Molecular basis of titin exon exclusion by RBM20 and the novel titin splice regulator PTB4

por Dauksaite, Vita, Gotthardt, Michael
Publicado 2018

Cardiac sarcomere mechanics in health and disease

por Crocini, Claudia, Gotthardt, Michael
Publicado 2021

Assessment of nanoindentation in stiffness measurement of soft biomaterials: kidney, liver, spleen and uterus

por Wu, Guanlin, Gotthardt, Michael, Gollasch, Maik
Publicado 2020

Author Correction: Assessment of nanoindentation in stiffness measurement of soft biomaterials: kidney, liver, spleen and uterus

por Wu, Guanlin, Gotthardt, Michael, Gollasch, Maik
Publicado 2021

RBM20-Related Cardiomyopathy: Current Understanding and Future Options

por Koelemen, Jan, Gotthardt, Michael, Steinmetz, Lars M., Meder, Benjamin
Publicado 2021

The IgCAM CAR Regulates Gap Junction-Mediated Coupling on Embryonic Cardiomyocytes and Affects Their Beating Frequency

por Matthaeus, Claudia, Jüttner, René, Gotthardt, Michael, Rathjen, Fritz G.
Publicado 2022

M line–deficient titin causes cardiac lethality through impaired maturation of the sarcomere

por Weinert, Stefanie, Bergmann, Nora, Luo, Xiuju, Erdmann, Bettina, Gotthardt, Michael
Publicado 2006

Titin visualization in real time reveals an unexpected level of mobility within and between sarcomeres

por da Silva Lopes, Katharina, Pietas, Agnieszka, Radke, Michael H., Gotthardt, Michael
Publicado 2011

Reducing RBM20 activity improves diastolic dysfunction and cardiac atrophy

por Hinze, Florian, Dieterich, Christoph, Radke, Michael H., Granzier, Henk, Gotthardt, Michael
Publicado 2016

Drug discovery with an RBM20 dependent titin splice reporter identifies cardenolides as lead structures to improve cardiac filling

por Liss, Martin, Radke, Michael H., Eckhard, Jamina, Neuenschwander, Martin, Dauksaite, Vita, von Kries, Jens-Peter, Gotthardt, Michael
Publicado 2018

Metformin improves diastolic function in an HFpEF-like mouse model by increasing titin compliance

por Slater, Rebecca E., Strom, Joshua G., Methawasin, Mei, Liss, Martin, Gotthardt, Michael, Sweitzer, Nancy, Granzier, Henk L.
Publicado 2019

A single‐cell RNA labeling strategy for measuring stress response upon tissue dissociation

por Neuschulz, Anika, Bakina, Olga, Badillo‐Lisakowski, Victor, Olivares‐Chauvet, Pedro, Conrad, Thomas, Gotthardt, Michael, Kettenmann, Helmut, Junker, Jan Philipp
Publicado 2022

Visualization of β-adrenergic receptor dynamics and differential localization in cardiomyocytes

por Bathe-Peters, Marc, Gmach, Philipp, Boltz, Horst-Holger, Einsiedel, Jürgen, Gotthardt, Michael, Hübner, Harald, Gmeiner, Peter, Lohse, Martin J., Annibale, Paolo
Publicado 2021

Podocyte-Specific Deletion of Murine CXADR Does Not Impair Podocyte Development, Function or Stress Response

por Schell, Christoph, Kretz, Oliver, Bregenzer, Andreas, Rogg, Manuel, Helmstädter, Martin, Lisewski, Ulrike, Gotthardt, Michael, Tharaux, Pierre-Louis, Huber, Tobias B., Grahammer, Florian
Publicado 2015

The tight junction protein CAR regulates cardiac conduction and cell–cell communication

por Lisewski, Ulrike, Shi, Yu, Wrackmeyer, Uta, Fischer, Robert, Chen, Chen, Schirdewan, Alexander, Jüttner, Rene, Rathjen, Fritz, Poller, Wolfgang, Radke, Michael H., Gotthardt, Michael
Publicado 2008

Moderate inappropriately high aldosterone/NaCl constellation in mice: cardiovascular effects and the role of cardiovascular epidermal growth factor receptor

por Schreier, Barbara, Rabe, Sindy, Winter, Sabrina, Ruhs, Stefanie, Mildenberger, Sigrid, Schneider, Bettina, Sibilia, Maria, Gotthardt, Michael, Kempe, Sabine, Mäder, Karsten, Grossmann, Claudia, Gekle, Michael
Publicado 2014

The cell adhesion protein CAR is a negative regulator of synaptic transmission

por Wrackmeyer, Uta, Kaldrack, Joanna, Jüttner, René, Pannasch, Ulrike, Gimber, Niclas, Freiberg, Fabian, Purfürst, Bettina, Kainmueller, Dagmar, Schmitz, Dietmar, Haucke, Volker, Rathjen, Fritz G., Gotthardt, Michael
Publicado 2019

Deconstructing sarcomeric structure–function relations in titin-BioID knock-in mice

por Rudolph, Franziska, Fink, Claudia, Hüttemeister, Judith, Kirchner, Marieluise, Radke, Michael H., Lopez Carballo, Jacobo, Wagner, Eva, Kohl, Tobias, Lehnart, Stephan E., Mertins, Philipp, Gotthardt, Michael
Publicado 2020

RBM20 phosphorylation and its role in nucleocytoplasmic transport and cardiac pathogenesis

por Zhang, Yanghai, Wang, Chunyan, Sun, Mingming, Jin, Yutong, Braz, Camila Urbano, Khatib, Hasan, Hacker, Timothy A., Liss, Martin, Gotthardt, Michael, Granzier, Henk, Ge, Ying, Guo, Wei
Publicado 2022

Deleting Titin’s C-Terminal PEVK Exons Increases Passive Stiffness, Alters Splicing, and Induces Cross-Sectional and Longitudinal Hypertrophy in Skeletal Muscle

por van der Pijl, Robbert J., Hudson, Brian, Granzier-Nakajima, Tomotaroh, Li, Frank, Knottnerus, Anne M., Smith, John, Chung, Charles S., Gotthardt, Michael, Granzier, Henk L., Ottenheijm, Coen A. C.
Publicado 2020