Histone deacetylase inhibitors enhance oncolytic herpes simplex virus therapy for malignant meningioma

por Kawamura, Yoichiro, Hua, Lingyang, Gurtner, Alessandra, Wong, Ego, Kiyokawa, Juri, Shah, Nadia, Gorham, Joshua, Wakimoto, Hiroko, Rabkin, Samuel D., Martuza, Robert L., Wakimoto, Hiroaki
Publicado 2022

ViroFind: A novel target-enrichment deep-sequencing platform reveals a complex JC virus population in the brain of PML patients

por Chalkias, Spyros, Gorham, Joshua M., Mazaika, Erica, Parfenov, Michael, Dang, Xin, DePalma, Steve, McKean, David, Seidman, Christine E., Seidman, Jonathan G., Koralnik, Igor J.
Publicado 2018

Myc targeted CDK18 promotes ATR and homologous recombination to mediate PARP inhibitor resistance in glioblastoma

por Ning, Jian-Fang, Stanciu, Monica, Humphrey, Melissa R., Gorham, Joshua, Wakimoto, Hiroko, Nishihara, Reiko, Lees, Jacqueline, Zou, Lee, Martuza, Robert L., Wakimoto, Hiroaki, Rabkin, Samuel D.
Publicado 2019

Cardiomyocyte Proliferative Capacity Is Restricted in Mice With Lmna Mutation

por Onoue, Kenji, Wakimoto, Hiroko, Jiang, Jiangming, Parfenov, Michael, DePalma, Steven, Conner, David, Gorham, Joshua, McKean, David, Seidman, Jonathan G., Seidman, Christine E., Saito, Yoshihiko
Publicado 2021

Cardiovascular homeostasis dependence on MICU2, a regulatory subunit of the mitochondrial calcium uniporter

por Bick, Alexander G., Wakimoto, Hiroko, Kamer, Kimberli J., Sancak, Yasemin, Goldberger, Olga, Axelsson, Anna, DeLaughter, Daniel M., Gorham, Joshua M., Mootha, Vamsi K., Seidman, J. G., Seidman, Christine E.
Publicado 2017

Joint analysis of left ventricular expression and circulating plasma levels of Omentin after myocardial ischemia

por Saddic, Louis A., Nicoloro, Sarah M., Gupta, Olga T., Czech, Michael P., Gorham, Joshua, Shernan, Stanton K., Seidman, Christine E., Seidman, Jon G., Aranki, Sary F., Body, Simon C., Fitzgibbons, Timothy P., Muehlschlegel, Jochen D.
Publicado 2017

The extracellular matrix proteoglycan lumican improves survival and counteracts cardiac dilatation and failure in mice subjected to pressure overload

por Mohammadzadeh, Naiyereh, Lunde, Ida G., Andenæs, Kine, Strand, Mari E., Aronsen, Jan Magnus, Skrbic, Biljana, Marstein, Henriette S., Bandlien, Caroline, Nygård, Ståle, Gorham, Joshua, Sjaastad, Ivar, Chakravarti, Shukti, Christensen, Geir, Engebretsen, Kristin V. T., Tønnessen, Theis
Publicado 2019

LAMP2 Cardiomyopathy: Consequences of Impaired Autophagy in the Heart

por Alcalai, Ronny, Arad, Michael, Wakimoto, Hiroko, Yadin, Dor, Gorham, Joshua, Wang, Libin, Burns, Elia, Maron, Barry J., Roberts, William C., Konno, Tetsuo, Conner, David A., Perez‐Atayde, Antonio R., Seidman, Jon G., Seidman, Christine E.
Publicado 2021

Pathogenesis of Cardiomyopathy Caused by Variants in ALPK3, an Essential Pseudokinase in the Cardiomyocyte Nucleus and Sarcomere

por Agarwal, Radhika, Wakimoto, Hiroko, Paulo, Joao A., Zhang, Qi, Reichart, Daniel, Toepfer, Christopher, Sharma, Arun, Tai, Angela C., Lun, Mingyue, Gorham, Joshua, DePalma, Steven R., Gygi, Steven P., Seidman, J.G., Seidman, Christine E.
Publicado 2022

Plakophilin-2 truncating variants impair cardiac contractility by disrupting sarcomere stability and organization

por Zhang, Kehan, Cloonan, Paige E., Sundaram, Subramanian, Liu, Feng, Das, Shoshana L., Ewoldt, Jourdan K., Bays, Jennifer L., Tomp, Samuel, Toepfer, Christopher N., Marsiglia, Júlia D. C., Gorham, Joshua, Reichart, Daniel, Eyckmans, Jeroen, Seidman, Jonathan G., Seidman, Christine E., Chen, Christopher S.
Publicado 2021

Cardiomyocyte infection by Trypanosoma cruzi promotes innate immune response and glycolysis activation

por Venturini, Gabriela, Alvim, Juliana M., Padilha, Kallyandra, Toepfer, Christopher N., Gorham, Joshua M., Wasson, Lauren K., Biagi, Diogo, Schenkman, Sergio, Carvalho, Valdemir M., Salgueiro, Jessica S., Cardozo, Karina H. M., Krieger, Jose E., Pereira, Alexandre C., Seidman, Jonathan G., Seidman, Christine E.
Publicado 2023

Small-Molecule Screen Identifies De Novo Nucleotide Synthesis as a Vulnerability of Cells Lacking SIRT3

por Gonzalez Herrera, Karina N., Zaganjor, Elma, Ishikawa, Yoshinori, Spinelli, Jessica B., Yoon, Haejin, Lin, Jia-Ren, Satterstrom, F. Kyle, Ringel, Alison, Mulei, Stacy, Souza, Amanda, Gorham, Joshua M., Benson, Craig C., Seidman, Jonathan G., Sorger, Peter K., Clish, Clary B., Haigis, Marcia C.
Publicado 2018

Efficient in vivo genome editing prevents hypertrophic cardiomyopathy in mice

por Reichart, Daniel, Newby, Gregory A., Wakimoto, Hiroko, Lun, Mingyue, Gorham, Joshua M., Curran, Justin J., Raguram, Aditya, DeLaughter, Daniel M., Conner, David A., Marsiglia, Júlia D. C., Kohli, Sajeev, Chmatal, Lukas, Page, David C., Zabaleta, Nerea, Vandenberghe, Luk, Liu, David R., Seidman, Jonathan G., Seidman, Christine
Publicado 2023

Dissecting spatio-temporal protein networks driving human heart development and related disorders

por Lage, Kasper, Møllgård, Kjeld, Greenway, Steven, Wakimoto, Hiroko, Gorham, Joshua M, Workman, Christopher T, Bendsen, Eske, Hansen, Niclas T, Rigina, Olga, Roque, Francisco S, Wiese, Cornelia, Christoffels, Vincent M, Roberts, Amy E, Smoot, Leslie B, Pu, William T, Donahoe, Patricia K, Tommerup, Niels, Brunak, Søren, Seidman, Christine E, Seidman, Jonathan G, Larsen, Lars A
Publicado 2010

Loss of RNA expression and allele-specific expression associated with congenital heart disease

por McKean, David M., Homsy, Jason, Wakimoto, Hiroko, Patel, Neil, Gorham, Joshua, DePalma, Steven R., Ware, James S., Zaidi, Samir, Ma, Wenji, Patel, Nihir, Lifton, Richard P., Chung, Wendy K., Kim, Richard, Shen, Yufeng, Brueckner, Martina, Goldmuntz, Elizabeth, Sharp, Andrew J., Seidman, Christine E., Gelb, Bruce D., Seidman, J. G.
Publicado 2016

An ancient founder mutation located between ROBO1 and ROBO2 is responsible for increased microtia risk in Amerindigenous populations

por Quiat, Daniel, Kim, Seong Won, Zhang, Qi, Morton, Sarah U., Pereira, Alexandre C., DePalma, Steven R., Willcox, Jon A. L., McDonough, Barbara, DeLaughter, Daniel M., Gorham, Joshua M., Curran, Justin J., Tumblin, Melissa, Nicolau, Yamileth, Artunduaga, Maria A., Quintanilla-Dieck, Lourdes, Osorno, Gabriel, Serrano, Luis, Hamdan, Usama, Eavey, Roland D., Seidman, Christine E., Seidman, J. G.
Publicado 2022

Ablation of lysophosphatidic acid receptor 1 attenuates hypertrophic cardiomyopathy in a mouse model

por Axelsson Raja, Anna, Wakimoto, Hiroko, DeLaughter, Daniel M., Reichart, Daniel, Gorham, Joshua, Conner, David A., Lun, Mingyue, Probst, Clemens K., Sakai, Norihiko, Knipe, Rachel S., Montesi, Sydney B., Shea, Barry, Adam, Leonard P., Leinwand, Leslie A., Wan, William, Choi, Esther Sue, Lindberg, Eric L., Patone, Giannino, Noseda, Michela, Hübner, Norbert, Seidman, Christine E., Tager, Andrew M., Seidman, J. G., Ho, Carolyn Y.
Publicado 2022

EM-mosaic detects mosaic point mutations that contribute to congenital heart disease

por Hsieh, Alexander, Morton, Sarah U., Willcox, Jon A. L., Gorham, Joshua M., Tai, Angela C., Qi, Hongjian, DePalma, Steven, McKean, David, Griffin, Emily, Manheimer, Kathryn B., Bernstein, Daniel, Kim, Richard W., Newburger, Jane W., Porter, George A., Srivastava, Deepak, Tristani-Firouzi, Martin, Brueckner, Martina, Lifton, Richard P., Goldmuntz, Elizabeth, Gelb, Bruce D., Chung, Wendy K., Seidman, Christine E., Seidman, J. G., Shen, Yufeng
Publicado 2020

GATA6 mutations in hiPSCs inform mechanisms for maldevelopment of the heart, pancreas, and diaphragm

por Sharma, Arun, Wasson, Lauren K, Willcox, Jon AL, Morton, Sarah U, Gorham, Joshua M, DeLaughter, Daniel M, Neyazi, Meraj, Schmid, Manuel, Agarwal, Radhika, Jang, Min Young, Toepfer, Christopher N, Ward, Tarsha, Kim, Yuri, Pereira, Alexandre C, DePalma, Steven R, Tai, Angela, Kim, Seongwon, Conner, David, Bernstein, Daniel, Gelb, Bruce D, Chung, Wendy K, Goldmuntz, Elizabeth, Porter, George, Tristani-Firouzi, Martin, Srivastava, Deepak, Seidman, Jonathan G, Seidman, Christine E
Publicado 2020

De Novo Copy Number Variants Identify New Genes and Loci in Isolated, Sporadic Tetralogy of Fallot

por Greenway, Steven C, Pereira, Alexandre C, Lin, Jennifer C, DePalma, Steven R, Israel, Samuel J, Mesquita, Sonia M, Ergul, Emel, Conta, Jessie R, Korn, Joshua M, McCarroll, Steven A, Gorham, Joshua M, Gabriel, Stacey, Altshuler, David A, de Lourdes Quintanilla-Dieck, Maria, Artunduaga, Maria Alexandra, Eavey, Roland D, Plenge, Robert M, Shadick, Nancy A, Weinblatt, Michael E, De Jager, Philip L, Hafler, David A, Breitbart, Roger E, Seidman, J G, Seidman, Christine E
Publicado 2009