Branched-Chain Amino Acids Have Equivalent Effects to Other Essential Amino Acids on Lifespan and Aging-Related Traits in Drosophila

por Juricic, Paula, Grönke, Sebastian, Partridge, Linda
Publicado 2020

A Drosophila Insulin-like Peptide Promotes Growth during Nonfeeding States

por Slaidina, Maija, Delanoue, Rénald, Gronke, Sebastian, Partridge, Linda, Léopold, Pierre
Publicado 2009

Molecular Evolution and Functional Characterization of Drosophila Insulin-Like Peptides

por Grönke, Sebastian, Clarke, David-Francis, Broughton, Susan, Andrews, T. Daniel, Partridge, Linda
Publicado 2010

Aβ(43) is neurotoxic and primes aggregation of Aβ(40) in vivo

por Burnouf, Sylvie, Gorsky, Marianna Karina, Dols, Jacqueline, Grönke, Sebastian, Partridge, Linda
Publicado 2015

Dietary restriction mitigates the age-associated decline in mouse B cell receptor repertoire diversity

por Monzó, Carolina, Gkioni, Lisonia, Beyer, Andreas, Valenzano, Dario Riccardo, Grönke, Sebastian, Partridge, Linda
Publicado 2023

Hepatic gene body hypermethylation is a shared epigenetic signature of murine longevity

por Hahn, Oliver, Stubbs, Thomas M., Reik, Wolf, Grönke, Sebastian, Beyer, Andreas, Partridge, Linda
Publicado 2018

The Role of GCN2 Kinase in Mediating the Effects of Amino Acids on Longevity and Feeding Behaviour in Drosophila

por Srivastava, Anchal, Lu, Jiongming, Gadalla, Dennis Said, Hendrich, Oliver, Grönke, Sebastian, Partridge, Linda
Publicado 2022

Lowered Insulin Signalling Ameliorates Age-Related Sleep Fragmentation in Drosophila

por Metaxakis, Athanasios, Tain, Luke S., Grönke, Sebastian, Hendrich, Oliver, Hinze, Yvonne, Birras, Ulrike, Partridge, Linda
Publicado 2014

Glycine-alanine dipeptide repeats spread rapidly in a repeat length- and age-dependent manner in the fly brain

por Morón-Oset, Javier, Supèr, Tessa, Esser, Jacqueline, Isaacs, Adrian M., Grönke, Sebastian, Partridge, Linda
Publicado 2019

Longevity in response to lowered insulin signaling requires glycine N‐methyltransferase‐dependent spermidine production

por Tain, Luke S., Jain, Chirag, Nespital, Tobias, Froehlich, Jenny, Hinze, Yvonne, Grönke, Sebastian, Partridge, Linda
Publicado 2019

Insulin and TOR signal in parallel through FOXO and S6K to promote epithelial wound healing

por Kakanj, Parisa, Moussian, Bernard, Grönke, Sebastian, Bustos, Victor, Eming, Sabine A., Partridge, Linda, Leptin, Maria
Publicado 2016

Reduced insulin signaling in neurons induces sex-specific health benefits

por Baghdadi, Maarouf, Nespital, Tobias, Mesaros, Andrea, Buschbaum, Sandra, Withers, Dominic J., Grönke, Sebastian, Partridge, Linda
Publicado 2023

Insulin signalling regulates remating in female Drosophila

por Wigby, Stuart, Slack, Cathy, Grönke, Sebastian, Martinez, Pedro, Calboli, Federico C. F., Chapman, Tracey, Partridge, Linda
Publicado 2011

Dual Lipolytic Control of Body Fat Storage and Mobilization in Drosophila

por Grönke, Sebastian, Müller, Günter, Hirsch, Jochen, Fellert, Sonja, Andreou, Alexandra, Haase, Tobias, Jäckle, Herbert, Kühnlein, Ronald P
Publicado 2007

Toxicity of C9orf72-associated dipeptide repeat peptides is modified by commonly used protein tags

por Morón-Oset, Javier, Fischer, Lilly KS, Carcolé, Mireia, Giblin, Ashling, Zhang, Pingze, Isaacs, Adrian M, Grönke, Sebastian, Partridge, Linda
Publicado 2023

Pseudo-acetylation of multiple sites on human Tau proteins alters Tau phosphorylation and microtubule binding, and ameliorates amyloid beta toxicity

por Gorsky, Marianna Karina, Burnouf, Sylvie, Sofola-Adesakin, Oyinkan, Dols, Jacqueline, Augustin, Hrvoje, Weigelt, Carina Marianne, Grönke, Sebastian, Partridge, Linda
Publicado 2017

Mutations of mitochondrial DNA are not major contributors to aging of fruit flies

por Kauppila, Timo E. S., Bratic, Ana, Jensen, Martin Borch, Baggio, Francesca, Partridge, Linda, Jasper, Heinrich, Grönke, Sebastian, Larsson, Nils-Göran
Publicado 2018

An Insulin-Sensitive Circular RNA that Regulates Lifespan in Drosophila

por Weigelt, Carina Marianne, Sehgal, Rohan, Tain, Luke Stephen, Cheng, Jun, Eßer, Jacqueline, Pahl, André, Dieterich, Christoph, Grönke, Sebastian, Partridge, Linda
Publicado 2020

Deletion of endogenous Tau proteins is not detrimental in Drosophila

por Burnouf, Sylvie, Grönke, Sebastian, Augustin, Hrvoje, Dols, Jacqueline, Gorsky, Marianna Karina, Werner, Jennifer, Kerr, Fiona, Alic, Nazif, Martinez, Pedro, Partridge, Linda
Publicado 2016

A triple drug combination targeting components of the nutrient-sensing network maximizes longevity

por Castillo-Quan, Jorge Iván, Tain, Luke S., Kinghorn, Kerri J., Li, Li, Grönke, Sebastian, Hinze, Yvonne, Blackwell, T. Keith, Bjedov, Ivana, Partridge, Linda
Publicado 2019