QM/MM simulations provide insight into the mechanism of bioluminescence triggering in ctenophore photoproteins

por Molakarimi, Maryam, Mohseni, Ammar, Taghdir, Majid, Pashandi, Zaiddodine, Gorman, Michael A., Parker, Michael W., Naderi-Manesh, Hossein, Sajedi, Reza H.
Publicado 2017

Crystal structure of Streptococcus pneumoniae pneumolysin provides key insights into early steps of pore formation

por Lawrence, Sara L., Feil, Susanne C., Morton, Craig J., Farrand, Allison J., Mulhern, Terrence D., Gorman, Michael A., Wade, Kristin R., Tweten, Rodney K., Parker, Michael W.
Publicado 2015

Structural basis of allosteric and synergistic activation of AMPK by furan-2-phosphonic derivative C2 binding

por Langendorf, Christopher G., Ngoei, Kevin R. W., Scott, John W., Ling, Naomi X. Y., Issa, Sam M. A., Gorman, Michael A., Parker, Michael W., Sakamoto, Kei, Oakhill, Jonathan S., Kemp, Bruce E.
Publicado 2016

The Structural Basis for a Transition State That Regulates Pore Formation in a Bacterial Toxin

por Wade, Kristin R., Lawrence, Sara L., Farrand, Allison J., Hotze, Eileen M., Kuiper, Michael J., Gorman, Michael A., Christie, Michelle P., Panjikar, Santosh, Morton, Craig J., Parker, Michael W., Tweten, Rodney K.
Publicado 2019

Inhibitors of the Oncogenic PA2G4-MYCN Protein-Protein Interface

por Massudi, Hassina, Luo, Jie-Si, Holien, Jessica K., Gadde, Satyanarayana, Krishan, Sukriti, Herath, Mika, Koach, Jessica, Stevenson, Brendan W., Gorman, Michael A., Venkat, Pooja, Mayoh, Chelsea, Luo, Xue-Qun, Parker, Michael W., Cheung, Belamy B., Marshall, Glenn M.
Publicado 2023

From Knock-Out Phenotype to Three-Dimensional Structure of a Promising Antibiotic Target from Streptococcus pneumoniae

por Dogovski, Con, Gorman, Michael A., Ketaren, Natalia E., Praszkier, Judy, Zammit, Leanne M., Mertens, Haydyn D., Bryant, Gary, Yang, Ji, Griffin, Michael D. W., Pearce, F. Grant, Gerrard, Juliet A., Jameson, Geoffrey B., Parker, Michael W., Robins-Browne, Roy M., Perugini, Matthew A.
Publicado 2013