Epoxy-α-lapachone (2,2-Dimethyl-3,4-dihydro-spiro[2H-naphtho[2,3-b]pyran-10,2′-oxirane]-5(10H)-one): a promising molecule to control infections caused by protozoan parasites

por Peixoto, Juliana Figueiredo, Oliveira, Adriane da Silva, Gonçalves - Oliveira, Luiz Filipe, Souza - Silva, Franklin, Alves, Carlos Roberto
Publicado 2023

In Silico Insights into the Mechanism of Action of Epoxy-α-Lapachone and Epoxymethyl-Lawsone in Leishmania spp.

por Peixoto, Juliana Figueiredo, Oliveira, Adriane da Silva, Monteiro, Patrícia Queiroz, Gonçalves-Oliveira, Luiz Filipe, Andrade-Neto, Valter Viana, Ferreira, Vitor Francisco, Souza-Silva, Franklin, Alves, Carlos Roberto
Publicado 2021

The combination therapy of meglumine antimoniate and oxiranes (epoxy-α-lapachone and epoxymethyl-lawsone) enhance the leishmanicidal effect in mice infected by Leishmania (Leishman...

por Gonçalves-Oliveira, Luiz Filipe, Souza-Silva, Franklin, de Castro Côrtes, Luzia Monteiro, Veloso, Laura Barral, Santini Pereira, Bernardo Acácio, Cysne-Finkelstein, Lea, Lechuga, Guilherme Curty, Bourguignon, Saulo Cabral, Almeida-Souza, Fernando, da Silva Calabrese, Kátia, Ferreira, Vitor Francisco, Alves, Carlos Roberto
Publicado 2019