Icotinib, Almonertinib, and Olmutinib: A 2D Similarity/Docking-Based Study to Predict the Potential Binding Modes and Interactions into EGFR

por Almalki, Faisal A., Shawky, Ahmed M., Abdalla, Ashraf N., Gouda, Ahmed M.
Publicado 2021

Globally Approved EGFR Inhibitors: Insights into Their Syntheses, Target Kinases, Biological Activities, Receptor Interactions, and Metabolism

por Abourehab, Mohammed A. S., Alqahtani, Alaa M., Youssif, Bahaa G. M., Gouda, Ahmed M.
Publicado 2021

Pyrrolizine/indolizine-bearing (un)substituted isoindole moiety: design, synthesis, antiproliferative and MDR reversal activities, and in silico studies

por AbdelSamad, Amr L., El-Saadi, Mohammed T., Gouda, Ahmed M., AboulMagd, Asmaa M.
Publicado 2023

Pharmacophore-based virtual screening, synthesis, biological evaluation, and molecular docking study of novel pyrrolizines bearing urea/thiourea moieties with potential cytotoxicit...

por Shawky, Ahmed M., Ibrahim, Nashwa A., Abourehab, Mohammed A. S., Abdalla, Ashraf N., Gouda, Ahmed M.
Publicado 2020

Novel pyrrolizines bearing 3,4,5-trimethoxyphenyl moiety: design, synthesis, molecular docking, and biological evaluation as potential multi-target cytotoxic agents

por Shawky, Ahmed M., Ibrahim, Nashwa A., Abdalla, Ashraf N., Abourehab, Mohammed A. S., Gouda, Ahmed M.
Publicado 2021

A Comprehensive Overview of Globally Approved JAK Inhibitors

por Shawky, Ahmed M., Almalki, Faisal A., Abdalla, Ashraf N., Abdelazeem, Ahmed H., Gouda, Ahmed M.
Publicado 2022

In Silico Approach Using Free Software to Optimize the Antiproliferative Activity and Predict the Potential Mechanism of Action of Pyrrolizine-Based Schiff Bases

por Almalki, Faisal A., Abdalla, Ashraf N., Shawky, Ahmed M., El Hassab, Mahmoud A., Gouda, Ahmed M.
Publicado 2021

Design, Synthesis, and Biological Evaluation of Some Novel Pyrrolizine Derivatives as COX Inhibitors with Anti-Inflammatory/Analgesic Activities and Low Ulcerogenic Liability

por Gouda, Ahmed M., Ali, Hamed I., Almalki, Waleed H., Azim, Mohamed A., Abourehab, Mohammed A. S., Abdelazeem, Ahmed H.
Publicado 2016

Pyrrolizine/Indolizine-NSAID Hybrids: Design, Synthesis, Biological Evaluation, and Molecular Docking Studies

por Abourehab, Mohammed A. S., Alqahtani, Alaa M., Almalki, Faisal A., Zaher, Dana M., Abdalla, Ashraf N., Gouda, Ahmed M., Beshr, Eman A. M.
Publicado 2021

Computational Analysis of Deleterious SNPs in NRAS to Assess Their Potential Correlation With Carcinogenesis

por Behairy, Mohammed Y., Soltan, Mohamed A., Adam, Mohamed S., Refaat, Ahmed M., Ezz, Ehab M., Albogami, Sarah, Fayad, Eman, Althobaiti, Fayez, Gouda, Ahmed M., Sileem, Ashraf E., Elfaky, Mahmoud A., Darwish, Khaled M., Alaa Eldeen, Muhammad
Publicado 2022

Synthesis, Anticancer Assessment, and Molecular Docking of Novel Chalcone-Thienopyrimidine Derivatives in HepG2 and MCF-7 Cell Lines

por Safwat, Ghada M., Hassanin, Kamel M. A., Mohammed, Eman T., Ahmed, Essam Kh., Abdel Rheim, Mahmoud R., Ameen, Mohamed A., Abdel-Aziz, Mohamed, Gouda, Ahmed M., Peluso, Ilaria, Almeer, Rafa, Abdel-Daim, Mohamed M., Abdel-Wahab, Ahmed
Publicado 2021

Synergistic Anti Leukemia Effect of a Novel Hsp90 and a Pan Cyclin Dependent Kinase Inhibitors

por Abdalla, Ashraf N., Abdallah, Mohamed E., Aslam, Akhmed, Bader, Ammar, Vassallo, Antonio, Tommasi, Nunziatina De, Malki, Waleed H., Gouda, Ahmed M., Mukhtar, Mohammed H., El-Readi, Mahmoud Zaki, Alkahtani, Hamad M., Abdel-Aziz, Alaa A.-M., El-Azab, Adel S.
Publicado 2020

Integration of immunoinformatics and cheminformatics to design and evaluate a multitope vaccine against Klebsiella pneumoniae and Pseudomonas aeruginosa coinfection

por Gouda, Ahmed M., Soltan, Mohamed A., Abd-Elghany, Khalid, Sileem, Ashraf E., Elnahas, Hanan M., Ateya, Marwa Abdel-Monem, Elbatreek, Mahmoud H., Darwish, Khaled M., Bogari, Hanin A., Lashkar, Manar O., Aldurdunji, Mohammed M., Elhady, Sameh S., Ahmad, Tarek A., Said, Ahmed Mohamed
Publicado 2023

In Silico Designing of a Multitope Vaccine against Rhizopus microsporus with Potential Activity against Other Mucormycosis Causing Fungi

por Soltan, Mohamed A., Eldeen, Muhammad Alaa, Elbassiouny, Nada, Kamel, Hasnaa L., Abdelraheem, Kareem M., El-Gayyed, Hanaa Abd, Gouda, Ahmed M., Sheha, Mohammed F., Fayad, Eman, Ali, Ola A. Abu, Ghany, Khalid Abd El, El-damasy, Dalia A., Darwish, Khaled M., Elhady, Sameh S., Sileem, Ashraf E.
Publicado 2021

Discovery of novel oxazole-based macrocycles as anti-coronaviral agents targeting SARS-CoV-2 main protease

por Al-Wahaibi, Lamya H., Mostafa, Ahmed, Mostafa, Yaser A., Abou-Ghadir, Ola F., Abdelazeem, Ahmed H., Gouda, Ahmed M., Kutkat, Omnia, Abo Shama, Noura M., Shehata, Mahmoud, Gomaa, Hesham A.M., Abdelrahman, Mostafa H., Mohamed, Fatma A.M., Gu, Xuyuan, Ali, Mohamed A., Trembleau, Laurent, Youssif, Bahaa G.M.
Publicado 2021