Modelling molecular interaction pathways using a two-stage identification algorithm

por Gormley, Padhraig, Li, Kang, Irwin, George W.
Publicado 2008

Migraine genetics: from genome-wide association studies to translational insights

por Gormley, Padhraig, Winsvold, Bendik S., Nyholt, Dale R., Kallela, Mikko, Chasman, Daniel I., Palotie, Aarno
Publicado 2016

Migraine, Stroke, and Cervical Arterial Dissection: Shared Genetics for a Triad of Brain Disorders With Vascular Involvement

por Daghals, Iyas, Sargurupremraj, Muralidharan, Danning, Rebecca, Gormley, Padhraig, Malik, Rainer, Amouyel, Philippe, Metso, Tiina, Pezzini, Alessandro, Kurth, Tobias, Debette, Stéphanie, Chasman, Daniel
Publicado 2022

Polygenic risk provides biological validity for the ICHD-3 criteria among Finnish migraine families

por Häppölä, Paavo, Gormley, Padhraig, Nuottamo, Marjo E, Artto, Ville, Sumelahti, Marja-Liisa, Nissilä, Markku, Keski-Säntti, Petra, Ilmavirta, Matti, Kaunisto, Mari A, Hämäläinen, Eija I, Ripatti, Samuli, Pirinen, Matti, Wessman, Maija, Palotie, Aarno, Kallela, Mikko
Publicado 2021

Simultaneous impairment of neuronal and metabolic function of mutated gephyrin in a patient with epileptic encephalopathy

por Dejanovic, Borislav, Djémié, Tania, Grünewald, Nora, Suls, Arvid, Kress, Vanessa, Hetsch, Florian, Craiu, Dana, Zemel, Matthew, Gormley, Padhraig, Lal, Dennis, Myers, Candace T, Mefford, Heather C, Palotie, Aarno, Helbig, Ingo, Meier, Jochen C, De Jonghe, Peter, Weckhuysen, Sarah, Schwarz, Guenter
Publicado 2015

Simultaneous impairment of neuronal and metabolic function of mutated gephyrin in a patient with epileptic encephalopathy

por Dejanovic, Borislav, Djémié, Tania, Grünewald, Nora, Suls, Arvid, Kress, Vanessa, Hetsch, Florian, Craiu, Dana, Zemel, Matthew, Gormley, Padhraig, Lal, Dennis, Myers, Candace T, Mefford, Heather C, Palotie, Aarno, Helbig, Ingo, Meier, Jochen C, De Jonghe, Peter, Weckhuysen, Sarah, Schwarz, Guenter
Publicado 2017

Shared genetic risk between migraine and coronary artery disease: A genome-wide analysis of common variants

por Winsvold, Bendik S., Bettella, Francesco, Witoelar, Aree, Anttila, Verneri, Gormley, Padhraig, Kurth, Tobias, Terwindt, Gisela M., Freilinger, Tobias M., Frei, Oleksander, Shadrin, Alexey, Wang, Yunpeng, Dale, Anders M., van den Maagdenberg, Arn M. J. M., Chasman, Daniel I., Nyholt, Dale R., Palotie, Aarno, Andreassen, Ole A., Zwart, John-Anker
Publicado 2017

Contribution of rare and common variants to intellectual disability in a sub-isolate of Northern Finland

por Kurki, Mitja I., Saarentaus, Elmo, Pietiläinen, Olli, Gormley, Padhraig, Lal, Dennis, Kerminen, Sini, Torniainen-Holm, Minna, Hämäläinen, Eija, Rahikkala, Elisa, Keski-Filppula, Riikka, Rauhala, Merja, Korpi-Heikkilä, Satu, Komulainen–Ebrahim, Jonna, Helander, Heli, Vieira, Päivi, Männikkö, Minna, Peltonen, Markku, Havulinna, Aki S., Salomaa, Veikko, Pirinen, Matti, Suvisaari, Jaana, Moilanen, Jukka S., Körkkö, Jarmo, Kuismin, Outi, Daly, Mark J., Palotie, Aarno
Publicado 2019

Heterogeneous contribution of microdeletions in the development of common generalised and focal epilepsies

por Pérez-Palma, Eduardo, Helbig, Ingo, Klein, Karl Martin, Anttila, Verneri, Horn, Heiko, Reinthaler, Eva Maria, Gormley, Padhraig, Ganna, Andrea, Byrnes, Andrea, Pernhorst, Katharina, Toliat, Mohammad R, Saarentaus, Elmo, Howrigan, Daniel P, Hoffman, Per, Miquel, Juan Francisco, De Ferrari, Giancarlo V, Nürnberg, Peter, Lerche, Holger, Zimprich, Fritz, Neubauer, Bern A, Becker, Albert J, Rosenow, Felix, Perucca, Emilio, Zara, Federico, Weber, Yvonne G, Lal, Dennis
Publicado 2017

Evaluation of Presumably Disease Causing SCN1A Variants in a Cohort of Common Epilepsy Syndromes

por Lal, Dennis, Reinthaler, Eva M., Dejanovic, Borislav, May, Patrick, Thiele, Holger, Lehesjoki, Anna-Elina, Schwarz, Günter, Riesch, Erik, Ikram, M. Arfan, van Duijn, Cornelia M., Uitterlinden, Andre G., Hofman, Albert, Steinböck, Hannelore, Gruber-Sedlmayr, Ursula, Neophytou, Birgit, Zara, Federico, Hahn, Andreas, Gormley, Padhraig, Becker, Felicitas, Weber, Yvonne G., Cilio, Maria Roberta, Kunz, Wolfram S., Krause, Roland, Zimprich, Fritz, Lemke, Johannes R., Nürnberg, Peter, Sander, Thomas, Lerche, Holger, Neubauer, Bernd A.
Publicado 2016

Gene family information facilitates variant interpretation and identification of disease-associated genes in neurodevelopmental disorders

por Lal, Dennis, May, Patrick, Perez-Palma, Eduardo, Samocha, Kaitlin E., Kosmicki, Jack A., Robinson, Elise B., Møller, Rikke S., Krause, Roland, Nürnberg, Peter, Weckhuysen, Sarah, De Jonghe, Peter, Guerrini, Renzo, Niestroj, Lisa M., Du, Juliana, Marini, Carla, Ware, James S., Kurki, Mitja, Gormley, Padhraig, Tang, Sha, Wu, Sitao, Biskup, Saskia, Poduri, Annapurna, Neubauer, Bernd A., Koeleman, Bobby P. C., Helbig, Katherine L., Weber, Yvonne G., Helbig, Ingo, Majithia, Amit R., Palotie, Aarno, Daly, Mark J.
Publicado 2020

Genome-wide Polygenic Burden of Rare Deleterious Variants in Sudden Unexpected Death in Epilepsy

por Leu, Costin, Balestrini, Simona, Maher, Bridget, Hernández-Hernández, Laura, Gormley, Padhraig, Hämäläinen, Eija, Heggeli, Kristin, Schoeler, Natasha, Novy, Jan, Willis, Joseph, Plagnol, Vincent, Ellis, Rachael, Reavey, Eleanor, O'Regan, Mary, Pickrell, William O., Thomas, Rhys H., Chung, Seo-Kyung, Delanty, Norman, McMahon, Jacinta M., Malone, Stephen, Sadleir, Lynette G., Berkovic, Samuel F., Nashef, Lina, Zuberi, Sameer M., Rees, Mark I., Cavalleri, Gianpiero L., Sander, Josemir W., Hughes, Elaine, Helen Cross, J., Scheffer, Ingrid E., Palotie, Aarno, Sisodiya, Sanjay M.
Publicado 2015

Pitfalls in genetic testing: the story of missed SCN1A mutations

por Djémié, Tania, Weckhuysen, Sarah, von Spiczak, Sarah, Carvill, Gemma L., Jaehn, Johanna, Anttonen, Anna‐Kaisa, Brilstra, Eva, Caglayan, Hande S., de Kovel, Carolien G., Depienne, Christel, Gaily, Eija, Gennaro, Elena, Giraldez, Beatriz G., Gormley, Padhraig, Guerrero‐López, Rosa, Guerrini, Renzo, Hämäläinen, Eija, Hartmann, Corinna, Hernandez‐Hernandez, Laura, Hjalgrim, Helle, Koeleman, Bobby P. C., Leguern, Eric, Lehesjoki, Anna‐Elina, Lemke, Johannes R., Leu, Costin, Marini, Carla, McMahon, Jacinta M., Mei, Davide, Møller, Rikke S., Muhle, Hiltrud, Myers, Candace T., Nava, Caroline, Serratosa, Jose M., Sisodiya, Sanjay M., Stephani, Ulrich, Striano, Pasquale, van Kempen, Marjan J. A., Verbeek, Nienke E., Usluer, Sunay, Zara, Federico, Palotie, Aarno, Mefford, Heather C., Scheffer, Ingrid E., De Jonghe, Peter, Helbig, Ingo, Suls, Arvid
Publicado 2016

Genetic analysis for a shared biological basis between migraine and coronary artery disease

por Winsvold, Bendik S., Nelson, Christopher P., Malik, Rainer, Gormley, Padhraig, Anttila, Verneri, Vander Heiden, Jason, Elliott, Katherine S., Jacobsen, Line M., Palta, Priit, Amin, Najaf, de Vries, Boukje, Hämäläinen, Eija, Freilinger, Tobias, Ikram, M. Arfan, Kessler, Thorsten, Koiranen, Markku, Ligthart, Lannie, McMahon, George, Pedersen, Linda M., Willenborg, Christina, Won, Hong-Hee, Olesen, Jes, Artto, Ville, Assimes, Themistocles L., Blankenberg, Stefan, Boomsma, Dorret I., Cherkas, Lynn, Davey Smith, George, Epstein, Stephen E., Erdmann, Jeanette, Ferrari, Michel D., Göbel, Hartmut, Hall, Alistair S., Jarvelin, Marjo-Riitta, Kallela, Mikko, Kaprio, Jaakko, Kathiresan, Sekar, Lehtimäki, Terho, McPherson, Ruth, März, Winfried, Nyholt, Dale R., O'Donnell, Christopher J., Quaye, Lydia, Rader, Daniel J., Raitakari, Olli, Roberts, Robert, Schunkert, Heribert, Schürks, Markus, Stewart, Alexandre F.R., Terwindt, Gisela M., Thorsteinsdottir, Unnur, van den Maagdenberg, Arn M.J.M., van Duijn, Cornelia, Wessman, Maija, Kurth, Tobias, Kubisch, Christian, Dichgans, Martin, Chasman, Daniel I., Cotsapas, Chris, Zwart, John-Anker, Samani, Nilesh J., Palotie, Aarno
Publicado 2015

Genome-wide analysis of 102,084 migraine cases identifies 123 risk loci and subtype-specific risk alleles

por Hautakangas, Heidi, Winsvold, Bendik S., Ruotsalainen, Sanni E., Bjornsdottir, Gyda, Harder, Aster V. E., Kogelman, Lisette J. A., Thomas, Laurent F., Noordam, Raymond, Benner, Christian, Gormley, Padhraig, Artto, Ville, Banasik, Karina, Bjornsdottir, Anna, Boomsma, Dorret I., Brumpton, Ben M., Burgdorf, Kristoffer Sølvsten, Buring, Julie E., Chalmer, Mona Ameri, de Boer, Irene, Dichgans, Martin, Erikstrup, Christian, Färkkilä, Markus, Garbrielsen, Maiken Elvestad, Ghanbari, Mohsen, Hagen, Knut, Häppölä, Paavo, Hottenga, Jouke-Jan, Hrafnsdottir, Maria G., Hveem, Kristian, Johnsen, Marianne Bakke, Kähönen, Mika, Kristoffersen, Espen S., Kurth, Tobias, Lehtimäki, Terho, Lighart, Lannie, Magnusson, Sigurdur H., Malik, Rainer, Pedersen, Ole Birger, Pelzer, Nadine, Penninx, Brenda W. J. H., Ran, Caroline, Ridker, Paul M., Rosendaal, Frits R., Sigurdardottir, Gudrun R., Skogholt, Anne Heidi, Sveinsson, Olafur A., Thorgeirsson, Thorgeir E., Ullum, Henrik, Vijfhuizen, Lisanne S., Widén, Elisabeth, van Dijk, Ko Willems, Aromaa, Arpo, Belin, Andrea Carmine, Freilinger, Tobias, Ikram, M. Arfan, Järvelin, Marjo-Riitta, Raitakari, Olli T., Terwindt, Gisela M., Kallela, Mikko, Wessman, Maija, Olesen, Jes, Chasman, Daniel I., Nyholt, Dale R., Stefánsson, Hreinn, Stefansson, Kari, van den Maagdenberg, Arn M. J. M., Hansen, Thomas Folkmann, Ripatti, Samuli, Zwart, John-Anker, Palotie, Aarno, Pirinen, Matti
Publicado 2022

Genome-wide meta-analysis identifies new susceptibility loci for migraine

por Anttila, Verneri, Winsvold, Bendik S., Gormley, Padhraig, Kurth, Tobias, Bettella, Francesco, McMahon, George, Kallela, Mikko, Malik, Rainer, de Vries, Boukje, Terwindt, Gisela, Medland, Sarah E., Todt, Unda, McArdle, Wendy L., Quaye, Lydia, Koiranen, Markku, Ikram, M. Arfan, Lehtimäki, Terho, Stam, Anine H., Ligthart, Lannie, Wedenoja, Juho, Dunham, Ian, Neale, Benjamin M., Palta, Priit, Hamalainen, Eija, Schürks, Markus, Rose, Lynda M, Buring, Julie E., Ridker, Paul M., Steinberg, Stacy, Stefansson, Hreinn, Jakobsson, Finnbogi, Lawlor, Debbie A., Evans, David M., Ring, Susan M., Färkkilä, Markus, Artto, Ville, Kaunisto, Mari A, Freilinger, Tobias, Schoenen, Jean, Frants, Rune R., Pelzer, Nadine, Weller, Claudia M., Zielman, Ronald, Heath, Andrew C., Madden, Pamela A.F., Montgomery, Grant W., Martin, Nicholas G., Borck, Guntram, Göbel, Hartmut, Heinze, Axel, Heinze-Kuhn, Katja, Williams, Frances M.K., Hartikainen, Anna-Liisa, Pouta, Anneli, van den Ende, Joyce, Uitterlinden, Andre G., Hofman, Albert, Amin, Najaf, Hottenga, Jouke-Jan, Vink, Jacqueline M., Heikkilä, Kauko, Alexander, Michael, Muller-Myhsok, Bertram, Schreiber, Stefan, Meitinger, Thomas, Wichmann, Heinz Erich, Aromaa, Arpo, Eriksson, Johan G., Traynor, Bryan, Trabzuni, Daniah, Rossin, Elizabeth, Lage, Kasper, Jacobs, Suzanne B.R., Gibbs, J. Raphael, Birney, Ewan, Kaprio, Jaakko, Penninx, Brenda W., Boomsma, Dorret I., van Duijn, Cornelia, Raitakari, Olli, Jarvelin, Marjo-Riitta, Zwart, John-Anker, Cherkas, Lynn, Strachan, David P., Kubisch, Christian, Ferrari, Michel D., van den Maagdenberg, Arn M.J.M., Dichgans, Martin, Wessman, Maija, Smith, George Davey, Stefansson, Kari, Daly, Mark J., Nyholt, Dale R., Chasman, Daniel, Palotie, Aarno
Publicado 2013