MDB-25. LARGE CELL/ANAPLASTIC MEDULLOBLASTOMA REPRESENTS MORE THAN ONE DISEASE ENTITY

por Krause, Katharina, Goschzik, Tobias, Doerner, Evelyn, Pietsch, Torsten
Publicado 2023

MEDB-61. Genetic alterations ofTP53 andOTX2 indicate increased risk of relapse in WNT medulloblastomas

por Goschzik, Tobias, Mynarek, Martin, Dörner, Evelyn, Aretz, Stefan, Rutkowski, Stefan, Pietsch, Torsten
Publicado 2022

MEDB-68. Analysis of telomeres length and Alternative Lengthening of Telomeres (ALT) in molecular subgroups of infant medulloblastoma

por Buttarelli, Francesca Romana, Minasi, Simone, Garrè, Maria Luisa, Massimino, Maura, Biassoni, Veronica, Goschzik, Tobias, Pietsch, Torsten, Giangaspero, Felice
Publicado 2022

MEDB-35. Relationship between genetic profile, histology, clinical features and long-term outcome in young children medulloblastoma (YCMB) treated with upfront high dose chemothera...

por Garrè, Maria Luisa, Massimino, Maura, Buttarelli, Francesca Romana, Gandola, Lorenza, Barra, Salvina, Giangaspero, Felice, Goschzik, Tobias, Biassoni, Veronica, Pastorino, Lorenza, Pistorio, Angela, Pietsch, Torsten
Publicado 2022

Prognostic effect of whole chromosomal aberration signatures in standard-risk, non-WNT/non-SHH medulloblastoma: a retrospective, molecular analysis of the HIT-SIOP PNET 4 trial

por Goschzik, Tobias, Schwalbe, Edward C, Hicks, Debbie, Smith, Amanda, zur Muehlen, Anja, Figarella-Branger, Dominique, Doz, François, Rutkowski, Stefan, Lannering, Birgitta, Pietsch, Torsten, Clifford, Steven C
Publicado 2018

RARE-12. Pineoblastoma of children and young adults in a national population: An analysis of the HIT-MED study cohort

por Yuan, Mathias, Mynarek, Martin, Goschzik, Tobias, Pfaff, Elke, Kortmann, Rolf, Bison, Brigitte, Warmuth-Metz, Monika, Schiller, Ulrich, Hagel, Christian, Obrecht, Denise, Benesch, Martin, Pfister, Stefan M, Pietsch, Torsten, Rutkowski, Stefan
Publicado 2022

Genetic alterations of TP53 and OTX2 indicate increased risk of relapse in WNT medulloblastomas

por Goschzik, Tobias, Mynarek, Martin, Doerner, Evelyn, Schenk, Alina, Spier, Isabel, Warmuth-Metz, Monika, Bison, Brigitte, Obrecht, Denise, Struve, Nina, Kortmann, Rolf-Dieter, Schmid, Matthias, Aretz, Stefan, Rutkowski, Stefan, Pietsch, Torsten
Publicado 2022

Biomarker-driven stratification of disease-risk in non-metastatic medulloblastoma: Results from the multi-center HIT-SIOP-PNET4 clinical trial

por Clifford, Steven C., Lannering, Birgitta, Schwalbe, Ed C., Hicks, Debbie, O' Toole, Kieran, Nicholson, Sarah Leigh, Goschzik, Tobias, zur Mühlen, Anja, Figarella-Branger, Dominique, Doz, François, Rutkowski, Stefan, Gustafsson, Göran, Pietsch, Torsten
Publicado 2015

EMBR-25. GENOME-WIDE GENETIC AND EPIGENETIC ASSESSMENT OF GROUP 4 MEDULLOBLASTOMA FOR IMPROVED, BIOMARKER DRIVEN, PROGNOSTICATION AND RISK-STRATIFICATION

por Goddard, Jack, Castle, Jemma, Southworth, Emily, Crosier, Stephen, Martin-Guerrero, Idoia, Garcia-Ariza, Miguel, Navajas, Aurora, Bourdeaut, Franck, Dufour, Christelle, Goschzik, Tobias, Pietsch, Torsten, Williamson, Dan, Bailey, Simon, Schwalbe, Ed, Clifford, Steven, Hicks, Debbie
Publicado 2021

Minimal methylation classifier (MIMIC): A novel method for derivation and rapid diagnostic detection of disease-associated DNA methylation signatures

por Schwalbe, E. C., Hicks, D., Rafiee, G., Bashton, M., Gohlke, H., Enshaei, A., Potluri, S., Matthiesen, J., Mather, M., Taleongpong, P., Chaston, R., Silmon, A., Curtis, A., Lindsey, J. C., Crosier, S., Smith, A. J., Goschzik, T., Doz, F., Rutkowski, S., Lannering, B., Pietsch, T., Bailey, S., Williamson, D., Clifford, S. C.
Publicado 2017

Molecular characterisation defines clinically-actionable heterogeneity within Group 4 medulloblastoma and improves disease risk-stratification

por Goddard, Jack, Castle, Jemma, Southworth, Emily, Fletcher, Anya, Crosier, Stephen, Martin-Guerrero, Idoia, García-Ariza, Miguel, Navajas, Aurora, Masliah-Planchon, Julien, Bourdeaut, Franck, Dufour, Christelle, Ayrault, Olivier, Goschzik, Tobias, Pietsch, Torsten, Sill, Martin, Pfister, Stefan M., Rutkowski, Stefan, Richardson, Stacey, Hill, Rebecca M., Williamson, Daniel, Bailey, Simon, Schwalbe, Edward C., Clifford, Steven C., Hicks, Debbie
Publicado 2023

Prognostic significance of clinical, histopathological, and molecular characteristics of medulloblastomas in the prospective HIT2000 multicenter clinical trial cohort

por Pietsch, Torsten, Schmidt, Rene, Remke, Marc, Korshunov, Andrey, Hovestadt, Volker, Jones, David T. W., Felsberg, Jörg, Kaulich, Kerstin, Goschzik, Tobias, Kool, Marcel, Northcott, Paul A., von Hoff, Katja, von Bueren, André O., Friedrich, Carsten, Mynarek, Martin, Skladny, Heyko, Fleischhack, Gudrun, Taylor, Michael D., Cremer, Friedrich, Lichter, Peter, Faldum, Andreas, Reifenberger, Guido, Rutkowski, Stefan, Pfister, Stefan M.
Publicado 2014

Identification of low and very high-risk patients with non-WNT/non-SHH medulloblastoma by improved clinico-molecular stratification of the HIT2000 and I-HIT-MED cohorts

por Mynarek, Martin, Obrecht, Denise, Sill, Martin, Sturm, Dominik, Kloth-Stachnau, Katja, Selt, Florian, Ecker, Jonas, von Hoff, Katja, Juhnke, Björn-Ole, Goschzik, Tobias, Pietsch, Torsten, Bockmayr, Michael, Kool, Marcel, von Deimling, Andreas, Witt, Olaf, Schüller, Ulrich, Benesch, Martin, Gerber, Nicolas U., Sahm, Felix, Jones, David T. W., Korshunov, Andrey, Pfister, Stefan M., Rutkowski, Stefan, Milde, Till
Publicado 2022

MEDB-04. Young children with metastatic medulloblastoma: frequent requirement for radiotherapy in children with non-WNT/non-SHH medulloblastoma despite highly intensified chemother...

por Mynarek, Martin, Goschzik, Tobias, Kool, Marcel, von Hoff, Katja, Ottensmeier, Holger, Warmuth-Metz, Monika, Bison, Brigitte, Sill, Martin, Rushing, Elisabeth Jane, Hasselblatt, Martin, Koch, Arend, Schüller, Ulrich, von Deimling, Andreas, Riemenschneider, Markus J, Dohmen, Hildegard, Monoranu, Camelia-Maria, Sommer, Clemens, Staszewski, Ori, Mawrin, Christian, Schittenhelm, Jens, Brück, Wolfgang, Filipski, Katharina, Hartmann, Christian, Meinhardt, Matthias, Pietschmann, Klaus, Haberler, Christine, Slavc, Irene, Gerber, Nicolas U, Grotzer, Michael, Benesch, Martin, Schlegel, Paul-Gerhardt, Deinlein, Frank, Bode, Udo, von Bueren, André O, Friedrich, Carsten, Obrecht, Denise, Fleischhack, Gudrun, Kwiecien, Robert, Faldum, Andreas, Kortmann, Rolf-Dieter, Pietsch, Torsten, Pfister, Stefan, Rutkowski, Stefan
Publicado 2022