Modelling inner ear development and disease using pluripotent stem cells – a pathway to new therapeutic strategies

por Connolly, Keeva, Gonzalez-Cordero, Anai
Publicado 2022

Retinal organoids: a window into human retinal development

por O'Hara-Wright, Michelle, Gonzalez-Cordero, Anai
Publicado 2020

Bioelectric Potential in Next-Generation Organoids: Electrical Stimulation to Enhance 3D Structures of the Central Nervous System

por O’Hara-Wright, Michelle, Mobini, Sahba, Gonzalez-Cordero, Anai
Publicado 2022

Comprehensive characterization of fetal and mature retinal cell identity to assess the fidelity of retinal organoids

por Kim, Hani Jieun, O’Hara-Wright, Michelle, Kim, Daniel, Loi, To Ha, Lim, Benjamin Y., Jamieson, Robyn V., Gonzalez-Cordero, Anai, Yang, Pengyi
Publicado 2023

Human stem cell-derived retinal epithelial cells activate complement via collectin 11 in response to stress

por Fanelli, Giorgia, Gonzalez-Cordero, Anai, Gardner, Peter J., Peng, Qi, Fernando, Milan, Kloc, Magdalena, Farrar, Conrad A., Naeem, Arifa, Garred, Peter, Ali, Robin R., Sacks, Steven H.
Publicado 2017

Human iPSC-Derived Retinal Organoids and Retinal Pigment Epithelium for Novel Intronic RPGR Variant Assessment for Therapy Suitability

por Chahine Karam, Fidelle, Loi, To Ha, Ma, Alan, Nash, Benjamin M., Grigg, John R., Parekh, Darshan, Riley, Lisa G., Farnsworth, Elizabeth, Bennetts, Bruce, Gonzalez-Cordero, Anai, Jamieson, Robyn V.
Publicado 2022

Evaluation for Retinal Therapy for RPE65 Variation Assessed in hiPSC Retinal Pigment Epithelial Cells

por Nash, Benjamin M., Loi, To Ha, Fernando, Milan, Sabri, Amin, Robinson, James, Cheng, Anson, Eamegdool, Steven S., Farnsworth, Elizabeth, Bennetts, Bruce, Grigg, John R., Chung, Seo-Kyung, Gonzalez-Cordero, Anai, Jamieson, Robyn V.
Publicado 2021

Multimodal analysis of ocular inflammation using the endotoxin-induced uveitis mouse model

por Chu, Colin J., Gardner, Peter J., Copland, David A., Liyanage, Sidath E., Gonzalez-Cordero, Anai, kleine Holthaus, Sophia-Martha, Luhmann, Ulrich F. O., Smith, Alexander J., Ali, Robin R., Dick, Andrew D.
Publicado 2016

Transplantation of Photoreceptor Precursors Isolated via a Cell Surface Biomarker Panel From Embryonic Stem Cell‐Derived Self‐Forming Retina

por Lakowski, Jorn, Gonzalez‐Cordero, Anai, West, Emma L., Han, Ya‐Ting, Welby, Emily, Naeem, Arifa, Blackford, Samuel J. I., Bainbridge, James W. B., Pearson, Rachael A., Ali, Robin R., Sowden, Jane C.
Publicado 2015

AAV-p40 Bioengineering Platform for Variant Selection Based on Transgene Expression

por Westhaus, Adrian, Cabanes-Creus, Marti, Jonker, Timo, Sallard, Erwan, Navarro, Renina Gale, Zhu, Erhua, Baltazar Torres, Grober, Lee, Scott, Wilmott, Patrick, Gonzalez-Cordero, Anai, Santilli, Giorgia, Thrasher, Adrian J., Alexander, Ian E., Lisowski, Leszek
Publicado 2022

Use of bioreactors for culturing human retinal organoids improves photoreceptor yields

por Ovando-Roche, Patrick, West, Emma L., Branch, Matthew J., Sampson, Robert D., Fernando, Milan, Munro, Peter, Georgiadis, Anastasios, Rizzi, Matteo, Kloc, Magdalena, Naeem, Arifa, Ribeiro, Joana, Smith, Alexander J., Gonzalez-Cordero, Anai, Ali, Robin R.
Publicado 2018

Differentiation of brain and retinal organoids from confluent cultures of pluripotent stem cells connected by nerve-like axonal projections of optic origin

por Fernando, Milan, Lee, Scott, Wark, Jesse R., Xiao, Di, Lim, Benjamin Y., O’Hara-Wright, Michelle, Kim, Hani J., Smith, Grady C., Wong, Ted, Teber, Erdahl T., Ali, Robin R., Yang, Pengyi, Graham, Mark E., Gonzalez-Cordero, Anai
Publicado 2022

Photoreceptor precursors derived from three-dimensional embryonic stem cell cultures integrate and mature within adult degenerate retina

por Gonzalez-Cordero, Anai, West, Emma L., Pearson, Rachael A., Duran, Yanai, Carvalho, Livia S., Chu, Colin J., Naeem, Arifa, Blackford, Samuel J. I., Georgiadis, Anastasios, Lakowski, Jorn, Hubank, Mike, Smith, Alexander J., Bainbridge, James W. B., Sowden, Jane C., Ali, Robin R.
Publicado 2013

Isolation and Comparative Transcriptome Analysis of Human Fetal and iPSC-Derived Cone Photoreceptor Cells

por Welby, Emily, Lakowski, Jorn, Di Foggia, Valentina, Budinger, Dimitri, Gonzalez-Cordero, Anai, Lun, Aaron T.L., Epstein, Michael, Patel, Aara, Cuevas, Elisa, Kruczek, Kamil, Naeem, Arifa, Minneci, Federico, Hubank, Mike, Jones, David T., Marioni, John C., Ali, Robin R., Sowden, Jane C.
Publicado 2017

Differentiation and Transplantation of Embryonic Stem Cell-Derived Cone Photoreceptors into a Mouse Model of End-Stage Retinal Degeneration

por Kruczek, Kamil, Gonzalez-Cordero, Anai, Goh, Debbie, Naeem, Arifa, Jonikas, Mindaugas, Blackford, Samuel J.I., Kloc, Magdalena, Duran, Yanai, Georgiadis, Anastasios, Sampson, Robert D., Maswood, Ryea N., Smith, Alexander J., Decembrini, Sarah, Arsenijevic, Yvan, Sowden, Jane C., Pearson, Rachael A., West, Emma L., Ali, Robin R.
Publicado 2017

High-Throughput In Vitro, Ex Vivo, and In Vivo Screen of Adeno-Associated Virus Vectors Based on Physical and Functional Transduction

por Westhaus, Adrian, Cabanes-Creus, Marti, Rybicki, Arkadiusz, Baltazar, Grober, Navarro, Renina Gale, Zhu, Erhua, Drouyer, Matthieu, Knight, Maddison, Albu, Razvan F., Ng, Boaz H., Kalajdzic, Predrag, Kwiatek, Magdalena, Hsu, Kenneth, Santilli, Giorgia, Gold, Wendy, Kramer, Belinda, Gonzalez-Cordero, Anai, Thrasher, Adrian J., Alexander, Ian E., Lisowski, Leszek
Publicado 2020

Antioxidant and lipid supplementation improve the development of photoreceptor outer segments in pluripotent stem cell-derived retinal organoids

por West, Emma L., Majumder, Paromita, Naeem, Arifa, Fernando, Milan, O'Hara-Wright, Michelle, Lanning, Emily, Kloc, Magdalena, Ribeiro, Joana, Ovando-Roche, Patrick, Shum, Ian O., Jumbu, Neeraj, Sampson, Robert, Hayes, Matt, Bainbridge, James W.B., Georgiadis, Anastasios, Smith, Alexander J., Gonzalez-Cordero, Anai, Ali, Robin R.
Publicado 2022

Restoration of visual function in advanced disease after transplantation of purified human pluripotent stem cell-derived cone photoreceptors

por Ribeiro, Joana, Procyk, Christopher A., West, Emma L., O’Hara-Wright, Michelle, Martins, Monica F., Khorasani, Majid Moshtagh, Hare, Aura, Basche, Mark, Fernando, Milan, Goh, Debbie, Jumbo, Neeraj, Rizzi, Matteo, Powell, Kate, Tariq, Menahil, Michaelides, Michel, Bainbridge, James W.B., Smith, Alexander J., Pearson, Rachael A., Gonzalez-Cordero, Anai, Ali, Robin R.
Publicado 2021

Recapitulation of Human Retinal Development from Human Pluripotent Stem Cells Generates Transplantable Populations of Cone Photoreceptors

por Gonzalez-Cordero, Anai, Kruczek, Kamil, Naeem, Arifa, Fernando, Milan, Kloc, Magdalena, Ribeiro, Joana, Goh, Debbie, Duran, Yanai, Blackford, Samuel J.I., Abelleira-Hervas, Laura, Sampson, Robert D., Shum, Ian O., Branch, Matthew J., Gardner, Peter J., Sowden, Jane C., Bainbridge, James W.B., Smith, Alexander J., West, Emma L., Pearson, Rachael A., Ali, Robin R.
Publicado 2017

Transplanted Donor- or Stem Cell-Derived Cone Photoreceptors Can Both Integrate and Undergo Material Transfer in an Environment-Dependent Manner

por Waldron, Paul V., Di Marco, Fabiana, Kruczek, Kamil, Ribeiro, Joana, Graca, Anna B., Hippert, Claire, Aghaizu, Nozie D., Kalargyrou, Aikaterini A., Barber, Amanda C., Grimaldi, Giulia, Duran, Yanai, Blackford, Samuel J.I., Kloc, Magdalena, Goh, Debbie, Zabala Aldunate, Eduardo, Sampson, Robert D., Bainbridge, James W.B., Smith, Alexander J., Gonzalez-Cordero, Anai, Sowden, Jane C., Ali, Robin R., Pearson, Rachael A.
Publicado 2018