Integrated Chemometrics and Statistics to Drive Successful Proteomics Biomarker Discovery

por Suppers, Anouk, van Gool, Alain J., Wessels, Hans J. C. T.
Publicado 2018

The funhouse mirror: the I in personalised healthcare

por Vegter, Mira W., Zwart, Hub A. E., van Gool, Alain J.
Publicado 2021

Network signatures link hepatic effects of anti-diabetic interventions with systemic disease parameters

por Kelder, Thomas, Verschuren, Lars, van Ommen, Ben, van Gool, Alain J, Radonjic, Marijana
Publicado 2014

Inflammatory cytokine oncostatin M induces endothelial activation in macro- and microvascular endothelial cells and in APOE*3Leiden.CETP mice

por van Keulen, Danielle, Pouwer, Marianne G., Pasterkamp, Gerard, van Gool, Alain J., Sollewijn Gelpke, Maarten D., Princen, Hans M. G., Tempel, Dennie
Publicado 2018

Inflammation biomarker discovery in Parkinson’s disease and atypical parkinsonisms

por Santaella, Anna, Kuiperij, H. Bea, van Rumund, Anouke, Esselink, Rianne A. J., van Gool, Alain J., Bloem, Bastiaan R., Verbeek, Marcel M.
Publicado 2020

Cerebrospinal fluid monocyte chemoattractant protein 1 correlates with progression of Parkinson’s disease

por Santaella, Anna, Kuiperij, H. Bea, van Rumund, Anouke, Esselink, Rianne A. J., van Gool, Alain J., Bloem, Bastiaan R., Verbeek, Marcel M.
Publicado 2020

Metabolomic predictors of phenotypic traits can replace and complement measured clinical variables in population-scale expression profiling studies

por Niehues, Anna, Bizzarri, Daniele, Reinders, Marcel J.T., Slagboom, P. Eline, van Gool, Alain J., van den Akker, Erik B., ’t Hoen, Peter A.C.
Publicado 2022

An integrated framework of personalized medicine: from individual genomes to participatory health care

por Evers, Andrea W.M., Rovers, Maroeska M., Kremer, Jan A.M., Veltman, Joris A., Schalken, Jack A., Bloem, Bas R., van Gool, Alain J.
Publicado 2012

The GlycoPaSER Prototype as a Real-Time N-Glycopeptide Identification Tool Based on the PaSER Parallel Computing Platform

por Armony, Gad, Brehmer, Sven, Srikumar, Tharan, Pfennig, Lennard, Zijlstra, Fokje, Trede, Dennis, Kruppa, Gary, Lefeber, Dirk J., van Gool, Alain J., Wessels, Hans J. C. T.
Publicado 2023

Qualitative evaluation of coronary atherosclerosis in a large cohort of young and middle-aged Dutch tissue donors implies that coronary thrombo-embolic manifestations are stochasti...

por Lindeman, Jan H., Hulsbos, Luuk, van den Bogaerdt, Antoon J., Geerts, Marlieke, van Gool, Alain J., Hamming, Jaap F., van Dijk, Rogier A., Schaapherder, Alexander F.
Publicado 2018

Proteomic profiling of striatal tissue of a rat model of Parkinson's disease after implantation of collagen‐encapsulated human umbilical cord mesenchymal stem cells

por Santaella, Anna, Wessels, Hans J.C.T., Kulkarni, Purva, Gloerich, Jolein, Kuiperij, Bea, Bloem, Bastiaan R., van Gool, Alain J., Cabré, Silvia, Alamilla, Verónica, Verbeek, Marcel M.
Publicado 2020

Ten quick tips for building FAIR workflows

por de Visser, Casper, Johansson, Lennart F., Kulkarni, Purva, Mei, Hailiang, Neerincx, Pieter, Joeri van der Velde, K., Horvatovich, Péter, van Gool, Alain J., Swertz, Morris A., Hoen, Peter A. C. ‘t, Niehues, Anna
Publicado 2023

Common Variants Associated With OSMR Expression Contribute to Carotid Plaque Vulnerability, but Not to Cardiovascular Disease in Humans

por van Keulen, Danielle, van Koeverden, Ian D., Boltjes, Arjan, Princen, Hans M. G., van Gool, Alain J., de Borst, Gert J., Asselbergs, Folkert W., Tempel, Dennie, Pasterkamp, Gerard, van der Laan, Sander W.
Publicado 2021

Analysis of 953 Human Proteins from a Mitochondrial HEK293 Fraction by Complexome Profiling

por Wessels, Hans J. C. T., Vogel, Rutger O., Lightowlers, Robert N., Spelbrink, Johannes N., Rodenburg, Richard J., van den Heuvel, Lambert P., van Gool, Alain J., Gloerich, Jolein, Smeitink, Jan A. M., Nijtmans, Leo G.
Publicado 2013

Fasting Proinsulin Independently Predicts Incident Type 2 Diabetes in the General Population

por Sokooti, Sara, Dam, Wendy A., Szili-Torok, Tamas, Gloerich, Jolein, van Gool, Alain J., Post, Adrian, de Borst, Martin H., Gansevoort, Ron T., Heerspink, Hiddo J. L., Dullaart, Robin P. F., Bakker, Stephan J. L.
Publicado 2022

Plasma C-Peptide and Risk of Developing Type 2 Diabetes in the General Population

por Sokooti, Sara, Kieneker, Lyanne M., de Borst, Martin H., Muller Kobold, Anneke, Kootstra-Ros, Jenny E., Gloerich, Jolein, van Gool, Alain J., Heerspink, Hiddo J. Lambers, T Gansevoort, Ron, Dullaart, Robin P.F., Bakker, Stephan J. L.
Publicado 2020

Circulating FGF21 Concentration, Fasting Plasma Glucose, and the Risk of Type 2 Diabetes: Results From the PREVEND Study

por Post, Adrian, Dam, Wendy A, Sokooti, Sara, Groothof, Dion, Gloerich, Jolein, van Gool, Alain J, Kremer, Daan, Gansevoort, Ron T, van den Born, Jacob, Kema, Ido P, Franssen, Casper F M, Dullaart, Robin P F, Bakker, Stephan J L
Publicado 2022

Metabolomics-Based Screening of Inborn Errors of Metabolism: Enhancing Clinical Application with a Robust Computational Pipeline

por Hoegen, Brechtje, Zammit, Alan, Gerritsen, Albert, Engelke, Udo F. H., Castelein, Steven, van de Vorst, Maartje, Kluijtmans, Leo A. J., Huigen, Marleen C. D. G., Wevers, Ron A., van Gool, Alain J., Gilissen, Christian, Coene, Karlien L. M., Kulkarni, Purva
Publicado 2021

Integrated Human Evaluation of the Lysophosphatidic Acid Pathway as a Novel Therapeutic Target in Atherosclerosis

por Aldi, Silvia, Matic, Ljubica Perisic, Hamm, Gregory, van Keulen, Daniëlle, Tempel, Dennie, Holmstrøm, Kim, Szwajda, Agnieszka, Nielsen, Boye Schnack, Emilsson, Valur, Ait-Belkacem, Rima, Lengquist, Mariette, Paulsson-Berne, Gabrielle, Eriksson, Per, Lindeman, Jan H.N., Gool, Alain J., Stauber, Jonathan, Hedin, Ulf, Hurt-Camejo, Eva
Publicado 2018

Oncostatin M reduces atherosclerosis development in APOE*3Leiden.CETP mice and is associated with increased survival probability in humans

por van Keulen, Danielle, Pouwer, Marianne G., Emilsson, Valur, Matic, Ljubica Perisic, Pieterman, Elsbet J., Hedin, Ulf, Gudnason, Vilmundur, Jennings, Lori L., Holmstrøm, Kim, Nielsen, Boye Schnack, Pasterkamp, Gerard, Lindeman, Jan H. N., van Gool, Alain J., Sollewijn Gelpke, Maarten D., Princen, Hans M. G., Tempel, Dennie
Publicado 2019