficient and scalable generation of primordial germ cells in 2D culture using basement membrane extract overlay

por Overeem, Arend W., Chang, Yolanda W., Moustakas, Ioannis, Roelse, Celine M., Hillenius, Sanne, Helm, Talia Van Der, Schrier, Valérie F. Van Der, Gonçalves, Manuel A.F.V., Mei, Hailiang, Freund, Christian, Chuva de Sousa Lopes, Susana M.
Publicado 2023

Progress and harmonization of gene editing to treat human diseases: Proceeding of COST Action CA21113 GenE-HumDi

por Cavazza, Alessia, Hendel, Ayal, Bak, Rasmus O., Rio, Paula, Güell, Marc, Lainšček, Duško, Arechavala-Gomeza, Virginia, Peng, Ling, Hapil, Fatma Zehra, Harvey, Joshua, Ortega, Francisco G., Gonzalez-Martinez, Coral, Lederer, Carsten W., Mikkelsen, Kasper, Gasiunas, Giedrius, Kalter, Nechama, Gonçalves, Manuel A.F.V., Petersen, Julie, Garanto, Alejandro, Montoliu, Lluis, Maresca, Marcello, Seemann, Stefan E., Gorodkin, Jan, Mazini, Loubna, Sanchez, Rosario, Rodriguez-Madoz, Juan R., Maldonado-Pérez, Noelia, Laura, Torella, Schmueck-Henneresse, Michael, Maccalli, Cristina, Grünewald, Julian, Carmona, Gloria, Kachamakova-Trojanowska, Neli, Miccio, Annarita, Martin, Francisco, Turchiano, Giandomenico, Cathomen, Toni, Luo, Yonglun, Tsai, Shengdar Q., Benabdellah, Karim
Publicado 2023