Gremlin 1 — small protein, big impact: the multiorgan consequences of disrupted BMP antagonism(†)

por Gooding, Sarah, Leedham, Simon J
Publicado 2020

Tumor and microenvironmental mechanisms of resistance to immunomodulatory drugs in multiple myeloma

por Chen, Lucia Y., Gooding, Sarah
Publicado 2022

Set screw homogenization of murine ocular tissue, including the whole eye

por Gooding, Sarah W., Chrenek, Micah A., Ferdous, Salma, Nickerson, John M., Boatright, Jeffrey H.
Publicado 2018

Precision medicine for liver tumours with quantitative MRI and whole genome sequencing (Precision1 trial): study protocol for observational cohort study

por Welsh, Fenella K, Connell, John J, Kelly, Matt, Gooding, Sarah, Banerjee, Rajarshi, Rees, Myrddin
Publicado 2022

Pharmacological and genetic manipulations at the µ-opioid receptor reveal arrestin-3 engagement limits analgesic tolerance and does not exacerbate respiratory depression in mice

por He, Li, Gooding, Sarah W., Lewis, Elinor, Felth, Lindsey C., Gaur, Anirudh, Whistler, Jennifer L.
Publicado 2021

Multiple Myeloma Patient Tumors With High Levels of Cereblon Exon-10 Deletion Splice Variant Upregulate Clinically Targetable Pro-Inflammatory Cytokine Pathways

por Karagoz, Kubra, Stokes, Matthew, Ortiz-Estévez, María, Towfic, Fadi, Flynt, Erin, Gooding, Sarah, Pierceall, William, Thakurta, Anjan
Publicado 2022

Validation of clinical‐grade whole genome sequencing reproduces cytogenetic analysis and identifies mutational landscape in newly‐diagnosed multiple myeloma patients: A pilot study...

por Lomas, Oliver C., Gooding, Sarah, Cabes, Maite, Dreau, Helene, Wilson, Edward, Polzella, Paolo, Ramasamy, Karthik, Hamblin, Angela D.
Publicado 2021

P1362: DEVELOPMENT OF A NOVEL ONCOLYTIC VIRUS -THEO-310 - SPECIALISED FOR TARGETING THE BONE MARROW TUMOUR MICROENVIRONMENT OF MULTIPLE MYELOMA PATIENTS

por Bamford, Rebecca, Maleki-Toyserkani, Shayda, Taverner, Will, Freedman, Josh, Hayman, Matt, Saini, Manoj, Gooding, Sarah, Ramasamy, Karthik, Fisher, Kerry, Duffy, Margaret
Publicado 2023

Double Relapsed and/or Refractory Multiple Myeloma: Clinical Outcomes and Real World Healthcare Costs

por Gooding, Sarah, Lau, I-Jun, Sheikh, Mimi, Roberts, Pamela, Wong, Julia, Dickens, Emmy, Bullement, Ash, Elvidge, Jamie, Lee, Dawn, Ramasamy, Karthik
Publicado 2015

Impact of a T cell-based blood test for tuberculosis infection on clinical decision-making in routine practice

por Gooding, Sarah, Chowdhury, Oni, Hinks, Tim, Richeldi, Luca, Losi, Monica, Ewer, Katie, Millington, Kerry, Gunatheesan, Ruba, Cerri, Stefania, McNally, Jeremy, Lalvani, Ajit
Publicado 2007

Whole-genome analysis identifies novel drivers and high-risk double-hit events in relapsed/refractory myeloma

por Ansari-Pour, Naser, Samur, Mehmet, Flynt, Erin, Gooding, Sarah, Towfic, Fadi, Stong, Nicholas, Estevez, Maria Ortiz, Mavrommatis, Konstantinos, Walker, Brian, Morgan, Gareth, Munshi, Nikhil, Avet-Loiseau, Herve, Thakurta, Anjan
Publicado 2023

Multiple myeloma increases nerve growth factor and other pain-related markers through interactions with the bone microenvironment

por Olechnowicz, Sam W. Z., Weivoda, Megan M., Lwin, Seint T., Leung, Szi K., Gooding, Sarah, Nador, Guido, Javaid, Muhammed Kassim, Ramasamy, Karthik, Rao, Srinivasa R., Edwards, James R., Edwards, Claire M.
Publicado 2019

Loss of COP9 signalosome genes at 2q37 is associated with IMiD resistance in multiple myeloma

por Gooding, Sarah, Ansari-Pour, Naser, Kazeroun, Mohammad, Karagoz, Kubra, Polonskaia, Ann, Salazar, Mirian, Fitzsimons, Evie, Sirinukunwattana, Korsuk, Chavda, Selina, Ortiz Estevez, Maria, Towfic, Fadi, Flynt, Erin, Pierceall, William, Royston, Daniel, Yong, Kwee, Ramasamy, Karthik, Vyas, Paresh, Thakurta, Anjan
Publicado 2022

Immune response to COVID‐19 vaccination is attenuated by poor disease control and antimyeloma therapy with vaccine driven divergent T‐cell response

por Ramasamy, Karthik, Sadler, Ross, Jeans, Sally, Weeden, Paul, Varghese, Sherin, Turner, Alison, Larham, Jemma, Gray, Nathanael, Carty, Oluremi, Barrett, Joe, Bowcock, Stella, Oppermann, Udo, Cook, Gordon, Kyriakou, Chara, Drayson, Mark, Basu, Supratik, Moore, Sally, McDonald, Sarah, Gooding, Sarah, Javaid, Muhammad K.
Publicado 2022

Prospective Assessment of Tumour Burden and Bone Disease in Plasma Cell Dyscrasias Using DW-MRI and Exploratory Bone Biomarkers

por Agarwal, Gaurav, Nador, Guido, Varghese, Sherin, Getu, Hiwot, Palmer, Charlotte, Watson, Edmund, Pereira, Claudio, Sallemi, Germana, Partington, Karen, Patel, Neel, Soundarajan, Rajkumar, Mills, Rebecca, Brouwer, Richard, Maritati, Marina, Shah, Aarti, Peppercorn, Delia, Oppermann, Udo, Edwards, Claire M., Rodgers, Christopher T., Javaid, Muhammad Kassim, Gooding, Sarah, Ramasamy, Karthik
Publicado 2022

Transcriptomic profiling of the myeloma bone-lining niche reveals BMP signalling inhibition to improve bone disease

por Gooding, Sarah, Olechnowicz, Sam W. Z., Morris, Emma V., Armitage, Andrew E., Arezes, Joao, Frost, Joe, Repapi, Emmanouela, Edwards, James R., Ashley, Neil, Waugh, Craig, Gray, Nicola, Martinez-Hackert, Erik, Lim, Pei Jin, Pasricha, Sant-Rayn, Knowles, Helen, Mead, Adam J., Ramasamy, Karthik, Drakesmith, Hal, Edwards, Claire M.
Publicado 2019

Myeloma Genome Project Panel is a Comprehensive Targeted Genomics Panel for Molecular Profiling of Patients with Multiple Myeloma

por Sudha, Parvathi, Ahsan, Aarif, Ashby, Cody, Kausar, Tasneem, Khera, Akhil, Kazeroun, Mohammad H., Hsu, Chih-Chao, Wang, Lin, Fitzsimons, Evelyn, Salminen, Outi, Blaney, Patrick, Czader, Magdalena, Williams, Jonathan, Abu Zaid, Mohammad I., Ansari-Pour, Naser, Yong, Kwee L., van Rhee, Frits, Pierceall, William E., Morgan, Gareth J., Flynt, Erin, Gooding, Sarah, Abonour, Rafat, Ramasamy, Karthik, Thakurta, Anjan, Walker, Brian A.
Publicado 2022

Prolyl-tRNA synthetase as a novel therapeutic target in multiple myeloma

por Kurata, Keiji, James-Bott, Anna, Tye, Mark A., Yamamoto, Leona, Samur, Mehmet K., Tai, Yu-Tzu, Dunford, James, Johansson, Catrine, Senbabaoglu, Filiz, Philpott, Martin, Palmer, Charlotte, Ramasamy, Karthik, Gooding, Sarah, Smilova, Mihaela, Gaeta, Giorgia, Guo, Manman, Christianson, John C., Payne, N. Connor, Singh, Kritika, Karagoz, Kubra, Stokes, Matthew E., Ortiz, Maria, Hagner, Patrick, Thakurta, Anjan, Cribbs, Adam, Mazitschek, Ralph, Hideshima, Teru, Anderson, Kenneth C., Oppermann, Udo
Publicado 2023

Correction: Prolyl-tRNA synthetase as a novel therapeutic target in multiple myeloma

por Kurata, Keiji, James-Bott, Anna, Tye, Mark A., Yamamoto, Leona, Samur, Mehmet K., Tai, Yu-Tzu, Dunford, James, Johansson, Catrine, Senbabaoglu, Filiz, Philpott, Martin, Palmer, Charlotte, Ramasamy, Karthik, Gooding, Sarah, Smilova, Mihaela, Gaeta, Giorgia, Guo, Manman, Christianson, John C., Payne, N. Connor, Singh, Kritika, Karagoz, Kubra, Stokes, Matthew E., Ortiz, Maria, Hagner, Patrick, Thakurta, Anjan, Cribbs, Adam, Mazitschek, Ralph, Hideshima, Teru, Anderson, Kenneth C., Oppermann, Udo
Publicado 2023

Hepcidin is regulated by promoter-associated histone acetylation and HDAC3

por Pasricha, Sant-Rayn, Lim, Pei Jin, Duarte, Tiago L., Casu, Carla, Oosterhuis, Dorenda, Mleczko-Sanecka, Katarzyna, Suciu, Maria, Da Silva, Ana Rita, Al-Hourani, Kinda, Arezes, João, McHugh, Kirsty, Gooding, Sarah, Frost, Joe N., Wray, Katherine, Santos, Ana, Porto, Graça, Repapi, Emmanouela, Gray, Nicki, Draper, Simon J., Ashley, Neil, Soilleux, Elizabeth, Olinga, Peter, Muckenthaler, Martina U., Hughes, Jim R., Rivella, Stefano, Milne, Thomas A., Armitage, Andrew E., Drakesmith, Hal
Publicado 2017