Clinical development of metabolic inhibitors for oncology

por Lemberg, Kathryn M., Gori, Sadakatali S., Tsukamoto, Takashi, Rais, Rana, Slusher, Barbara S.
Publicado 2022

Lipid Peroxidation Produces a Diverse Mixture of Saturated and Unsaturated Aldehydes in Exhaled Breath That Can Serve as Biomarkers of Lung Cancer—A Review

por Sutaria, Saurin R., Gori, Sadakatali S., Morris, James D., Xie, Zhenzhen, Fu, Xiao-An, Nantz, Michael H.
Publicado 2022

D-DOPA Is a Potent, Orally Bioavailable, Allosteric Inhibitor of Glutamate Carboxypeptidase II

por Gori, Sadakatali S., Thomas, Ajit G., Pal, Arindom, Wiseman, Robyn, Ferraris, Dana V., Gao, Run-duo, Wu, Ying, Alt, Jesse, Tsukamoto, Takashi, Slusher, Barbara S., Rais, Rana
Publicado 2022

Glutamine Antagonist GA-607 Causes a Dramatic Accumulation of FGAR which can be used to Monitor Target Engagement

por Alt, Jesse, Gori, Sadakatali S., Lemberg, Kathryn M., Pal, Arindom, Veeravalli, Vijayabhaskar, Wu, Ying, Aguilar, Joanna M.H., Dash, Ranjeet P., Tenora, Lukáš, Majer, Pavel, Sun, Qi, Slusher, Barbara S., Rais, Rana
Publicado 2021

Discovery of tert-Butyl Ester Based 6-Diazo-5-oxo-l-norleucine Prodrugs for Enhanced Metabolic Stability and Tumor Delivery

por Novotná, Kateřina, Tenora, Lukáš, Prchalová, Eva, Paule, James, Alt, Jesse, Veeravalli, Vijay, Lam, Jenny, Wu, Ying, Šnajdr, Ivan, Gori, Sadakatali, Mettu, Vijaya Saradhi, Tsukamoto, Takashi, Majer, Pavel, Slusher, Barbara S., Rais, Rana
Publicado 2023

Topical SCD-153, a 4-methyl itaconate prodrug, for the treatment of alopecia areata

por Tsai, Jerry, Gori, Sadakatali, Alt, Jesse, Tiwari, Sandhya, Iyer, Jitesh, Talwar, Rashmi, Hinsu, Denish, Ahirwar, Kailash, Mohanty, Swayam, Khunt, Chintan, Sutariya, Brijesh, Jani, Kaushal, Venkatasubbaiah, Venkatesha, Patel, Ashok, Meghapara, Jasmin, Joshi, Kaushal, Sahu, Rajanikanta, Rana, Vijay, Nigade, Prashant, Talluri, Ravi S, Murty, Kadiyala V S N, Joshi, Kiritkumar, Ramanathan, Vikram, Li, Ang, Islam, Nasif, Snajdr, Ivan, Majer, Pavel, Rais, Rana, Slusher, Barbara S, Garza, Luis A
Publicado 2022