COVID‐19, varying genetic resistance to viral disease and immune tolerance checkpoints

por Goodnow, Christopher C
Publicado 2020

Organ-Specific Autoimmune Disease: A Deficiency of Tolerogenic Stimulation

por Lesage, Sylvie, Goodnow, Christopher C.
Publicado 2001

Gene Dose–Dependent Maturation and Receptor Editing of B Cells Expressing Immunoglobulin (Ig)g1 or Igm/Igg1 Tail Antigen Receptors

por Pogue, Sarah L., Goodnow, Christopher C.
Publicado 2000

Abortive Proliferation of Rare T Cells Induced by Direct or Indirect Antigen Presentation by Rare B Cells In Vivo

por Townsend, Sarah E., Goodnow, Christopher C.
Publicado 1998

Self-reactive B Cells Are Not Eliminated or Inactivated by Autoantigen Expressed on Thyroid Epithelial Cells

por Akkaraju, Srinivas, Canaan, Karen, Goodnow, Christopher C.
Publicado 1997

Helios marks strongly autoreactive CD4(+) T cells in two major waves of thymic deletion distinguished by induction of PD-1 or NF-κB

por Daley, Stephen R., Hu, Daniel Y., Goodnow, Christopher C.
Publicado 2013

Analysis of an Ethylnitrosourea-generated Mouse Mutation Defines a Cell Intrinsic Role of Nuclear Factor κB2 in Regulating Circulating B Cell Numbers

por Miosge, Lisa A., Blasioli, Julie, Blery, Mathieu, Goodnow, Christopher C.
Publicado 2002

Clonal redemption of autoantibodies by somatic hypermutation away from self-reactivity during human immunization

por Reed, Joanne H., Jackson, Jennifer, Christ, Daniel, Goodnow, Christopher C.
Publicado 2016

Differential Requirement for the CD45 Splicing Regulator hnRNPLL for Accumulation of NKT and Conventional T Cells

por Yabas, Mehmet, Godfrey, Dale I., Goodnow, Christopher C., Hoyne, Gerard F.
Publicado 2011

Consequences of the recurrent MYD88(L265P) somatic mutation for B cell tolerance

por Wang, James Q., Jeelall, Yogesh S., Beutler, Bruce, Horikawa, Keisuke, Goodnow, Christopher C.
Publicado 2014

DeepSNVMiner: a sequence analysis tool to detect emergent, rare mutations in subsets of cell populations

por Andrews, T. Daniel, Jeelall, Yogesh, Talaulikar, Dipti, Goodnow, Christopher C., Field, Matthew A.
Publicado 2016

Essential role of membrane cholesterol in accelerated BCR internalization and uncoupling from NF-κB in B cell clonal anergy

por Bléry, Mathieu, Tze, Lina, Miosge, Lisa A., Jun, Jesse E., Goodnow, Christopher C.
Publicado 2006

CD19-Regulated Signaling Thresholds Control Peripheral Tolerance and Autoantibody Production in B Lymphocytes

por Inaoki, Makoto, Sato, Shinichi, Weintraub, Bennett C., Goodnow, Christopher C., Tedder, Thomas F.
Publicado 1997

Failure to Censor Forbidden Clones of CD4 T Cells in Autoimmune Diabetes

por Lesage, Sylvie, Hartley, Suzanne B., Akkaraju, Srinivas, Wilson, Judith, Townsend, Michelle, Goodnow, Christopher C.
Publicado 2002

Spontaneous Follicular Exclusion of SHP1-deficient B Cells Is Conditional on the Presence of Competitor Wild-type B Cells

por Schmidt, Kerstin N., Hsu, Christopher W., Griffin, Courtney T., Goodnow, Christopher C., Cyster, Jason G.
Publicado 1998

Repression of B7.2 on Self-reactive B Cells Is Essential to Prevent Proliferation and Allow Fas-mediated Deletion by CD4(+) T Cells

por Rathmell, Jeffrey C., Fournier, Sylvie, Weintraub, Bennett C., Allison, James P., Goodnow, Christopher C.
Publicado 1998

Murine LRBA deficiency causes CTLA-4 deficiency in Tregs without progression to immune dysregulation

por Burnett, Deborah L, Parish, Ian A, Masle-Farquhar, Etienne, Brink, Robert, Goodnow, Christopher C
Publicado 2017

Loss-of-function of Fbxo10, encoding a post-translational regulator of BCL2 in lymphomas, has no discernible effect on BCL2 or B lymphocyte accumulation in mice

por Masle-Farquhar, Etienne, Russell, Amanda, Li, Yangguang, Zhu, Fen, Rui, Lixin, Brink, Robert, Goodnow, Christopher C.
Publicado 2021

Enhancement and suppression of signaling by the conserved tail of IgG memory–type B cell antigen receptors

por Horikawa, Keisuke, Martin, Stephen W., Pogue, Sarah L., Silver, Karlee, Peng, Kaiman, Takatsu, Kiyoshi, Goodnow, Christopher C.
Publicado 2007

Calling differentially methylated regions from whole genome bisulphite sequencing with DMRcate

por Peters, Timothy J, Buckley, Michael J, Chen, Yunshun, Smyth, Gordon K, Goodnow, Christopher C, Clark, Susan J
Publicado 2021