Specific knockdown of uPA/uPAR attenuates invasion in glioblastoma cells and xenografts by inhibition of cleavage and trafficking of Notch -1 receptor

por Raghu, Hari, Gondi, Christopher S, Dinh, Dzung H, Gujrati, Meena, Rao, Jasti S
Publicado 2011

Localization of uPAR and MMP-9 in lipid rafts is critical for migration, invasion and angiogenesis in human breast cancer cells

por Raghu, Hari, Sodadasu, Prasanna Kumar, Malla, Rama Rao, Gondi, Christopher S, Estes, Norman, Rao, Jasti S
Publicado 2010

Suppression of uPA and uPAR Attenuates Angiogenin Mediated Angiogenesis in Endothelial and Glioblastoma Cell Lines

por Raghu, Hari, Lakka, Sajani S., Gondi, Christopher S., Mohanam, Sanjeeva, Dinh, Dzung H., Gujrati, Meena, Rao, Jasti S.
Publicado 2010

SPARC Overexpression Inhibits Cell Proliferation in Neuroblastoma and Is Partly Mediated by Tumor Suppressor Protein PTEN and AKT

por Bhoopathi, Praveen, Gorantla, Bharathi, Sailaja, G. S., Gondi, Christopher S., Gujrati, Meena, Klopfenstein, Jeffrey D., Rao, Jasti S.
Publicado 2012

Apoptosis Induced by Knockdown of uPAR and MMP-9 is Mediated by Inactivation of EGFR/STAT3 Signaling in Medulloblastoma

por Kotipatruni, Ramaprasada Rao, Nalla, Arun Kumar, Asuthkar, Swapna, Gondi, Christopher S., Dinh, Dzung H., Rao, Jasti S.
Publicado 2012

Chronic radiation exposure of neuroblastoma cells reduces nMYC copy number

por Gnanamony, Manu, Antony, Reuben, Fernández, Karen S., Jaime, Libes, Lin, Julian, Joseph, Pushpa A., Gondi, Christopher S.
Publicado 2017

Circular dumbbell miR-34a-3p and −5p suppresses pancreatic tumor cell-induced angiogenesis and activates macrophages

por Gnanamony, Manu, Demirkhanyan, Lusine, Ge, Liang, Sojitra, Paresh, Bapana, Sneha, Norton, Joseph A., Gondi, Christopher S.
Publicado 2021

Cathepsin B and uPAR Knockdown Inhibits Tumor-induced Angiogenesis by Modulating VEGF Expression in Glioma

por Malla, Rama Rao, Gopinath, Sreelatha, Gondi, Christopher S., Alapati, Kiranmai, Dinh, Dzung H., Gujrati, Meena, Rao, Jasti S.
Publicado 2011

SPARC overexpression combined with radiation retards angiogenesis by suppressing VEGF-A via miR-410 in human neuroblastoma cells

por Boyineni, Jerusha, Tanpure, Smita, Gnanamony, Manu, Antony, Reuben, Fernández, Karen S., Lin, Julian, Pinson, David, Gondi, Christopher S.
Publicado 2016

Downregulation of uPAR and Cathepsin B Induces Apoptosis via Regulation of Bcl-2 and Bax and Inhibition of the PI3K/Akt Pathway in Gliomas

por Malla, Ramarao, Gopinath, Sreelatha, Alapati, Kiranmai, Gondi, Christopher S., Gujrati, Meena, Dinh, Dzung H., Mohanam, Sanjeeva, Rao, Jasti S.
Publicado 2010

Correction: Downregulation of uPAR and Cathepsin B Induces Apoptosis via Regulation of Bcl-2 and Bax and Inhibition of the PI3K/Akt Pathway in Gliomas

por Malla, Ramarao, Gopinath, Sreelatha, Alapati, Kiranmai, Gondi, Christopher S., Gujrati, Meena, Dinh, Dzung H., Mohanam, Sanjeeva, Rao, Jasti S.
Publicado 2014

Regulation of Glioblastoma Progression by Cord Blood Stem Cells Is Mediated by Downregulation of Cyclin D1

por Velpula, Kiran Kumar, Dasari, Venkata Ramesh, Tsung, Andrew J., Gondi, Christopher S., Klopfenstein, Jeffrey D., Mohanam, Sanjeeva, Rao, Jasti S.
Publicado 2011

The secreted protein acidic and rich in cysteine (SPARC) induces endoplasmic reticulum stress leading to autophagy-mediated apoptosis in neuroblastoma

por SAILAJA, G.S., BHOOPATHI, PRAVEEN, GORANTLA, BHARATHI, CHETTY, CHANDRAMU, GOGINENI, VENKATESWARA RAO, VELPULA, KIRAN KUMAR, GONDI, CHRISTOPHER S., RAO, JASTI S.
Publicado 2012

Multifunctional roles of urokinase plasminogen activator (uPA) in cancer stemness and chemoresistance of pancreatic cancer

por Asuthkar, Swapna, Stepanova, Victoria, Lebedeva, Tatiana, Holterman, AiXuan L., Estes, Norman, Cines, Douglas B., Rao, Jasti S., Gondi, Christopher S.
Publicado 2013

Co-Depletion of Cathepsin B and uPAR Induces G0/G1 Arrest in Glioma via FOXO3a Mediated p27(Kip1) Upregulation

por Gopinath, Sreelatha, Malla, Rama Rao, Gondi, Christopher S., Alapati, Kiranmai, Fassett, Daniel, Klopfenstein, Jeffrey D., Dinh, Dzung H., Gujrati, Meena, Rao, Jasti S.
Publicado 2010

SPARC overexpression suppresses radiation-induced HSP27 and induces the collapse of mitochondrial Δψ in neuroblastoma cells

por Tanpure, Smita, Boyineini, Jerusha, Gnanamony, Manu, Antony, Reuben, Fernández, Karen S., Libes, Jaime, Lin, Julian, Pinson, David, Joseph, Pushpa A., Gondi, Christopher S.
Publicado 2017

MMP-9, uPAR and Cathepsin B Silencing Downregulate Integrins in Human Glioma Xenograft Cells In Vitro and In Vivo in Nude Mice

por Veeravalli, Krishna Kumar, Chetty, Chandramu, Ponnala, Shivani, Gondi, Christopher S., Lakka, Sajani S., Fassett, Daniel, Klopfenstein, Jeffrey D., Dinh, Dzung H., Gujrati, Meena, Rao, Jasti S.
Publicado 2010