Generation and characterization of new monoclonal antibodies targeting the PHF1 and AT8 epitopes on human tau

por Strang, Kevin H., Goodwin, Marshall S., Riffe, Cara, Moore, Brenda D., Chakrabarty, Paramita, Levites, Yona, Golde, Todd E., Giasson, Benoit I.
Publicado 2017

Intracerebral but Not Peripheral Infection of Live Porphyromonas gingivalis Exacerbates Alzheimer’s Disease Like Amyloid Pathology in APP-TgCRND8 Mice

por Aravindraja, Chairmandurai, Sakthivel, Ravi, Liu, Xuefei, Goodwin, Marshall, Veena, Patnam, Godovikova, Valentina, Fenno, J. Christopher, Levites, Yona, Golde, Todd E., Kesavalu, Lakshmyya
Publicado 2022

Anti-tau scFvs Targeted to the Cytoplasm or Secretory Pathway Variably Modify Pathology and Neurodegenerative Phenotypes

por Goodwin, Marshall S., Sinyavskaya, Olga, Burg, Franklin, O’Neal, Veronica, Ceballos-Diaz, Carolina, Cruz, Pedro E., Lewis, Jada, Giasson, Benoit I., Davies, Peter, Golde, Todd E., Levites, Yona
Publicado 2021

Optical pulse labeling studies reveal exogenous seeding slows α-synuclein clearance

por Croft, Cara L., Paterno, Giavanna, Vause, Ava R., Rowe, Lyla A., Ryu, Daniel H., Goodwin, Marshall S., Moran, Corey A., Cruz, Pedro E., Giasson, Benoit I., Golde, Todd E.
Publicado 2022

Unique α-synuclein pathology within the amygdala in Lewy body dementia: implications for disease initiation and progression

por Sorrentino, Zachary A., Goodwin, Marshall S., Riffe, Cara J., Dhillon, Jess-Karan S., Xia, Yuxing, Gorion, Kimberly-Marie, Vijayaraghavan, Niran, McFarland, Karen N., Golbe, Lawrence I., Yachnis, Anthony T., Giasson, Benoit I.
Publicado 2019

A C1qTNF3 collagen domain fusion chaperones diverse secreted proteins and anti-Aβ scFvs: Applications for gene therapies

por Moore, Brenda D., Ran, Yong, Goodwin, Marshall S., Komatineni, Kavitha, McFarland, Karen N., Dillon, Kristy, Charles, Caleb, Ryu, Danny, Liu, Xuefei, Prokop, Stefan, Giasson, Benoit I., Golde, Todd E., Levites, Yona
Publicado 2023

Photodynamic studies reveal rapid formation and appreciable turnover of tau inclusions

por Croft, Cara L., Goodwin, Marshall S., Ryu, Daniel H., Lessard, Christian B., Tejeda, Giancarlo, Marrero, Marc, Vause, Ava R., Paterno, Giavanna, Cruz, Pedro E., Lewis, Jada, Giasson, Benoit I., Golde, Todd E.
Publicado 2021

LRP1 is a neuronal receptor for α-synuclein uptake and spread

por Chen, Kai, Martens, Yuka A., Meneses, Axel, Ryu, Daniel H., Lu, Wenyan, Raulin, Ana Caroline, Li, Fuyao, Zhao, Jing, Chen, Yixing, Jin, Yunjung, Linares, Cynthia, Goodwin, Marshall, Li, Yonghe, Liu, Chia-Chen, Kanekiyo, Takahisa, Holtzman, David M., Golde, Todd E., Bu, Guojun, Zhao, Na
Publicado 2022

Utilizing minimally purified secreted rAAV for rapid and cost-effective manipulation of gene expression in the CNS

por Goodwin, Marshall S., Croft, Cara L., Futch, Hunter S., Ryu, Daniel, Ceballos-Diaz, Carolina, Liu, Xuefei, Paterno, Giavanna, Mejia, Catalina, Deng, Doris, Menezes, Kimberly, Londono, Laura, Arjona, Kefren, Parianos, Mary, Truong, Van, Rostonics, Eva, Hernandez, Amanda, Boye, Sanford L., Boye, Shannon E., Levites, Yona, Cruz, Pedro E., Golde, Todd E.
Publicado 2020

An anti-CRF antibody suppresses the HPA axis and reverses stress-induced phenotypes

por Futch, Hunter S., McFarland, Karen N., Moore, Brenda D., Kuhn, M. Zino, Giasson, Benoit I., Ladd, Thomas B., Scott, Karen A., Shapiro, Melanie R., Nosacka, Rachel L., Goodwin, Marshall S., Ran, Yong, Cruz, Pedro E., Ryu, Daniel H., Croft, Cara L., Levites, Yona, Janus, Christopher, Chakrabarty, Paramita, Judge, Andrew R., Brusko, Todd M., de Kloet, Annette D., Krause, Eric G., Golde, Todd E.
Publicado 2019