CNX-012-570, a direct AMPK activator provides strong glycemic and lipid control along with significant reduction in body weight; studies from both diet-induced obese mice and db/db...

por Anil, Tharappel M, Harish, Chandrashekaran, Lakshmi, Mudigere N, Harsha, KrishnaReddy, Onkaramurthy, Mallappa, Sathish Kumar, Venkatesh, Shree, Nitya, Geetha, Venkatachalaiah, Balamurali, Gundalmandikal V, Gopala, Aralakuppe S, Madhusudhan Reddy, Bobbili, Govind, Madabosse K, Anup, Mammen O, Moolemath, Yoganand, Venkataranganna, Marikunte V, Jagannath, Madanahalli R, Somesh, Baggavalli P
Publicado 2014

A novel 11β-hydroxysteroid dehydrogenase type1 inhibitor CNX-010-49 improves hyperglycemia, lipid profile and reduces body weight in diet induced obese C57B6/J mice with a potentia...

por Anil, Tharappel M, Dandu, Anilkumar, Harsha, KrishnaReddy, Singh, Jaideep, Shree, Nitya, Kumar, Venkatesh Satish, Lakshmi, Mudigere N, Sunil, Venkategowda, Harish, Chandrashekaran, Balamurali, Gundalmandikal V, Naveen Kumar, Baisani S, Gopala, Aralakuppe S, Pratibha, Shivakumar, Sadasivuni, ManojKumar, Anup, Mammen O, Moolemath, Yoganand, Venkataranganna, Marikunte V, Jagannath, Madanahalli R, Somesh, Baggavalli P
Publicado 2014

CNX-013-B2, a unique pan tissue acting rexinoid, modulates several nuclear receptors and controls multiple risk factors of the metabolic syndrome without risk of hypertriglyceridem...

por Sadasivuni, Manoj Kumar, Reddy, Bobbili Madhusudhan, Singh, Jaideep, Anup, Mammen O, Sunil, Venkategowda, Lakshmi, Mudigere N, Yogeshwari, Sivakumaran, Chacko, Suni K, Pooja, Talanki Lokesh, Dandu, Anilkumar, Harish, Chandrashekaran, Gopala, Aralakuppe S, Pratibha, Shivakumar, Naveenkumar, Baisani S, Pallavi, Puttrevana M, Verma, Mahesh Kumar, Moolemath, Yoganand, Somesh, Baggavalli P, Venkataranganna, Marikunte V, Jagannath, Madanahalli R
Publicado 2014