Novel CALM3 mutations in pediatric long QT syndrome patients support a CALM3-specific calmodulinopathy

por Chaix, Marie-A., Koopmann, Tamara T., Goyette, Philippe, Alikashani, Azadeh, Latour, Frédéric, Fatah, Meena, Hamilton, Robert M., Rioux, John D.
Publicado 2016

A transcriptome-based approach to identify functional modules within and across primary human immune cells

por Mola, Saraï, Foisy, Sylvain, Boucher, Gabrielle, Major, François, Beauchamp, Claudine, Karaky, Mohamad, Goyette, Philippe, Lesage, Sylvie, Rioux, John D.
Publicado 2020

Defining the Role of the MHC in Autoimmunity: A Review and Pooled Analysis

por Fernando, Michelle M. A., Stevens, Christine R., Walsh, Emily C., De Jager, Philip L., Goyette, Philippe, Plenge, Robert M., Vyse, Timothy J., Rioux, John D.
Publicado 2008

Prostaglandins and calprotectin are genetically and functionally linked to the Inflammatory Bowel Diseases

por Karaky, Mohamad, Boucher, Gabrielle, Mola, Saraï, Foisy, Sylvain, Beauchamp, Claudine, Rivard, Marie-Eve, Burnette, Melanie, Gosselin, Hugues, Bitton, Alain, Charron, Guy, Goyette, Philippe, Rioux, John D.
Publicado 2022

Effect of Sex and Underlying Disease on the Genetic Association of QT Interval and Sudden Cardiac Death

por Mitchell, Rebecca N., Ashar, Foram N., Jarvelin, Marjo‐Riitta, Froguel, Philippe, Sotoodehnia, Nona, Brody, Jennifer A., Sebert, Sylvain, Huikuri, Heikki, Rioux, John, Goyette, Philippe, Newcomb, Charles E., Junttila, M. Juhani, Arking, Dan E.
Publicado 2019

Functional screen of inflammatory bowel disease genes reveals key epithelial functions

por Ntunzwenimana, Jessy Carol, Boucher, Gabrielle, Paquette, Jean, Gosselin, Hugues, Alikashani, Azadeh, Morin, Nicolas, Beauchamp, Claudine, Thauvette, Louise, Rivard, Marie-Ève, Dupuis, Frédérique, Deschênes, Sonia, Foisy, Sylvain, Latour, Frédéric, Lavallée, Geneviève, Daly, Mark J., Xavier, Ramnik J., Charron, Guy, Goyette, Philippe, Rioux, John D.
Publicado 2021

A Meta-Analysis of Genome-Wide Association Scans Identifies IL18RAP, PTPN2, TAGAP, and PUS10 As Shared Risk Loci for Crohn's Disease and Celiac Disease

por Festen, Eleonora A. M., Goyette, Philippe, Green, Todd, Boucher, Gabrielle, Beauchamp, Claudine, Trynka, Gosia, Dubois, Patrick C., Lagacé, Caroline, Stokkers, Pieter C. F., Hommes, Daan W., Barisani, Donatella, Palmieri, Orazio, Annese, Vito, van Heel, David A., Weersma, Rinse K., Daly, Mark J., Wijmenga, Cisca, Rioux, John D.
Publicado 2011

A Major Histocompatibility Class I Locus Contributes to Multiple Sclerosis Susceptibility Independently from HLA-DRB1*15:01

por Cree, Bruce A. C., Rioux, John D., McCauley, Jacob L., Gourraud, Pierre-Antoine F. D., Goyette, Philippe, McElroy, Joseph, De Jager, Philip, Santaniello, Adam, Vyse, Timothy J., Gregersen, Peter K., Mirel, Daniel, Hafler, David A., Haines, Jonathan L., Pericak-Vance, Margaret A., Compston, Alastair, Sawcer, Stephen J., Oksenberg, Jorge R., Hauser, Stephen L.
Publicado 2010

High density mapping of the MHC identifies a shared role for HLA-DRB1*01:03 in inflammatory bowel diseases and heterozygous advantage in ulcerative colitis

por Goyette, Philippe, Boucher, Gabrielle, Mallon, Dermot, Ellinghaus, Eva, Jostins, Luke, Huang, Hailiang, Ripke, Stephan, Gusareva, Elena S, Annese, Vito, Hauser, Stephen L, Oksenberg, Jorge R, Thomsen, Ingo, Leslie, Stephen, Daly, Mark J, Van Steen, Kristel, Duerr, Richard H, Barrett, Jeffrey C, McGovern, Dermot PB, Schumm, L Philip, Traherne, James A, Carrington, Mary N, Kosmoliaptsis, Vasilis, Karlsen, Tom H, Franke, Andre, Rioux, John D
Publicado 2015

TECRL, a new life‐threatening inherited arrhythmia gene associated with overlapping clinical features of both LQTS and CPVT

por Devalla, Harsha D, Gélinas, Roselle, Aburawi, Elhadi H, Beqqali, Abdelaziz, Goyette, Philippe, Freund, Christian, Chaix, Marie‐A, Tadros, Rafik, Jiang, Hui, Le Béchec, Antony, Monshouwer‐Kloots, Jantine J, Zwetsloot, Tom, Kosmidis, Georgios, Latour, Frédéric, Alikashani, Azadeh, Hoekstra, Maaike, Schlaepfer, Jurg, Mummery, Christine L, Stevenson, Brian, Kutalik, Zoltan, de Vries, Antoine AF, Rivard, Léna, Wilde, Arthur AM, Talajic, Mario, Verkerk, Arie O, Al‐Gazali, Lihadh, Rioux, John D, Bhuiyan, Zahurul A, Passier, Robert
Publicado 2016

Deep Resequencing of GWAS Loci Identifies Rare Variants in CARD9, IL23R and RNF186 That Are Associated with Ulcerative Colitis

por Beaudoin, Mélissa, Goyette, Philippe, Boucher, Gabrielle, Lo, Ken Sin, Rivas, Manuel A., Stevens, Christine, Alikashani, Azadeh, Ladouceur, Martin, Ellinghaus, David, Törkvist, Leif, Goel, Gautam, Lagacé, Caroline, Annese, Vito, Bitton, Alain, Begun, Jakob, Brant, Steve R., Bresso, Francesca, Cho, Judy H., Duerr, Richard H., Halfvarson, Jonas, McGovern, Dermot P. B., Radford-Smith, Graham, Schreiber, Stefan, Schumm, Philip L., Sharma, Yashoda, Silverberg, Mark S., Weersma, Rinse K., D'Amato, Mauro, Vermeire, Severine, Franke, Andre, Lettre, Guillaume, Xavier, Ramnik J., Daly, Mark J., Rioux, John D.
Publicado 2013

Ulcerative colitis loci on chromosomes 1p36 and 12q15 identified by genome-wide association study

por Silverberg, Mark S., Cho, Judy H., Rioux, John D., McGovern, Dermot P.B., Wu, Jing, Annese, Vito, Achkar, Jean-Paul, Goyette, Philippe, Scott, Regan, Xu, Wei, Barmada, M. Michael, Klei, Lambertus, Daly, Mark J., Abraham, Clara, Bayless, Theodore M., Bossa, Fabrizio, Griffiths, Anne M., Ippoliti, Andrew F., Lahaie, Raymond G., Latiano, Anna, Paré, Pierre, Proctor, Deborah D., Regueiro, Miguel D., Steinhart, A. Hillary, Targan, Stephan R., Schumm, L. Philip, Kistner, Emily O., Lee, Annette T., Gregersen, Peter K., Rotter, Jerome I., Brant, Steven R., Taylor, Kent D., Roeder, Kathryn, Duerr, Richard H.
Publicado 2009

Deep resequencing of GWAS loci identifies independent rare variants associated with inflammatory bowel disease

por Rivas, Manuel A., Beaudoin, Melissa, Gardet, Agnes, Stevens, Christine, Sharma, Yashoda, Zhang, Clarence K., Boucher, Gabrielle, Ripke, Stephan, Ellinghaus, David, Burtt, Noel, Fennell, Tim, Kirby, Andrew, Latiano, Anna, Goyette, Philippe, Green, Todd, Halfvarson, Jonas, Haritunians, Talin, Korn, Joshua M., Kuruvilla, Finny, Lagacé, Caroline, Neale, Benjamin, Lo, Ken Sin, Schumm, Phil, Törkvist, Leif, Dubinsky, Marla, Brant, Steven R., Silverberg, Mark, Duerr, Richard H., Altshuler, David, Gabriel, Stacey, Lettre, Guillaume, Franke, Andre, D’Amato, Mauro, McGovern, Dermot P.B., Cho, Judy H., Rioux, John D., Xavier, Ramnik J., Daly, Mark J.
Publicado 2011

Inherited determinants of Crohn's disease and ulcerative colitis phenotypes: a genetic association study

por Cleynen, Isabelle, Boucher, Gabrielle, Jostins, Luke, Schumm, L Philip, Zeissig, Sebastian, Ahmad, Tariq, Andersen, Vibeke, Andrews, Jane M, Annese, Vito, Brand, Stephan, Brant, Steven R, Cho, Judy H, Daly, Mark J, Dubinsky, Marla, Duerr, Richard H, Ferguson, Lynnette R, Franke, Andre, Gearry, Richard B, Goyette, Philippe, Hakonarson, Hakon, Halfvarson, Jonas, Hov, Johannes R, Huang, Hailang, Kennedy, Nicholas A, Kupcinskas, Limas, Lawrance, Ian C, Lee, James C, Satsangi, Jack, Schreiber, Stephan, Théâtre, Emilie, van der Meulen-de Jong, Andrea E, Weersma, Rinse K, Wilson, David C, Parkes, Miles, Vermeire, Severine, Rioux, John D, Mansfield, John, Silverberg, Mark S, Radford-Smith, Graham, McGovern, Dermot P B, Barrett, Jeffrey C, Lees, Charlie W
Publicado 2016

Fine-mapping inflammatory bowel disease loci to single variant resolution

por Huang, Hailiang, Fang, Ming, Jostins, Luke, Mirkov, Maša Umićević, Boucher, Gabrielle, Anderson, Carl A, Andersen, Vibeke, Cleynen, Isabelle, Cortes, Adrian, Crins, François, D'Amato, Mauro, Deffontaine, Valérie, Dimitrieva, Julia, Docampo, Elisa, Elansary, Mahmoud, Farh, Kyle Kai-How, Franke, Andre, Gori, Ann-Stephan, Goyette, Philippe, Halfvarson, Jonas, Haritunians, Talin, Knight, Jo, Lawrance, Ian C, Lees, Charlie W, Louis, Edouard, Mariman, Rob, Meuwissen, Theo, Mni, Myriam, Momozawa, Yukihide, Parkes, Miles, Spain, Sarah L, Théâtre, Emilie, Trynka, Gosia, Satsangi, Jack, van Sommeren, Suzanne, Vermeire, Severine, Xavier, Ramnik J, Weersma, Rinse K, Duerr, Richard H, Mathew, Christopher G, Rioux, John D, McGovern, Dermot PB, Cho, Judy H, Georges, Michel, Daly, Mark J, Barrett, Jeffrey C
Publicado 2017

Erratum: A protein-truncating R179X variant in RNF186 confers protection against ulcerative colitis

por Rivas, Manuel A., Graham, Daniel, Sulem, Patrick, Stevens, Christine, Desch, A. Nicole, Goyette, Philippe, Gudbjartsson, Daniel, Jonsdottir, Ingileif, Thorsteinsdottir, Unnur, Degenhardt, Frauke, Mucha, Sören, Kurki, Mitja I., Li, Dalin, D'Amato, Mauro, Annese, Vito, Vermeire, Severine, Weersma, Rinse K., Halfvarson, Jonas, Paavola-Sakki, Paulina, Lappalainen, Maarit, Lek, Monkol, Cummings, Beryl, Tukiainen, Taru, Haritunians, Talin, Halme, Leena, Koskinen, Lotta L. E., Ananthakrishnan, Ashwin N., Luo, Yang, Heap, Graham A., Visschedijk, Marijn C., MacArthur, Daniel G., Neale, Benjamin M., Ahmad, Tariq, Anderson, Carl A., Brant, Steven R., Duerr, Richard H., Silverberg, Mark S., Cho, Judy H., Palotie, Aarno, Saavalainen, Päivi, Kontula, Kimmo, Färkkilä, Martti, McGovern, Dermot P. B., Franke, Andre, Stefansson, Kari, Rioux, John D., Xavier, Ramnik J., Daly, Mark J.
Publicado 2016

Identification of a Sudden Cardiac Death Susceptibility Locus at 2q24.2 through Genome-Wide Association in European Ancestry Individuals

por Arking, Dan E., Junttila, M. Juhani, Goyette, Philippe, Huertas-Vazquez, Adriana, Eijgelsheim, Mark, Blom, Marieke T., Newton-Cheh, Christopher, Reinier, Kyndaron, Teodorescu, Carmen, Uy-Evanado, Audrey, Carter-Monroe, Naima, Kaikkonen, Kari S., Kortelainen, Marja-Leena, Boucher, Gabrielle, Lagacé, Caroline, Moes, Anna, Zhao, XiaoQing, Kolodgie, Frank, Rivadeneira, Fernando, Hofman, Albert, Witteman, Jacqueline C. M., Uitterlinden, André G., Marsman, Roos F., Pazoki, Raha, Bardai, Abdennasser, Koster, Rudolph W., Dehghan, Abbas, Hwang, Shih-Jen, Bhatnagar, Pallav, Post, Wendy, Hilton, Gina, Prineas, Ronald J., Li, Man, Köttgen, Anna, Ehret, Georg, Boerwinkle, Eric, Coresh, Josef, Kao, W. H. Linda, Psaty, Bruce M., Tomaselli, Gordon F., Sotoodehnia, Nona, Siscovick, David S., Burke, Greg L., Marbán, Eduardo, Spooner, Peter M., Cupples, L. Adrienne, Jui, Jonathan, Gunson, Karen, Kesäniemi, Y. Antero, Wilde, Arthur A. M., Tardif, Jean-Claude, O'Donnell, Christopher J., Bezzina, Connie R., Virmani, Renu, Stricker, Bruno H. C. h., Tan, Hanno L., Albert, Christine M., Chakravarti, Aravinda, Rioux, John D., Huikuri, Heikki V., Chugh, Sumeet S.
Publicado 2011

A protein-truncating R179X variant in RNF186 confers protection against ulcerative colitis

por Rivas, Manuel A., Graham, Daniel, Sulem, Patrick, Stevens, Christine, Desch, A. Nicole, Goyette, Philippe, Gudbjartsson, Daniel, Jonsdottir, Ingileif, Thorsteinsdottir, Unnur, Degenhardt, Frauke, Mucha, Sören, Kurki, Mitja I., Li, Dalin, D'Amato, Mauro, Annese, Vito, Vermeire, Severine, Weersma, Rinse K., Halfvarson, Jonas, Paavola-Sakki, Paulina, Lappalainen, Maarit, Lek, Monkol, Cummings, Beryl, Tukiainen, Taru, Haritunians, Talin, Halme, Leena, Koskinen, Lotta L. E., Ananthakrishnan, Ashwin N., Luo, Yang, Heap, Graham A., Visschedijk, Marijn C., MacArthur, Daniel G., Neale, Benjamin M., Ahmad, Tariq, Anderson, Carl A., Brant, Steven R., Duerr, Richard H., Silverberg, Mark S., Cho, Judy H, Palotie, Aarno, Saavalainen, Päivi, Kontula, Kimmo, Färkkilä, Martti, McGovern, Dermot P. B., Franke, Andre, Stefansson, Kari, Rioux, John D., Xavier, Ramnik J., Daly, Mark J., Barrett, J., de Lane, K., Edwards, C., Hart, A., Hawkey, C., Jostins, L., Kennedy, N., Lamb, C., Lee, J., Lees, C., Mansfield, J., Mathew, C., Mowatt, C., Newman, B., Nimmo, E., Parkes, M., Pollard, M., Prescott, N., Randall, J., Rice, D., Satsangi, J., Simmons, A., Tremelling, M., Uhlig, H., Wilson, D., Abraham, C., Achkar, J. P., Bitton, A., Boucher, G., Croitoru, K., Fleshner, P., Glas, J., Kugathasan, S., Limbergen, J. V., Milgrom, R., Proctor, D., Regueiro, M., Schumm, P. L., Sharma, Y., Stempak, J. M., Targan, S. R., Wang, M. H.
Publicado 2016

Host-microbe interactions have shaped the genetic architecture of inflammatory bowel disease

por Jostins, Luke, Ripke, Stephan, Weersma, Rinse K, Duerr, Richard H, McGovern, Dermot P, Hui, Ken Y, Lee, James C, Schumm, L Philip, Sharma, Yashoda, Anderson, Carl A, Essers, Jonah, Mitrovic, Mitja, Ning, Kaida, Cleynen, Isabelle, Theatre, Emilie, Spain, Sarah L, Raychaudhuri, Soumya, Goyette, Philippe, Wei, Zhi, Abraham, Clara, Achkar, Jean-Paul, Ahmad, Tariq, Amininejad, Leila, Ananthakrishnan, Ashwin N, Andersen, Vibeke, Andrews, Jane M, Baidoo, Leonard, Balschun, Tobias, Bampton, Peter A, Bitton, Alain, Boucher, Gabrielle, Brand, Stephan, Büning, Carsten, Cohain, Ariella, Cichon, Sven, D’Amato, Mauro, De Jong, Dirk, Devaney, Kathy L, Dubinsky, Marla, Edwards, Cathryn, Ellinghaus, David, Ferguson, Lynnette R, Franchimont, Denis, Fransen, Karin, Gearry, Richard, Georges, Michel, Gieger, Christian, Glas, Jürgen, Haritunians, Talin, Hart, Ailsa, Hawkey, Chris, Hedl, Matija, Hu, Xinli, Karlsen, Tom H, Kupcinskas, Limas, Kugathasan, Subra, Latiano, Anna, Laukens, Debby, Lawrance, Ian C, Lees, Charlie W, Louis, Edouard, Mahy, Gillian, Mansfield, John, Morgan, Angharad R, Mowat, Craig, Newman, William, Palmieri, Orazio, Ponsioen, Cyriel Y, Potocnik, Uros, Prescott, Natalie J, Regueiro, Miguel, Rotter, Jerome I, Russell, Richard K, Sanderson, Jeremy D, Sans, Miquel, Satsangi, Jack, Schreiber, Stefan, Simms, Lisa A, Sventoraityte, Jurgita, Targan, Stephan R, Taylor, Kent D, Tremelling, Mark, Verspaget, Hein W, De Vos, Martine, Wijmenga, Cisca, Wilson, David C, Winkelmann, Juliane, Xavier, Ramnik J, Zeissig, Sebastian, Zhang, Bin, Zhang, Clarence K, Zhao, Hongyu, Silverberg, Mark S, Annese, Vito, Hakonarson, Hakon, Brant, Steven R, Radford-Smith, Graham, Mathew, Christopher G, Rioux, John D, Schadt, Eric E, Daly, Mark J, Franke, Andre, Parkes, Miles, Vermeire, Severine, Barrett, Jeffrey C, Cho, Judy H
Publicado 2012

Meta-analysis identifies 29 additional ulcerative colitis risk loci, increasing the number of confirmed associations to 47

por Anderson, Carl A., Boucher, Gabrielle, Lees, Charlie W., Franke, Andre, D’Amato, Mauro, Taylor, Kent D., Lee, James C., Goyette, Philippe, Imielinski, Marcin, Latiano, Anna, Lagacé, Caroline, Scott, Regan, Amininejad, Leila, Bumpstead, Suzannah, Baidoo, Leonard, Baldassano, Robert N., Barclay, Murray, Bayless, Theodore M., Brand, Stephan, Büning, Carsten, Colombel, Jean-Frédéric, Denson, Lee A., De Vos, Martine, Dubinsky, Marla, Edwards, Cathryn, Ellinghaus, David, Fehrmann, Rudolf S.N., Floyd, James A.B., Florin, Tim, Franchimont, Denis, Franke, Lude, Georges, Michel, Glas, Jürgen, Glazer, Nicole L., Guthery, Stephen L., Haritunians, Talin, Hayward, Nicholas K., Hugot, Jean-Pierre, Jobin, Gilles, Laukens, Debby, Lawrance, Ian, Lémann, Marc, Levine, Arie, Libioulle, Cecile, Louis, Edouard, McGovern, Dermot P., Milla, Monica, Montgomery, Grant W., Morley, Katherine I., Mowat, Craig, Ng, Aylwin, Newman, William, Ophoff, Roel A, Papi, Laura, Palmieri, Orazio, Peyrin-Biroulet, Laurent, Panés, Julián, Phillips, Anne, Prescott, Natalie J., Proctor, Deborah D., Roberts, Rebecca, Russell, Richard, Rutgeerts, Paul, Sanderson, Jeremy, Sans, Miquel, Schumm, Philip, Seibold, Frank, Sharma, Yashoda, Simms, Lisa, Seielstad, Mark, Steinhart, A. Hillary, Targan, Stephan R., van den Berg, Leonard H., Vatn, Morten, Verspaget, Hein, Walters, Thomas, Wijmenga, Cisca, Wilson, David C., Westra, Harm-Jan, Xavier, Ramnik J., Zhao, Zhen Z., Ponsioen, Cyriel Y., Andersen, Vibeke, Torkvist, Leif, Gazouli, Maria, Anagnou, Nicholas P., Karlsen, Tom H., Kupcinskas, Limas, Sventoraityte, Jurgita, Mansfield, John C., Kugathasan, Subra, Silverberg, Mark S., Halfvarson, Jonas, Rotter, Jerome I., Mathew, Christopher G., Griffiths, Anne M., Gearry, Richard, Ahmad, Tariq, Brant, Steven R., Chamaillard, Mathias, Satsangi, Jack, Cho, Judy H., Schreiber, Stefan, Daly, Mark J., Barrett, Jeffrey C., Parkes, Miles, Annese, Vito, Hakonarson, Hakon, Radford-Smith, Graham, Duerr, Richard H., Vermeire, Séverine, Weersma, Rinse K., Rioux, John D.
Publicado 2011