The mechanism of MYB transcriptional regulation by MLL-AF9 oncoprotein

por Cao, Lu, Mitra, Partha, Gonda, Thomas J.
Publicado 2019

MYB suppresses differentiation and apoptosis of human breast cancer cells

por Drabsch, Yvette, Robert, Ramsay G, Gonda, Thomas J
Publicado 2010

Estrogen receptor-α recruits P-TEFb to overcome transcriptional pausing in intron 1 of the MYB gene

por Mitra, Partha, Pereira, Lloyd A., Drabsch, Yvette, Ramsay, Robert G., Gonda, Thomas J.
Publicado 2012

CDK9 inhibitors selectively target estrogen receptor-positive breast cancer cells through combined inhibition of MYB and MCL-1 expression

por Mitra, Partha, Yang, Ren-Ming, Sutton, James, Ramsay, Robert G., Gonda, Thomas J.
Publicado 2016

PG545, a dual heparanase and angiogenesis inhibitor, induces potent anti-tumour and anti-metastatic efficacy in preclinical models

por Dredge, K, Hammond, E, Handley, P, Gonda, T J, Smith, M T, Vincent, C, Brandt, R, Ferro, V, Bytheway, I
Publicado 2011

Myb-Binding Protein 1A (MYBBP1A) Is Essential for Early Embryonic Development, Controls Cell Cycle and Mitosis, and Acts as a Tumor Suppressor

por Mori, Silvia, Bernardi, Rosa, Laurent, Audrey, Resnati, Massimo, Crippa, Ambra, Gabrieli, Arianna, Keough, Rebecca, Gonda, Thomas J., Blasi, Francesco
Publicado 2012

Generation of a Genome Scale Lentiviral Vector Library for EF1α Promoter-Driven Expression of Human ORFs and Identification of Human Genes Affecting Viral Titer

por Škalamera, Dubravka, Dahmer, Mareike, Purdon, Amy S., Wilson, Benjamin M., Ranall, Max V., Blumenthal, Antje, Gabrielli, Brian, Gonda, Thomas J.
Publicado 2012

Integrated genome-wide chromatin occupancy and expression analyses identify key myeloid pro-differentiation transcription factors repressed by Myb

por Zhao, Liang, Glazov, Evgeny A., Pattabiraman, Diwakar R., Al-Owaidi, Faisal, Zhang, Ping, Brown, Matthew A., Leo, Paul J., Gonda, Thomas J.
Publicado 2011

Assessment of CXC ligand 12-mediated calcium signalling and its regulators in basal-like breast cancer cells

por Jamaludin, S. Y. N., Azimi, I., Davis, F. M., Peters, A. A., Gonda, T. J., Thompson, E. W., Roberts-Thomson, S. J., Monteith, G. R.
Publicado 2018

Partial reprogramming of heterologous cells by defined factors to generate megakaryocyte lineage-restricted biomolecules

por Artuz, Crisbel M., Knights, Alexander J., Funnell, Alister P.W., Gonda, Thomas J., Ravid, Katya, Pearson, Richard C.M., Quinlan, Kate G.R., Crossley, Merlin
Publicado 2018

A High-Throughput Platform for Lentiviral Overexpression Screening of the Human ORFeome

por Škalamera, Dubravka, Ranall, Max V., Wilson, Benjamin M., Leo, Paul, Purdon, Amy S., Hyde, Carolyn, Nourbakhsh, Ehsan, Grimmond, Sean M., Barry, Simon C., Gabrielli, Brian, Gonda, Thomas J.
Publicado 2011

MYB Elongation Is Regulated by the Nucleic Acid Binding of NFκB p50 to the Intronic Stem-Loop Region

por Pereira, Lloyd A., Hugo, Honor J., Malaterre, Jordane, Huiling, Xu, Sonza, Secondo, Cures, Alina, Purcell, Damian F. J., Ramsland, Paul A., Gerondakis, Steven, Gonda, Thomas J., Ramsay, Robert G.
Publicado 2015

Direct repression of MYB by ZEB1 suppresses proliferation and epithelial gene expression during epithelial-to-mesenchymal transition of breast cancer cells

por Hugo, Honor J, Pereira, Lloyd, Suryadinata, Randy, Drabsch, Yvette, Gonda, Thomas J, Gunasinghe, N P A Devika, Pinto, Cletus, Soo, Eliza TL, van Denderen, Bryce JW, Hill, Prue, Ramsay, Robert G, Sarcevic, Boris, Newgreen, Donald F, Thompson, Erik W
Publicado 2013

Genome-wide gain-of-function screen for genes that induce epithelial-to-mesenchymal transition in breast cancer

por Škalamera, Dubravka, Dahmer-Heath, Mareike, Stevenson, Alexander J., Pinto, Cletus, Shah, Esha T., Daignault, Sheena M., Said, Nur Akmarina B.M., Davis, Melissa, Haass, Nikolas K., Williams, Elizabeth D., Hollier, Brett G., Thompson, Erik W., Gabrielli, Brian, Gonda, Thomas J.
Publicado 2016

C/EBPβ is a MYB- and p300-cooperating pro-leukemogenic factor and promising drug target in acute myeloid leukemia

por Yusenko, Maria V., Trentmann, Amke, Casolari, Debora A., Abdel Ghani, Luca, Lenz, Mairin, Horn, Melanie, Dörner, Wolfgang, Klempnauer, Stefan, Mootz, Henning D., Arteaga, Maria Francisca, Mikesch, Jan-Henrik, D’Andrea, Richard J., Gonda, Thomas J., Müller-Tidow, Carsten, Schmidt, Thomas J., Klempnauer, Karl-Heinz
Publicado 2021

Rare variants in Fanconi anemia genes are enriched in acute myeloid leukemia

por Maung, Kyaw Ze Ya, Leo, Paul J., Bassal, Mahmoud, Casolari, Debora A., Gray, James X, Bray, Sarah C., Pederson, Stephen, Singhal, Deepak, Samaraweera, Saumya E., Nguyen, Tran, Cildir, Gökhan, Marshall, Mhairi, Ewing, Adam, Duncan, Emma L., Brown, Matthew A., Saal, Russell, Tergaonkar, Vinay, To, Luen Bik, Marlton, Paula, Gill, Devinder, Lewis, Ian, Deans, Andrew J, Brown, Anna L, D’Andrea, Richard J, Gonda, Thomas J
Publicado 2018

Germline mutations in mitochondrial complex I reveal genetic and targetable vulnerability in IDH1-mutant acute myeloid leukaemia

por Bassal, Mahmoud A., Samaraweera, Saumya E., Lim, Kelly, Benard, Brooks A., Bailey, Sheree, Kaur, Satinder, Leo, Paul, Toubia, John, Thompson-Peach, Chloe, Nguyen, Tran, Maung, Kyaw Ze Ya, Casolari, Debora A., Iarossi, Diana G., Pagani, Ilaria S., Powell, Jason, Pitson, Stuart, Natera, Siria, Roessner, Ute, Lewis, Ian D., Brown, Anna L., Tenen, Daniel G., Robinson, Nirmal, Ross, David M., Majeti, Ravindra, Gonda, Thomas J., Thomas, Daniel, D’Andrea, Richard J.
Publicado 2022

Author Correction: Germline mutations in mitochondrial complex I reveal genetic and targetable vulnerability in IDH1-mutant acute myeloid leukaemia

por Bassal, Mahmoud A., Samaraweera, Saumya E., Lim, Kelly, Benard, Brooks A., Bailey, Sheree, Kaur, Satinder, Leo, Paul, Toubia, John, Thompson-Peach, Chloe, Nguyen, Tran, Maung, Kyaw Ze Ya, Casolari, Debora A., Iarossi, Diana G., Pagani, Ilaria S., Powell, Jason, Pitson, Stuart, Natera, Siria, Roessner, Ute, Lewis, Ian D., Brown, Anna L., Tenen, Daniel G., Robinson, Nirmal, Ross, David M., Majeti, Ravindra, Gonda, Thomas J., Thomas, Daniel, D’Andrea, Richard J.
Publicado 2022

Nuclear stabilization of p53 requires a functional nucleolar surveillance pathway

por Hannan, Katherine M., Soo, Priscilla, Wong, Mei S., Lee, Justine K., Hein, Nadine, Poh, Perlita, Wysoke, Kira D., Williams, Tobias D., Montellese, Christian, Smith, Lorey K., Al-Obaidi, Sheren J., Núñez-Villacís, Lorena, Pavy, Megan, He, Jin-Shu, Parsons, Kate M., Loring, Karagh E., Morrison, Tess, Diesch, Jeannine, Burgio, Gaetan, Ferreira, Rita, Feng, Zhi-Ping, Gould, Cathryn M., Madhamshettiwar, Piyush B., Flygare, Johan, Gonda, Thomas J., Simpson, Kaylene J., Kutay, Ulrike, Pearson, Richard B., Engel, Christoph, Watkins, Nicholas J., Hannan, Ross D., George, Amee J.
Publicado 2022