The International Hundred Thousand Plus Cohort Consortium: integrating large-scale cohorts to address global scientific challenges

por Manolio, Teri A, Goodhand, Peter, Ginsburg, Geoffrey
Publicado 2020

Admission pattern and outcome in a UK weaning centre

por Goodhand, S, Stewart, K, McGee, L, Grey, N, Williams, A, Davidson, C, Hart, N
Publicado 2010

Anti-TNF Biologicals Enhance the Anti-Inflammatory Properties of IgG N-Glycome in Crohn’s Disease

por Hanić, Maja, Vučković, Frano, Deriš, Helena, Bewshea, Claire, Lin, Simeng, Goodhand, James R., Ahmad, Tariq, Trbojević-Akmačić, Irena, Kennedy, Nicholas A., Lauc, Gordan, Consortium, PANTS
Publicado 2023

855 PATIENT-LED REMOTE INTRACAPILLARY PHARMACOKINETIC SAMPLING (FINGERPRICKS): VALIDATION AND ACCEPTABILITY FOR HOME THERAPEUTIC DRUG MONITORING IN PATIENTS WITH IBD IN THE COVID-1...

por Chee, Desmond, Nice, Rachel, Hamilton, Benjamin, Jones, Edward, Hawkins, Sarah, Redstone, Clare, Cairnes, Vida, Pohl, Keith, Kennedy, Nick, Ahmad, Tariq, Goodhand, James, McDonald, Timothy J.
Publicado 2021

Understanding anti‐TNF treatment failure: does serum triiodothyronine‐to‐thyroxine (T3/T4) ratio predict therapeutic outcome to anti‐TNF therapies in biologic‐naïve patients with a...

por Lin, Simeng, Chanchlani, Neil, Carbery, Isabel, Janjua, Malik, Nice, Rachel, McDonald, Timothy J., Bewshea, Claire, Kennedy, Nicholas A., Ahmad, Tariq, Selinger, Christian P., Goodhand, James R.
Publicado 2022

Pretreatment Vitamin D Concentrations Do Not Predict Therapeutic Outcome to Anti-TNF Therapies in Biologic-Naïve Patients With Active Luminal Crohn’s Disease

por Chanchlani, Neil, Lin, Simeng, Smith, Rebecca, Roberts, Christopher, Nice, Rachel, McDonald, Timothy J, Hamilton, Benjamin, Bishara, Maria, Bewshea, Claire, Kennedy, Nicholas A, Goodhand, James R, Ahmad, Tariq
Publicado 2023

Genome-Wide Association Study of Microscopic Colitis in the UK Biobank Confirms Immune-Related Pathogenesis

por Green, Harry D, Beaumont, Robin N, Thomas, Amanda, Hamilton, Benjamin, Wood, Andrew R, Sharp, Seth, Jones, Samuel E, Tyrrell, Jessica, Walker, Gareth, Goodhand, James, Kennedy, Nicholas A, Ahmad, Tariq, Weedon, Michael N
Publicado 2019

Genetic evidence that higher central adiposity causes gastro-oesophageal reflux disease: a Mendelian randomization study

por Green, Harry D, Beaumont, Robin N, Wood, Andrew R, Hamilton, Benjamin, Jones, Samuel E, Goodhand, James R, Kennedy, Nicholas A, Ahmad, Tariq, Yaghootkar, Hanieh, Weedon, Michael N, Frayling, Timothy M, Tyrrell, Jessica
Publicado 2020

Root‐cause analyses of missed opportunities for the diagnosis of colorectal cancer in patients with inflammatory bowel disease

por Gordon, Claire, Chee, Desmond, Hamilton, Ben, Heerasing, Neel M., Hendy, Peter, Chanchlani, Neil, Lin, Simeng, Wesley, Emma, Daniels, Ian R., Silva, Nishanthi, Osborne, Melanie, Kennedy, Nicholas A., Goodhand, James R., Ahmad, Tariq
Publicado 2020

International federation of genomic medicine databases using GA4GH standards

por Thorogood, Adrian, Rehm, Heidi L., Goodhand, Peter, Page, Angela J.H., Joly, Yann, Baudis, Michael, Rambla, Jordi, Navarro, Arcadi, Nyronen, Tommi H., Linden, Mikael, Dove, Edward S., Fiume, Marc, Brudno, Michael, Cline, Melissa S., Birney, Ewan
Publicado 2021

Trust in genomic data sharing among members of the general public in the UK, USA, Canada and Australia

por Milne, Richard, Morley, Katherine I., Howard, Heidi, Niemiec, Emilia, Nicol, Dianne, Critchley, Christine, Prainsack, Barbara, Vears, Danya, Smith, James, Steed, Claire, Bevan, Paul, Atutornu, Jerome, Farley, Lauren, Goodhand, Peter, Thorogood, Adrian, Kleiderman, Erika, Middleton, Anna
Publicado 2019

Members of the public in the USA, UK, Canada and Australia expressing genetic exceptionalism say they are more willing to donate genomic data

por Middleton, Anna, Milne, Richard, Howard, Heidi, Niemiec, Emilia, Robarts, Lauren, Critchley, Christine, Nicol, Dianne, Prainsack, Barbara, Atutornu, Jerome, Vears, Danya F., Smith, James, Steed, Claire, Bevan, Paul, Scott, Erick R., Bobe, Jason, Goodhand, Peter, Kleiderman, Erika, Thorogood, Adrian, Morley, Katherine I.
Publicado 2019

Federated discovery and sharing of genomic data using Beacons

por Fiume, Marc, Cupak, Miroslav, Keenan, Stephen, Rambla, Jordi, de la Torre, Sabela, Dyke, Stephanie O. M., Brookes, Anthony J., Carey, Knox, Lloyd, David, Goodhand, Peter, Haeussler, Maximilian, Baudis, Michael, Stockinger, Heinz, Dolman, Lena, Lappalainen, Ilkka, Törnroos, Juha, Linden, Mikael, Spalding, J. Dylan, Ur-Rehman, Saif, Page, Angela, Flicek, Paul, Sherry, Stephen, Haussler, David, Varma, Susheel, Saunders, Gary, Scollen, Serena
Publicado 2019

Publisher Correction: Federated discovery and sharing of genomic data using Beacons

por Fiume, Marc, Cupak, Miroslav, Keenan, Stephen, Rambla, Jordi, de la Torre, Sabela, Dyke, Stephanie O. M., Brookes, Anthony J., Carey, Knox, Lloyd, David, Goodhand, Peter, Haeussler, Maximilian, Baudis, Michael, Stockinger, Heinz, Dolman, Lena, Lappalainen, Ilkka, Törnroos, Juha, Linden, Mikael, Spalding, J. Dylan, Ur-Rehman, Saif, Page, Angela, Flicek, Paul, Sherry, Stephen, Haussler, David, Varma, Susheel, Saunders, Gary, Scollen, Serena
Publicado 2019

Neutralising antibody potency against SARS-CoV-2 wild-type and omicron BA.1 and BA.4/5 variants in patients with inflammatory bowel disease treated with infliximab and vedolizumab...

por Liu, Zhigang, Le, Kaixing, Zhou, Xin, Alexander, James L, Lin, Simeng, Bewshea, Claire, Chanchlani, Neil, Nice, Rachel, McDonald, Timothy J, Lamb, Christopher A, Sebastian, Shaji, Kok, Klaartje, Lees, Charlie W, Hart, Ailsa L, Pollok, Richard C, Boyton, Rosemary J, Altmann, Daniel M, Pollock, Katrina M, Goodhand, James R, Kennedy, Nicholas A, Ahmad, Tariq, Powell, Nick
Publicado 2023

Adalimumab and Infliximab Impair SARS-CoV-2 Antibody Responses: Results from a Therapeutic Drug Monitoring Study in 11 422 Biologic-Treated Patients

por Chanchlani, Neil, Lin, Simeng, Chee, Desmond, Hamilton, Benjamin, Nice, Rachel, Arkir, Zehra, Bewshea, Claire, Cipriano, Bessie, Derikx, Lauranne A A P, Dunlop, Allan, Greathead, Louise, Griffiths, Rachel L, Ibraheim, Hajir, Kelleher, Peter, Kok, Klaartje B, Lees, Charlie W, MacDonald, Jonathan, Sebastian, Shaji, Smith, Philip J, McDonald, Timothy J, Irving, Peter M, Powell, Nick, Kennedy, Nicholas A, Goodhand, James R, Ahmad, Tariq
Publicado 2021

Su1485: COVID-19 VACCINE-INDUCED ANTIBODY RESPONSES ARE IMPAIRED IN IBD PATIENTS TREATED WITH INFLIXIMAB, USTEKINUMAB OR TOFACITINIB, BUT NOT THIOPURINES OR VEDOLIZUMAB

por Alexander, James L., Kennedy, Nick, Ibraheim, Hajir, Anandabaskaran, Sulak, Saifuddin, Aamir, Seoane, Rocio Castro, Liu, Zhigang, Nice, Rachel, Bewshea, Claire M., D'Mello, Andrea, Constable, Laura E., Jones, Gareth-Rhys, Balarajah, Sharmili, Fiorentino, Francesca, Sebastian, Shaji, Irving, Peter M., Hicks, Lucy C., Williams, Horace R., Kent, Alexandra J., Parkes, Miles, Kok, Klaartje, Patel, Kamal V, Altmann, Daniel, Boyton, Rosemary, Goodhand, James, Hart, Ailsa, Lees, Charlie W., Ahmad, Tariq, Powell, Nick
Publicado 2022

The gut microbiota and metabolome are associated with diminished COVID-19 vaccine-induced antibody responses in immunosuppressed inflammatory bowel disease patients

por Alexander, James L., Mullish, Benjamin H., Danckert, Nathan P., Liu, Zhigang, Olbei, Marton L., Saifuddin, Aamir, Torkizadeh, Melissa, Ibraheim, Hajir, Blanco, Jesús Miguéns, Roberts, Lauren A., Bewshea, Claire M., Nice, Rachel, Lin, Simeng, Prabhudev, Hemanth, Sands, Caroline, Horneffer-van der Sluis, Verena, Lewis, Matthew, Sebastian, Shaji, Lees, Charlie W., Teare, Julian P., Hart, Ailsa, Goodhand, James R., Kennedy, Nicholas A., Korcsmaros, Tamas, Marchesi, Julian R., Ahmad, Tariq, Powell, Nick
Publicado 2023

COVID-19 vaccine-induced antibody responses in immunosuppressed patients with inflammatory bowel disease (VIP): a multicentre, prospective, case-control study

por Alexander, James L, Kennedy, Nicholas A, Ibraheim, Hajir, Anandabaskaran, Sulak, Saifuddin, Aamir, Castro Seoane, Rocio, Liu, Zhigang, Nice, Rachel, Bewshea, Claire, D'Mello, Andrea, Constable, Laura, Jones, Gareth R, Balarajah, Sharmili, Fiorentino, Francesca, Sebastian, Shaji, Irving, Peter M, Hicks, Lucy C, Williams, Horace R T, Kent, Alexandra J, Linger, Rachel, Parkes, Miles, Kok, Klaartje, Patel, Kamal V, Teare, Julian P, Altmann, Daniel M, Boyton, Rosemary J, Goodhand, James R, Hart, Ailsa L, Lees, Charlie W, Ahmad, Tariq, Powell, Nick
Publicado 2022

Antibody decay, T cell immunity and breakthrough infections following two SARS-CoV-2 vaccine doses in inflammatory bowel disease patients treated with infliximab and vedolizumab

por Lin, Simeng, Kennedy, Nicholas A., Saifuddin, Aamir, Sandoval, Diana Muñoz, Reynolds, Catherine J., Seoane, Rocio Castro, Kottoor, Sherine H., Pieper, Franziska P., Lin, Kai-Min, Butler, David K., Chanchlani, Neil, Nice, Rachel, Chee, Desmond, Bewshea, Claire, Janjua, Malik, McDonald, Timothy J., Sebastian, Shaji, Alexander, James L., Constable, Laura, Lee, James C., Murray, Charles D., Hart, Ailsa L., Irving, Peter M., Jones, Gareth-Rhys, Kok, Klaartje B., Lamb, Christopher A., Lees, Charlie W., Altmann, Daniel M., Boyton, Rosemary J., Goodhand, James R., Powell, Nick, Ahmad, Tariq
Publicado 2022