Perturbation of cellular proteostasis networks identifies pathways that modulate precursor and intermediate but not mature levels of frataxin

por Nabhan, Joseph F., Gooch, Renea L., Piatnitski Chekler, Eugene L., Pierce, Betsy, Bulawa, Christine E.
Publicado 2015

Intrathecal delivery of frataxin mRNA encapsulated in lipid nanoparticles to dorsal root ganglia as a potential therapeutic for Friedreich’s ataxia

por Nabhan, Joseph F., Wood, Kristy M., Rao, Varada P., Morin, Jeffrey, Bhamidipaty, Surya, LaBranche, Timothy P., Gooch, Renea L., Bozal, Fazli, Bulawa, Christine E., Guild, Braydon C.
Publicado 2016

In vivo overexpression of frataxin causes toxicity mediated by iron-sulfur cluster deficiency

por Huichalaf, Claudia, Perfitt, Tyler L., Kuperman, Anna, Gooch, Renea, Kovi, Ramesh C., Brenneman, Karrie A., Chen, Xian, Hirenallur-Shanthappa, Dinesh, Ma, Tiffany, Assaf, Basel T., Pardo, Ingrid, Franks, Tania, Monarski, Laura, Cheng, Ting-Wen, Le, Kevin, Su, Chunyan, Somanathan, Suryanarayan, Whiteley, Laurence O., Bulawa, Christine, Pregel, Marko J., Martelli, Alain
Publicado 2022