Neuronal cell death in neurodegenerative diseases: recurring themes around protein handling

por Gorman, Adrienne M
Publicado 2008

New insights into IRE1α activation and function in anti-tumor immunity

por Logue, Susan E., Gorman, Adrienne M., Samali, Afshin
Publicado 2022

Cellular Stress Responses: Cell Survival and Cell Death

por Fulda, Simone, Gorman, Adrienne M., Hori, Osamu, Samali, Afshin
Publicado 2010

Nerve Growth Factor in Cancer Cell Death and Survival

por Molloy, Niamh H., Read, Danielle E., Gorman, Adrienne M.
Publicado 2011

Inhibition by Anandamide of 6-Hydroxydopamine-Induced Cell Death in PC12 Cells

por Mnich, Katarzyna, Finn, David P., Dowd, Eilis, Gorman, Adrienne M.
Publicado 2010

Cell Stress and Cell Death

por Samali, Afshin, Fulda, Simone, Gorman, Adrienne M., Hori, Osamu, Srinivasula, Srinivasa M.
Publicado 2010

Binding Analysis of the Inositol-Requiring Enzyme 1 Kinase Domain

por Carlesso, Antonio, Chintha, Chetan, Gorman, Adrienne M., Samali, Afshin, Eriksson, Leif A.
Publicado 2018

Merits and pitfalls of conventional and covalent docking in identifying new hydroxyl aryl aldehyde like compounds as human IRE1 inhibitors

por Carlesso, Antonio, Chintha, Chetan, Gorman, Adrienne M., Samali, Afshin, Eriksson, Leif A.
Publicado 2019

Effect of Kinase Inhibiting RNase Attenuator (KIRA) Compounds on the Formation of Face-to-Face Dimers of Inositol-Requiring Enzyme 1: Insights from Computational Modeling

por Carlesso, Antonio, Chintha, Chetan, Gorman, Adrienne M., Samali, Afshin, Eriksson, Leif A.
Publicado 2019

Molecular modeling provides a structural basis for PERK inhibitor selectivity towards RIPK1

por Chintha, Chetan, Carlesso, Antonio, Gorman, Adrienne M., Samali, Afshin, Eriksson, Leif A.
Publicado 2020

Insights into the structure and function of the RNA ligase RtcB

por Moncan, Matthieu, Rakhsh-Khorshid, Hassan, Eriksson, Leif A., Samali, Afshin, Gorman, Adrienne M.
Publicado 2023

Regulation of lipid metabolism by the unfolded protein response

por Moncan, Matthieu, Mnich, Katarzyna, Blomme, Arnaud, Almanza, Aitor, Samali, Afshin, Gorman, Adrienne M.
Publicado 2021

An Emerging Role for the Unfolded Protein Response in Pancreatic Cancer

por Robinson, Claire M., Talty, Aaron, Logue, Susan E., Mnich, Katarzyna, Gorman, Adrienne M., Samali, Afshin
Publicado 2021

Disruption of microRNA Biogenesis Confers Resistance to ER Stress-Induced Cell Death Upstream of the Mitochondrion

por Cawley, Karen, Logue, Susan E., Gorman, Adrienne M., Zeng, Qingping, Patterson, John, Gupta, Sanjeev, Samali, Afshin
Publicado 2013

Unfolded proteins and endoplasmic reticulum stress in neurodegenerative disorders

por Doyle, Karen M, Kennedy, Donna, Gorman, Adrienne M, Gupta, Sanjeev, Healy, Sandra J M, Samali, Afshin
Publicado 2011

Application of a New Multiplexed Array for Rapid, Sensitive, Simultaneous and Quantitative Assessment of Spliced and Unspliced XBP1

por Creedican, Stuart, Talty, Aaron, Fitzgerald, Stephen P., Samali, Afshin, Richardson, Ciarán, Gorman, Adrienne M., Martin, Kenneth
Publicado 2019

The Unfolded Protein Response in Breast Cancer

por McGrath, Eoghan P., Logue, Susan E., Mnich, Katarzyna, Deegan, Shane, Jäger, Richard, Gorman, Adrienne M., Samali, Afshin
Publicado 2018

The stressosome, a caspase‐8‐activating signalling complex assembled in response to cell stress in an ATG5‐mediated manner

por Mnich, Katarzyna, Koryga, Izabela, Pakos‐Zebrucka, Karolina, Thomas, Melissa, Logue, Susan E., Eriksson, Leif A., Gorman, Adrienne M., Samali, Afshin
Publicado 2021

Endoplasmic Reticulum Stress-Regulated Chaperones as a Serum Biomarker Panel for Parkinson’s Disease

por Mnich, Katarzyna, Moghaddam, Shirin, Browne, Patrick, Counihan, Timothy, Fitzgerald, Stephen P., Martin, Kenneth, Richardson, Ciaran, Samali, Afshin, Gorman, Adrienne M.
Publicado 2022

HSPB1 facilitates ERK-mediated phosphorylation and degradation of BIM to attenuate endoplasmic reticulum stress-induced apoptosis

por Kennedy, Donna, Mnich, Katarzyna, Oommen, Deepu, Chakravarthy, Reka, Almeida-Souza, Leonardo, Krols, Michiel, Saveljeva, Svetlana, Doyle, Karen, Gupta, Sanjeev, Timmerman, Vincent, Janssens, Sophie, Gorman, Adrienne M, Samali, Afshin
Publicado 2017