Generation of permanent neonatal diabetes mellitus dogs with glucokinase point mutations through base editing

por Wang, Xiaomin, Liang, Yanhui, Zhao, Jianping, Li, Yuan, Gou, Shixue, Zheng, Min, Zhou, Juanjuan, Zhang, Quanjun, Mi, Jidong, Lai, Liangxue
Publicado 2021

Author Correction: Generation of permanent neonatal diabetes mellitus dogs with glucokinase point mutations through base editing

por Wang, Xiaomin, Liang, Yanhui, Zhao, Jianping, Li, Yuan, Gou, Shixue, Zheng, Min, Zhou, Juanjuan, Zhang, Quanjun, Mi, Jidong, Lai, Liangxue
Publicado 2021

VCFshiny: an R/Shiny application for interactively analyzing and visualizing genetic variants

por Chen, Tao, Tang, Chengcheng, Zheng, Wei, Qian, Yanan, Chen, Min, Zou, Qingjian, Jin, Yinge, Wang, Kepin, Zhou, Xiaoqing, Gou, Shixue, Lai, Liangxue
Publicado 2023

Precise genome editing of the Kozak sequence enables bidirectional and quantitative modulation of protein translation to anticipated levels without affecting transcription

por Xie, Jingke, Zhuang, Zhenpeng, Gou, Shixue, Zhang, Quanjun, Wang, Xia, Lan, Ting, Lian, Meng, Li, Nan, Liang, Yanhui, Ouyang, Zhen, Ye, Yinghua, Wu, Han, Lai, Liangxue, Wang, Kepin
Publicado 2023

Evaluation of guide-free Cas9-induced genomic damage and transcriptome changes in pig embryos

por Ge, Weikai, Zhao, Xiaozhu, Gou, Shixue, Jin, Qin, Chen, Fangbing, Ouyang, Zhen, Lai, Chengdan, Cui, Tao, Mai, Baoyi, Lu, Sijia, Zhong, Kexin, Liang, Yanhui, Chen, Tao, Wu, Han, Li, Nan, Ye, Yinghua, Lai, Liangxue, Wang, Kepin
Publicado 2023

In vivo genome editing in mouse restores dystrophin expression in Duchenne muscular dystrophy patient muscle fibers

por Chen, Menglong, Shi, Hui, Gou, Shixue, Wang, Xiaomin, Li, Lei, Jin, Qin, Wu, Han, Zhang, Huili, Li, Yaqin, Wang, Liang, Li, Huan, Lin, Jinfu, Guo, Wenjing, Jiang, Zhiwu, Yang, Xiaoyu, Xu, Anding, Zhu, Yuling, Zhang, Cheng, Lai, Liangxue, Li, Xiaoping
Publicado 2021

AGBE: a dual deaminase-mediated base editor by fusing CGBE with ABE for creating a saturated mutant population with multiple editing patterns

por Liang, Yanhui, Xie, Jingke, Zhang, Quanjun, Wang, Xiaomin, Gou, Shixue, Lin, Lihui, Chen, Tao, Ge, Weikai, Zhuang, Zhenpeng, Lian, Meng, Chen, Fangbing, Li, Nan, Ouyang, Zhen, Lai, Chengdan, Liu, Xiaoyi, Li, Lei, Ye, Yinghua, Wu, Han, Wang, Kepin, Lai, Liangxue
Publicado 2022

Doxycycline-dependent Cas9-expressing pig resources for conditional in vivo gene nullification and activation

por Jin, Qin, Liu, Xiaoyi, Zhuang, Zhenpeng, Huang, Jiayuan, Gou, Shixue, Shi, Hui, Zhao, Yu, Ouyang, Zhen, Liu, Zhaoming, Li, Lei, Mao, Junjie, Ge, Weikai, Chen, Fangbing, Yu, Manya, Guan, Yezhi, Ye, Yinghua, Tang, Chengcheng, Huang, Ren, Wang, Kepin, Lai, Liangxue
Publicado 2023

ACBE, a new base editor for simultaneous C-to-T and A-to-G substitutions in mammalian systems

por Xie, Jingke, Huang, Xingyun, Wang, Xia, Gou, Shixue, Liang, Yanhui, Chen, Fangbing, Li, Nan, Ouyang, Zhen, Zhang, Quanjun, Ge, Weikai, Jin, Qin, Shi, Hui, Zhuang, Zhenpeng, Zhao, Xiaozhu, Lian, Meng, Wang, Jiaowei, Ye, Yinghua, Quan, Longquan, Wu, Han, Wang, Kepin, Lai, Liangxue
Publicado 2020

Efficient base editing for multiple genes and loci in pigs using base editors

por Xie, Jingke, Ge, Weikai, Li, Nan, Liu, Qishuai, Chen, Fangbing, Yang, Xiaoyu, Huang, Xingyun, Ouyang, Zhen, Zhang, Quanjun, Zhao, Yu, Liu, Zhaoming, Gou, Shixue, Wu, Han, Lai, Chengdan, Fan, Nana, Jin, Qin, Shi, Hui, Liang, Yanhui, Lan, Ting, Quan, Longquan, Li, Xiaoping, Wang, Kepin, Lai, Liangxue
Publicado 2019

Multiplexed base editing through Cas12a variant-mediated cytosine and adenine base editors

por Chen, Fangbing, Lian, Meng, Ma, Bingxiu, Gou, Shixue, Luo, Xian, Yang, Kaiming, Shi, Hui, Xie, Jingke, Ge, Weika, Ouyang, Zhen, Lai, Chengdan, Li, Nan, Zhang, Quanjun, Jin, Qin, Liang, Yanhui, Chen, Tao, Wang, Jiaowei, Zhao, Xiaozhu, Li, Lei, Yu, Manya, Ye, Yinghua, Wang, Kepin, Wu, Han, Lai, Liangxue
Publicado 2022

Human induced-T-to-natural killer cells have potent anti-tumour activities

por Jiang, Zhiwu, Qin, Le, Tang, Yuou, Liao, Rui, Shi, Jingxuan, He, Bingjia, Li, Shanglin, Zheng, Diwei, Cui, Yuanbin, Wu, Qiting, Long, Youguo, Yao, Yao, Wei, Zhihui, Hong, Qilan, Wu, Yi, Mai, Yuanbang, Gou, Shixue, Li, Xiaoping, Weinkove, Robert, Norton, Sam, Luo, Wei, Feng, Weineng, Zhou, Hongsheng, Liu, Qifa, Chen, Jiekai, Lai, Liangxue, Chen, Xinwen, Pei, Duanqing, Graf, Thomas, Liu, Xingguo, Li, Yangqiu, Liu, Pentao, Zhang, Zhenfeng, Li, Peng
Publicado 2022