Use of Recombinant Adenovirus Vectored Consensus IFN-α to Avert Severe Arenavirus Infection

por Gowen, Brian B., Ennis, Jane, Russell, Andrew, Sefing, Eric J., Wong, Min-Hui, Turner, Jeffrey
Publicado 2011

Full-Exon Resequencing Reveals Toll-Like Receptor Variants Contribute to Human Susceptibility to Tuberculosis Disease

por Ma, Xin, Liu, Yuhua, Gowen, Brian B., Graviss, Edward A., Clark, Andrew G., Musser, James M.
Publicado 2007

Effective Oral Favipiravir (T-705) Therapy Initiated after the Onset of Clinical Disease in a Model of Arenavirus Hemorrhagic Fever

por Mendenhall, Michelle, Russell, Andrew, Smee, Donald F., Hall, Jeffery O., Skirpstunas, Ramona, Furuta, Yousuke, Gowen, Brian B.
Publicado 2011

Single-Dose Intranasal Treatment with DEF201 (Adenovirus Vectored Consensus Interferon) Prevents Lethal Disease Due to Rift Valley Fever Virus Challenge

por Gowen, Brian B., Ennis, Jane, Bailey, Kevin W., Vest, Zachary, Scharton, Dionna, Sefing, Eric J., Turner, Jeffrey D.
Publicado 2014

Type I interferon underlies severe disease associated with Junín virus infection in mice

por Hickerson, Brady T, Sefing, Eric J, Bailey, Kevin W, Van Wettere, Arnaud J, Penichet, Manuel L, Gowen, Brian B
Publicado 2020

An update on the progress of galidesivir (BCX4430), a broad-spectrum antiviral

por Julander, Justin G., Demarest, James F., Taylor, Ray, Gowen, Brian B., Walling, Dennis M., Mathis, Amanda, Babu, Y.S.
Publicado 2021

Rift Valley Fever Virus Infection in Golden Syrian Hamsters

por Scharton, Dionna, Van Wettere, Arnaud J., Bailey, Kevin W., Vest, Zachary, Westover, Jonna B., Siddharthan, Venkatraman, Gowen, Brian B.
Publicado 2015

Assessing changes in vascular permeability in a hamster model of viral hemorrhagic fever

por Gowen, Brian B, Julander, Justin G, London, Nyall R, Wong, Min-Hui, Larson, Deanna, Morrey, John D, Li, Dean Y, Bray, Mike
Publicado 2010

Vascular leak ensues a vigorous proinflammatory cytokine response to Tacaribe arenavirus infection in AG129 mice

por Sefing, Eric J, Wong, Min-Hui, Larson, Deanna P, Hurst, Brett L, Van Wettere, Arnaud J, Schneller, Stewart W, Gowen, Brian B
Publicado 2013

MP-12 virus containing the clone 13 deletion in the NSs gene prevents lethal disease when administered after Rift Valley fever virus infection in hamsters

por Gowen, Brian B., Westover, Jonna B., Sefing, Eric J., Bailey, Kevin W., Nishiyama, Shoko, Wandersee, Luci, Scharton, Dionna, Jung, Kie-Hoon, Ikegami, Tetsuro
Publicado 2015

T-705 (favipiravir) and related compounds: Novel broad-spectrum inhibitors of RNA viral infections

por Furuta, Yousuke, Takahashi, Kazumi, Shiraki, Kimiyasu, Sakamoto, Kenichi, Smee, Donald F., Barnard, Dale L., Gowen, Brian B., Julander, Justin G., Morrey, John D.
Publicado 2009

Pathogenesis of Rift Valley Fever Virus Aerosol Infection in STAT2 Knockout Hamsters

por Hickerson, Brady T., Westover, Jonna B., Van Wettere, Arnaud J., Rigas, Johanna D., Miao, Jinxin, Conrad, Bettina L., Motter, Neil E., Wang, Zhongde, Gowen, Brian B.
Publicado 2018

Treatment of Late Stage Disease in a Model of Arenaviral Hemorrhagic Fever: T-705 Efficacy and Reduced Toxicity Suggests an Alternative to Ribavirin

por Gowen, Brian B., Smee, Donald F., Wong, Min-Hui, Hall, Jeffery O., Jung, Kie-Hoon, Bailey, Kevin W., Stevens, John R., Furuta, Yousuke, Morrey, John D.
Publicado 2008

Galidesivir limits Rift Valley fever virus infection and disease in Syrian golden hamsters

por Westover, Jonna B., Mathis, Amanda, Taylor, Ray, Wandersee, Luci, Bailey, Kevin W., Sefing, Eric J., Hickerson, Brady T., Jung, Kie-Hoon, Sheridan, William P., Gowen, Brian B.
Publicado 2018

Development of a New Tacaribe Arenavirus Infection Model and Its Use to Explore Antiviral Activity of a Novel Aristeromycin Analog

por Gowen, Brian B., Wong, Min-Hui, Larson, Deanna, Ye, Wei, Jung, Kie-Hoon, Sefing, Eric J., Skirpstunas, Ramona, Smee, Donald F., Morrey, John D., Schneller, Stewart W.
Publicado 2010

The broad-spectrum antiviral favipiravir protects guinea pigs from lethal Lassa virus infection post-disease onset

por Safronetz, David, Rosenke, Kyle, Westover, Jonna B., Martellaro, Cynthia, Okumura, Atsushi, Furuta, Yousuke, Geisbert, Joan, Saturday, Greg, Komeno, Takashi, Geisbert, Thomas W., Feldmann, Heinz, Gowen, Brian B.
Publicado 2015

Vascular Leak and Hypercytokinemia Associated with Severe Fever with Thrombocytopenia Syndrome Virus Infection in Mice

por Westover, Jonna B., Hickerson, Brady T., Van Wettere, Arnaud J., Hurst, Brett L., Kurz, Jacqueline P., Dagley, Ashley, Wülfroth, Petra, Komeno, Takashi, Furuta, Yousuke, Steiner, Thomas, Gowen, Brian B.
Publicado 2019

Favipiravir (T-705) Inhibits Junín Virus Infection and Reduces Mortality in a Guinea Pig Model of Argentine Hemorrhagic Fever

por Gowen, Brian B., Juelich, Terry L., Sefing, Eric J., Brasel, Trevor, Smith, Jennifer K., Zhang, Lihong, Tigabu, Bersabeh, Hill, Terence E., Yun, Tatyana, Pietzsch, Colette, Furuta, Yousuke, Freiberg, Alexander N.
Publicado 2013

Use of Favipiravir to Treat Lassa Virus Infection in Macaques

por Rosenke, Kyle, Feldmann, Heinz, Westover, Jonna B., Hanley, Patrick William, Martellaro, Cynthia, Feldmann, Friederike, Saturday, Greg, Lovaglio, Jamie, Scott, Dana P., Furuta, Yousuke, Komeno, Takashi, Gowen, Brian B., Safronetz, David
Publicado 2018

Characterization of a novel STAT 2 knock-out hamster model of Crimean-Congo hemorrhagic fever virus pathogenesis

por Ranadheera, Charlene, Valcourt, Emelissa J., Warner, Bryce M., Poliquin, Guillaume, Rosenke, Kyle, Frost, Kathy, Tierney, Kevin, Saturday, Greg, Miao, Jinxin, Westover, Jonna B., Gowen, Brian B., Booth, Stephanie, Feldmann, Heinz, Wang, Zhongde, Safronetz, David
Publicado 2020