The Chemically-Modified Tetracycline COL-3 and Its Parent Compound Doxycycline Prevent Microglial Inflammatory Responses by Reducing Glucose-Mediated Oxidative Stress

por Ferreira Junior, Nilson Carlos, dos Santos Pereira, Maurício, Francis, Nour, Ramirez, Paola, Martorell, Paula, González-Lizarraga, Florencia, Figadère, Bruno, Chehin, Rosana, Del Bel, Elaine, Raisman-Vozari, Rita, Michel, Patrick Pierre
Publicado 2021

CMT-3 targets different α-synuclein aggregates mitigating their toxic and inflammogenic effects

por González-Lizárraga, Florencia, Ploper, Diego, Ávila, César L., Socías, Sergio B., dos-Santos-Pereira, Mauricio, Machín, Belén, Del-Bel, Elaine, Michel, Patrick Pierre, Pietrasanta, Lía I., Raisman-Vozari, Rita, Chehín, Rosana
Publicado 2020

Rifampicin and Its Derivative Rifampicin Quinone Reduce Microglial Inflammatory Responses and Neurodegeneration Induced In Vitro by α-Synuclein Fibrillary Aggregates

por Acuña, Leonardo, Hamadat, Sabah, Corbalán, Natalia S., González-Lizárraga, Florencia, dos-Santos-Pereira, Mauricio, Rocca, Jérémy, Sepúlveda Díaz, Julia, Del-Bel, Elaine, Papy-García, Dulce, Chehín, Rosana N., Michel, Patrick P., Raisman-Vozari, Rita
Publicado 2019

Rescue of Dopamine Neurons from Iron-Dependent Ferroptosis by Doxycycline and Demeclocycline and Their Non-Antibiotic Derivatives

por Tourville, Aurore, Viguier, Sarah, González-Lizárraga, Florencia, Tomas-Grau, Rodrigo Hernán, Ramirez, Paola, Brunel, Jean-Michel, Dos Santos Pereira, Mauricio, Del-Bel, Elaine, Chehin, Rosana, Ferrié, Laurent, Raisman-Vozari, Rita, Figadère, Bruno, Michel, Patrick Pierre
Publicado 2023

Doxycycline Interferes With Tau Aggregation and Reduces Its Neuronal Toxicity

por Medina, Luciana, González-Lizárraga, Florencia, Dominguez-Meijide, Antonio, Ploper, Diego, Parrales, Valeria, Sequeira, Sabrina, Cima-Omori, Maria-Sol, Zweckstetter, Markus, Del Bel, Elaine, Michel, Patrick P., Outeiro, Tiago Fleming, Raisman-Vozari, Rita, Chehín, Rosana, Socias, Sergio B.
Publicado 2021

Repurposing doxycycline for synucleinopathies: remodelling of α-synuclein oligomers towards non-toxic parallel beta-sheet structured species

por González-Lizárraga, Florencia, Socías, Sergio B., Ávila, César L., Torres-Bugeau, Clarisa M., Barbosa, Leandro R. S., Binolfi, Andres, Sepúlveda-Díaz, Julia E., Del-Bel, Elaine, Fernandez, Claudio O., Papy-Garcia, Dulce, Itri, Rosangela, Raisman-Vozari, Rita, Chehín, Rosana N.
Publicado 2017

Neuroprotective Effects of a Novel Demeclocycline Derivative Lacking Antibiotic Activity: From a Hit to a Promising Lead Compound

por Tomas-Grau, Rodrigo, González-Lizárraga, Florencia, Ploper, Diego, Avila, César L., Socías, Sergio B., Besnault, Pierre, Tourville, Aurore, Mella, Rosa M., Villacé, Patricia, Salado, Clarisa, Rose, Clémence, Seon-Méniel, Blandine, Brunel, Jean-Michel, Ferrié, Laurent, Raisman-Vozari, Rita, Michel, Patrick P., Figadère, Bruno, Chehín, Rosana
Publicado 2022