Bacterial Biofilms Utilize an Underlying Extracellular DNA Matrix Structure That Can Be Targeted for Biofilm Resolution

por Goodman, Steven D., Bakaletz, Lauren O.
Publicado 2022

Targeting a bacterial DNABII protein with a chimeric peptide immunogen or humanised monoclonal antibody to prevent or treat recalcitrant biofilm-mediated infections

por Novotny, Laura A., Goodman, Steven D., Bakaletz, Lauren O.
Publicado 2020

ESKAPEE pathogens newly released from biofilm residence by a targeted monoclonal are sensitized to killing by traditional antibiotics

por Kurbatfinski, Nikola, Kramer, Cameron N., Goodman, Steven D., Bakaletz, Lauren O.
Publicado 2023

The conserved mosaic prophage protein paratox inhibits the natural competence regulator ComR in Streptococcus

por Mashburn-Warren, Lauren, Goodman, Steven D., Federle, Michael J., Prehna, Gerd
Publicado 2018

Monoclonal antibodies against DNA-binding tips of DNABII proteins disrupt biofilms in vitro and induce bacterial clearance in vivo

por Novotny, Laura A., Jurcisek, Joseph A., Goodman, Steven D., Bakaletz, Lauren O.
Publicado 2016

Monoclonal antibodies that target extracellular DNABII proteins or the type IV pilus of nontypeable Haemophilus influenzae (NTHI) worked additively to disrupt 2-genera biofilms

por Jurcisek, Joseph A., Hofer, Llwyatt K., Goodman, Steven D., Bakaletz, Lauren O.
Publicado 2022

The DNABII family of proteins is comprised of the only nucleoid associated proteins required for nontypeable Haemophilus influenzae biofilm structure

por Devaraj, Aishwarya, Buzzo, John, Rocco, Christopher J., Bakaletz, Lauren O., Goodman, Steven D.
Publicado 2017

Lactobacillus reuteri in Its Biofilm State Improves Protection from Experimental Necrotizing Enterocolitis

por Al-Hadidi, Ameer, Navarro, Jason, Goodman, Steven D., Bailey, Michael T., Besner, Gail E.
Publicado 2021

The dental plaque biofilm matrix

por Jakubovics, Nicholas S., Goodman, Steven D., Mashburn-Warren, Lauren, Stafford, Graham P., Cieplik, Fabian
Publicado 2021

A Biochemical Analysis of the Interaction of Porphyromonas gingivalis HU PG0121 Protein with DNA

por Tjokro, Natalia O., Rocco, Christopher J., Priyadarshini, Richa, Davey, Mary E., Goodman, Steven D.
Publicado 2014

Enhanced Probiotic Potential of Lactobacillus reuteri When Delivered as a Biofilm on Dextranomer Microspheres That Contain Beneficial Cargo

por Navarro, Jason B., Mashburn-Warren, Lauren, Bakaletz, Lauren O., Bailey, Michael T., Goodman, Steven D.
Publicado 2017

Immunization with a Biofilm-Disrupting Nontypeable Haemophilus influenzae Vaccine Antigen Did Not Alter the Gut Microbiome in Chinchillas, Unlike Oral Delivery of a Broad-Spectrum...

por Bailey, Michael T., Lauber, Christian L., Novotny, Laura A., Goodman, Steven D., Bakaletz, Lauren O.
Publicado 2020

Next-Generation Probiotic Therapy to Protect the Intestines From Injury

por Ragan, Mecklin V., Wala, Samantha J., Goodman, Steven D., Bailey, Michael T., Besner, Gail E.
Publicado 2022

Structural Stability of Burkholderia cenocepacia Biofilms Is Reliant on eDNA Structure and Presence of a Bacterial Nucleic Acid Binding Protein

por Novotny, Laura A., Amer, Amal O., Brockson, M. Elizabeth, Goodman, Steven D., Bakaletz, Lauren O.
Publicado 2013

A Biochemical Characterization of the DNA Binding Activity of the Response Regulator VicR from Streptococcus mutans

por Ayala, Eduardo, Downey, Jennifer S., Mashburn-Warren, Lauren, Senadheera, Dilani B., Cvitkovitch, Dennis G., Goodman, Steven D.
Publicado 2014

Nontypeable Haemophilus influenzae released from biofilm residence by monoclonal antibody directed against a biofilm matrix component display a vulnerable phenotype

por Wilbanks, Kathryn Q., Mokrzan, Elaine M., Kesler, Theresa M., Kurbatfinski, Nikola, Goodman, Steven D., Bakaletz, Lauren O.
Publicado 2023

Escherichia coli HU protein has a role in the repair of abasic sites in DNA

por Kow, Yoke W., Imhoff, Barry, Weiss, Bernard, Hung, David C. I., Hindoyan, Antreas A., Story, Randall M., Goodman, Steven D.
Publicado 2007

Escherichia coli HU protein has a role in the repair of abasic sites in DNA

por Kow, Yoke W., Imhoff, Barry, Weiss, Bernard, Hung, David C. I., Hindoyan, Antreas A., Story, Randall M., Goodman, Steven D.
Publicado 2009

Nontypeable Haemophilus influenzae newly released (NRel) from biofilms by antibody-mediated dispersal versus antibody-mediated disruption are phenotypically distinct

por Mokrzan, Elaine M., Ahearn, Christian P., Buzzo, John R., Novotny, Laura A., Zhang, Yan, Goodman, Steven D., Bakaletz, Lauren O.
Publicado 2020

HMGA2 exhibits dRP/AP site cleavage activity and protects cancer cells from DNA-damage-induced cytotoxicity during chemotherapy

por Summer, Heike, Li, Ou, Bao, Qiuye, Zhan, Lihong, Peter, Sabrina, Sathiyanathan, Padmapriya, Henderson, Dana, Klonisch, Thomas, Goodman, Steven D., Dröge, Peter
Publicado 2009