Astrocyte-Neuron Metabolic Crosstalk in Neurodegeneration: A Mitochondrial Perspective

por Mulica, Patrycja, Grünewald, Anne, Pereira, Sandro L.
Publicado 2021

Mitochondria and Parkinson’s Disease: Clinical, Molecular, and Translational Aspects

por Borsche, Max, Pereira, Sandro L., Klein, Christine, Grünewald, Anne
Publicado 2021

The Contribution of Microglia to Neuroinflammation in Parkinson’s Disease

por Badanjak, Katja, Fixemer, Sonja, Smajić, Semra, Skupin, Alexander, Grünewald, Anne
Publicado 2021

A genome on shaky ground: exploring the impact of mitochondrial DNA integrity on Parkinson’s disease by highlighting the use of cybrid models

por Lang, Martin, Grünewald, Anne, Pramstaller, Peter P., Hicks, Andrew A., Pichler, Irene
Publicado 2022

Benchmarking Low-Frequency Variant Calling With Long-Read Data on Mitochondrial DNA

por Lüth, Theresa, Schaake, Susen, Grünewald, Anne, May, Patrick, Trinh, Joanne, Weissensteiner, Hansi
Publicado 2022

PINK1-Interacting Proteins: Proteomic Analysis of Overexpressed PINK1

por Rakovic, Aleksandar, Grünewald, Anne, Voges, Lisa, Hofmann, Sarah, Orolicki, Slobodanka, Lohmann, Katja, Klein, Christine
Publicado 2011

Lifestyle factors and clinical severity of Parkinson’s disease

por Gabbert, Carolin, König, Inke R., Lüth, Theresa, Kasten, Meike, Grünewald, Anne, Klein, Christine, Trinh, Joanne
Publicado 2023

Mutations in PINK1 and Parkin Impair Ubiquitination of Mitofusins in Human Fibroblasts

por Rakovic, Aleksandar, Grünewald, Anne, Kottwitz, Jan, Brüggemann, Norbert, Pramstaller, Peter P., Lohmann, Katja, Klein, Christine
Publicado 2011

Bioenergetic Consequences of PINK1 Mutations in Parkinson Disease

por Abramov, Andrey Yurevich, Gegg, Matthew, Grunewald, Anne, Wood, Nicholas William, Klein, Christine, Schapira, Anthony Henry Vernon
Publicado 2011

Mitochondrial DNA Depletion in Respiratory Chain–Deficient Parkinson Disease Neurons

por Grünewald, Anne, Rygiel, Karolina A., Hepplewhite, Philippa D., Morris, Christopher M., Picard, Martin, Turnbull, Doug M.
Publicado 2016

PINK1 Protects against Staurosporine-Induced Apoptosis by Interacting with Beclin1 and Impairing Its Pro-Apoptotic Cleavage

por Brunelli, Francesco, Torosantucci, Liliana, Gelmetti, Vania, Franzone, Davide, Grünewald, Anne, Krüger, Rejko, Arena, Giuseppe, Valente, Enza Maria
Publicado 2022

Faithful SGCE imprinting in iPSC-derived cortical neurons: an endogenous cellular model of myoclonus-dystonia

por Grütz, Karen, Seibler, Philip, Weissbach, Anne, Lohmann, Katja, Carlisle, Francesca A., Blake, Derek J., Westenberger, Ana, Klein, Christine, Grünewald, Anne
Publicado 2017

Nanopore Single-Molecule Sequencing for Mitochondrial DNA Methylation Analysis: Investigating Parkin-Associated Parkinsonism as a Proof of Concept

por Lüth, Theresa, Wasner, Kobi, Klein, Christine, Schaake, Susen, Tse, Ronnie, Pereira, Sandro L., Laß, Joshua, Sinkkonen, Lasse, Grünewald, Anne, Trinh, Joanne
Publicado 2021

Midbrain organoids mimic early embryonic neurodevelopment and recapitulate LRRK2-p.Gly2019Ser-associated gene expression

por Zagare, Alise, Barmpa, Kyriaki, Smajic, Semra, Smits, Lisa M., Grzyb, Kamil, Grünewald, Anne, Skupin, Alexander, Nickels, Sarah L., Schwamborn, Jens C.
Publicado 2022

Generation of two induced pluripotent stem cell lines and the corresponding isogenic controls from Parkinson’s disease patients carrying the heterozygous mutations c.1290A > G (p.T...

por Chemla, Axel, Arena, Giuseppe, Saraiva, Claudia, Berenguer-Escuder, Clara, Grossmann, Dajana, Grünewald, Anne, Klein, Christine, Seibler, Philip, Schwamborn, Jens C., Krüger, Rejko
Publicado 2023

A novel immunofluorescent assay to investigate oxidative phosphorylation deficiency in mitochondrial myopathy: understanding mechanisms and improving diagnosis

por Rocha, Mariana C., Grady, John P., Grünewald, Anne, Vincent, Amy, Dobson, Philip F., Taylor, Robert W., Turnbull, Doug M., Rygiel, Karolina A.
Publicado 2015

Coffee, smoking and aspirin are associated with age at onset in idiopathic Parkinson’s disease

por Gabbert, Carolin, König, Inke R., Lüth, Theresa, Kolms, Beke, Kasten, Meike, Vollstedt, Eva-Juliane, Balck, Alexander, Grünewald, Anne, Klein, Christine, Trinh, Joanne
Publicado 2022

Quantitative quadruple-label immunofluorescence of mitochondrial and cytoplasmic proteins in single neurons from human midbrain tissue

por Grünewald, Anne, Lax, Nichola Z., Rocha, Mariana C., Reeve, Amy K., Hepplewhite, Philippa D., A. Rygiel, Karolina, Taylor, Robert W., Turnbull, Doug M.
Publicado 2014

Mitochondrial DNA Deletions Discriminate Affected from Unaffected LRRK2 Mutation Carriers

por Ouzren, Nassima, Delcambre, Sylvie, Ghelfi, Jenny, Seibler, Philip, Farrer, Matthew J., König, Inke R., Aasly, Jan O., Trinh, Joanne, Klein, Christine, Grünewald, Anne
Publicado 2019

Bee Venom and Its Component Apamin as Neuroprotective Agents in a Parkinson Disease Mouse Model

por Alvarez-Fischer, Daniel, Noelker, Carmen, Vulinović, Franca, Grünewald, Anne, Chevarin, Caroline, Klein, Christine, Oertel, Wolfgang H., Hirsch, Etienne C., Michel, Patrick P., Hartmann, Andreas
Publicado 2013