Editorial: Biology-Driven Targeted Therapy of Pediatric Soft-Tissue and Bone Tumors: Current Opportunities and Future Challenges

por Grünewald, Thomas G. P., Fulda, Simone
Publicado 2016

Interaction between somatic mutations and germline variants contributes to clinical heterogeneity in cancer

por Musa, Julian, Grünewald, Thomas G. P.
Publicado 2019

An update on the LIM and SH3 domain protein 1 (LASP1): a versatile structural, signaling, and biomarker protein

por Orth, Martin F., Cazes, Alex, Butt, Elke, Grunewald, Thomas G. P.
Publicado 2014

Anti-oxidative stress response genes: bioinformatic analysis of their expression and relevance in multiple cancers

por Rotblat, Barak, Grunewald, Thomas G. P., Leprivier, Gabriel, Melino, Gerry, Knight, Richard A.
Publicado 2013

LASP1, a Newly Identified Melanocytic Protein with a Possible Role in Melanin Release, but Not in Melanoma Progression

por Vaman V. S., Anjana, Poppe, Heiko, Houben, Roland, Grunewald, Thomas G. P., Goebeler, Matthias, Butt, Elke
Publicado 2015

The LPA1/ZEB1/miR-21-activation pathway regulates metastasis in basal breast cancer

por Sahay, Debashish, Leblanc, Raphael, Grunewald, Thomas G. P., Ambatipudi, Srikant, Ribeiro, Johnny, Clézardin, Philippe, Peyruchaud, Olivier
Publicado 2015

Eukaryotic translation initiation factor 4E binding protein 1 (EIF4EBP1) expression in glioblastoma is driven by ETS1- and MYBL2-dependent transcriptional activation

por Hauffe, Laura, Picard, Daniel, Musa, Julian, Remke, Marc, Grünewald, Thomas G. P., Rotblat, Barak, Reifenberger, Guido, Leprivier, Gabriel
Publicado 2022

The DNA-polymorphism rs849142 is associated with skin toxicity induced by targeted anti-EGFR therapy using cetuximab

por Froelich, Matthias F., Stintzing, Sebastian, Kumbrink, Jörg, Grünewald, Thomas G.P., Mansmann, Ulrich, Heinemann, Volker, Kirchner, Thomas, Jung, Andreas
Publicado 2018

Targeting the undruggable: exploiting neomorphic features of fusion oncoproteins in childhood sarcomas for innovative therapies

por Knott, Maximilian M. L., Hölting, Tilman L. B., Ohmura, Shunya, Kirchner, Thomas, Cidre-Aranaz, Florencia, Grünewald, Thomas G. P.
Publicado 2020

Hypoxia and HIFs in Ewing sarcoma: new perspectives on a multi-facetted relationship

por Ceranski, A. Katharina, Carreño-Gonzalez, Martha J., Ehlers, Anna C., Colombo, Maria Vittoria, Cidre-Aranaz, Florencia, Grünewald, Thomas G. P.
Publicado 2023

Pan-Cancer Analysis of Mitochondria Chaperone-Client Co-Expression Reveals Chaperone Functional Partitioning

por Galai, Geut, Ben-David, Hila, Levin, Liron, Orth, Martin F., Grünewald, Thomas G. P., Pilosof, Shai, Bershtein, Shimon, Rotblat, Barak
Publicado 2020

Proline metabolism supports metastasis formation and could be inhibited to selectively target metastasizing cancer cells

por Elia, Ilaria, Broekaert, Dorien, Christen, Stefan, Boon, Ruben, Radaelli, Enrico, Orth, Martin F., Verfaillie, Catherine, Grünewald, Thomas G. P., Fendt, Sarah-Maria
Publicado 2017

Pappalysin-1 T cell receptor transgenic allo-restricted T cells kill Ewing sarcoma in vitro and in vivo

por Kirschner, Andreas, Thiede, Melanie, Grünewald, Thomas G. P., Alba Rubio, Rebeca, Richter, Günther H. S., Kirchner, Thomas, Busch, Dirk H., Burdach, Stefan, Thiel, Uwe
Publicado 2017

Sclerosing Epithelioid Fibrosarcoma of the Bone: A Case Report of High Resistance to Chemotherapy and a Survey of the Literature

por Grunewald, Thomas G. P., von Luettichau, Irene, Weirich, Gregor, Wawer, Angela, Behrends, Uta, Prodinger, Peter M., Jundt, Gernot, Bielack, Stefan S., Gradinger, Reiner, Burdach, Stefan
Publicado 2010

LASP1 is a novel BCR-ABL substrate and a phosphorylation-dependent binding partner of CRKL in chronic myeloid leukemia

por Frietsch, Jochen J., Kastner, Carolin, Grunewald, Thomas G. P., Schweigel, Hardy, Nollau, Peter, Ziermann, Janine, Clement, Joachim H., La Rosée, Paul, Hochhaus, Andreas, Butt, Elke
Publicado 2014

Lysosome-associated membrane glycoprotein 1 predicts fratricide amongst T cell receptor transgenic CD8(+) T cells directed against tumor-associated antigens

por Kirschner, Andreas, Thiede, Melanie, Blaeschke, Franziska, Richter, Günther H.S., Gerke, Julia S., Baldauf, Michaela C., Grünewald, Thomas G.P., Busch, Dirk H., Burdach, Stefan, Thiel, Uwe
Publicado 2016

Leukemia escape in immune desert: intraocular relapse of pediatric pro-B-ALL during systemic control by CD19-CAR T cells

por Willier, Semjon, Raedler, Johannes, Blaeschke, Franziska, Stenger, Dana, Pazos Escudero, Montserrat, Jurgeleit, Florian, Grünewald, Thomas G P, Binder, Vera, Schmid, Irene, Albert, Michael H, Wolf, Armin, Feuchtinger, Tobias
Publicado 2020

The Transcription Factor FEZF1, a Direct Target of EWSR1-FLI1 in Ewing Sarcoma Cells, Regulates the Expression of Neural-Specific Genes

por García-García, Laura, Fernández-Tabanera, Enrique, Cervera, Saint T., Melero-Fernández de Mera, Raquel M., Josa, Santiago, González-González, Laura, Rodríguez-Martín, Carlos, Grünewald, Thomas G. P., Alonso, Javier
Publicado 2021

Acute stress enhances the expression of neuroprotection- and neurogenesis-associated genes in the hippocampus of a mouse restraint model

por Sannino, Giuseppina, Pasqualini, Lorenza, Ricciardelli, Eugenia, Montilla, Patricia, Soverchia, Laura, Ruggeri, Barbara, Falcinelli, Silvia, Renzi, Alessandra, Ludka, Colleen, Kirchner, Thomas, Grünewald, Thomas G. P., Ciccocioppo, Roberto, Ubaldi, Massimo, Hardiman, Gary
Publicado 2016

YB-1 regulates stress granule formation and tumor progression by translationally activating G3BP1

por Somasekharan, Syam Prakash, El-Naggar, Amal, Leprivier, Gabriel, Cheng, Hongwei, Hajee, Shamil, Grunewald, Thomas G.P., Zhang, Fan, Ng, Tony, Delattre, Olivier, Evdokimova, Valentina, Wang, Yuzhuo, Gleave, Martin, Sorensen, Poul H.
Publicado 2015