Compi: a framework for portable and reproducible pipelines

por López-Fernández, Hugo, Graña-Castro, Osvaldo, Nogueira-Rodríguez, Alba, Reboiro-Jato, Miguel, Glez-Peña, Daniel
Publicado 2021

CREBBP/EP300 bromodomains are critical to sustain the GATA1/MYC regulatory axis in proliferation

por Garcia-Carpizo, Veronica, Ruiz-Llorente, Sergio, Sarmentero, Jacinto, Graña-Castro, Osvaldo, Pisano, David G., Barrero, Maria J.
Publicado 2018

Pseudoalignment tools as an efficient alternative to detect repeated transposable elements in scRNAseq data

por de Villarreal, Jaime Martínez, Kalisz, Mark, Piedrafita, Gabriel, Graña-Castro, Osvaldo, Chondronasiou, Dafni, Serrano, Manuel, Real, Francisco X
Publicado 2022

Lymphatic vessels interact dynamically with the hair follicle stem cell niche during skin regeneration in vivo

por Peña‐Jimenez, Daniel, Fontenete, Silvia, Megias, Diego, Fustero‐Torre, Coral, Graña‐Castro, Osvaldo, Castellana, Donatello, Loewe, Robert, Perez‐Moreno, Mirna
Publicado 2019

Luminal Rank loss decreases cell fitness leading to basal cell bipotency in parous mammary glands

por Rocha, Ana Sofia, Collado-Solé, Alejandro, Graña-Castro, Osvaldo, Redondo-Pedraza, Jaime, Soria-Alcaide, Gonzalo, Cordero, Alex, Santamaría, Patricia G., González-Suárez, Eva
Publicado 2023

Somatic genome editing with the RCAS-TVA-CRISPR-Cas9 system for precision tumor modeling

por Oldrini, Barbara, Curiel-García, Álvaro, Marques, Carolina, Matia, Veronica, Uluçkan, Özge, Graña-Castro, Osvaldo, Torres-Ruiz, Raul, Rodriguez-Perales, Sandra, Huse, Jason T., Squatrito, Massimo
Publicado 2018

TERRA regulate the transcriptional landscape of pluripotent cells through TRF1-dependent recruitment of PRC2

por Marión, Rosa María, Montero, Juan J, López de Silanes, Isabel, Graña-Castro, Osvaldo, Martínez, Paula, Schoeftner, Stefan, Palacios-Fábrega, José Alejandro, Blasco, Maria A
Publicado 2019

Inhibition of Rag GTPase signaling in mice suppresses B cell responses and lymphomagenesis with minimal detrimental trade-offs

por Ortega-Molina, Ana, Lebrero-Fernández, Cristina, Sanz, Alba, Deleyto-Seldas, Nerea, Plata-Gómez, Ana Belén, Menéndez, Camino, Graña-Castro, Osvaldo, Caleiras, Eduardo, Efeyan, Alejo
Publicado 2021

The mTOR pathway is necessary for survival of mice with short telomeres

por Ferrara-Romeo, Iole, Martinez, Paula, Saraswati, Sarita, Whittemore, Kurt, Graña-Castro, Osvaldo, Thelma Poluha, Lydia, Serrano, Rosa, Hernandez-Encinas, Elena, Blanco-Aparicio, Carmen, Maria Flores, Juana, Blasco, Maria A.
Publicado 2020

Detection of novel fusion-transcripts by RNA-Seq in T-cell lymphoblastic lymphoma

por López-Nieva, Pilar, Fernández-Navarro, Pablo, Graña-Castro, Osvaldo, Andrés-León, Eduardo, Santos, Javier, Villa-Morales, María, Cobos-Fernández, María Ángeles, González-Sánchez, Laura, Malumbres, Marcos, Salazar-Roa, María, Fernández-Piqueras, José
Publicado 2019

MicroRNAs Targeting HIF-2α, VEGFR1 and/or VEGFR2 as Potential Predictive Biomarkers for VEGFR Tyrosine Kinase and HIF-2α Inhibitors in Metastatic Clear-Cell Renal Cell Carcinoma

por Kinget, Lisa, Roussel, Eduard, Verbiest, Annelies, Albersen, Maarten, Rodríguez-Antona, Cristina, Graña-Castro, Osvaldo, Inglada-Pérez, Lucía, Zucman-Rossi, Jessica, Couchy, Gabrielle, Job, Sylvie, de Reyniès, Aurélien, Laenen, Annouschka, Baldewijns, Marcella, Beuselinck, Benoit
Publicado 2021

MicroRNA expression profiles in molecular subtypes of clear-cell renal cell carcinoma are associated with clinical outcome and repression of specific mRNA targets

por Verbiest, Annelies, Van Hoef, Vincent, Rodriguez-Antona, Cristina, García-Donas, Jesús, Graña-Castro, Osvaldo, Albersen, Maarten, Baldewijns, Marcella, Laenen, Annouschka, Roussel, Eduard, Schöffski, Patrick, Wozniak, Agnieszka, Caruso, Stefano, Couchy, Gabrielle, Zucman-Rossi, Jessica, Beuselinck, Benoit
Publicado 2020

MicroRNAs Possibly Involved in the Development of Bone Metastasis in Clear-Cell Renal Cell Carcinoma

por Kinget, Lisa, Roussel, Eduard, Lambrechts, Diether, Boeckx, Bram, Vanginderhuysen, Loïc, Albersen, Maarten, Rodríguez-Antona, Cristina, Graña-Castro, Osvaldo, Inglada-Pérez, Lucía, Verbiest, Annelies, Zucman-Rossi, Jessica, Couchy, Gabrielle, Caruso, Stefano, Laenen, Annouschka, Baldewijns, Marcella, Beuselinck, Benoit
Publicado 2021

3D chromatin connectivity underlies replication origin efficiency in mouse embryonic stem cells

por Jodkowska, Karolina, Pancaldi, Vera, Rigau, Maria, Almeida, Ricardo, Fernández-Justel, José M, Graña-Castro, Osvaldo, Rodríguez-Acebes, Sara, Rubio-Camarillo, Miriam, Carrillo-de Santa Pau, Enrique, Pisano, David, Al-Shahrour, Fátima, Valencia, Alfonso, Gómez, María, Méndez, Juan
Publicado 2022

RNA-Seq reveals the existence of a CDKN1C-E2F1-TP53 axis that is altered in human T-cell lymphoblastic lymphomas

por López-Nieva, Pilar, Fernández-Navarro, Pablo, Vaquero-Lorenzo, Concepción, Villa-Morales, María, Graña-Castro, Osvaldo, Cobos-Fernández, María Ángeles, López-Lorenzo, José Luis, Llamas, Pilar, González-Sanchez, Laura, Sastre, Isabel, Pollan, Marina, Malumbres, Marcos, Santos, Javier, Fernández-Piqueras, José
Publicado 2018

Deficient adaptation to centrosome duplication defects in neural progenitors causes microcephaly and subcortical heterotopias

por González-Martínez, José, Cwetsch, Andrzej W., Martínez-Alonso, Diego, López-Sainz, Luis R., Almagro, Jorge, Melati, Anna, Gómez, Jesús, Pérez-Martínez, Manuel, Megías, Diego, Boskovic, Jasminka, Gilabert-Juan, Javier, Graña-Castro, Osvaldo, Pierani, Alessandra, Behrens, Axel, Ortega, Sagrario, Malumbres, Marcos
Publicado 2021

The RNA Polymerase II Factor RPAP1 Is Critical for Mediator-Driven Transcription and Cell Identity

por Lynch, Cian J., Bernad, Raquel, Calvo, Isabel, Nóbrega-Pereira, Sandrina, Ruiz, Sergio, Ibarz, Nuria, Martinez-Val, Ana, Graña-Castro, Osvaldo, Gómez-López, Gonzalo, Andrés-León, Eduardo, Espinosa Angarica, Vladimir, del Sol, Antonio, Ortega, Sagrario, Fernandez-Capetillo, Oscar, Rojo, Enrique, Munoz, Javier, Serrano, Manuel
Publicado 2018

Folliculin-interacting protein FNIP2 impacts on overweight and obesity through a polymorphism in a conserved 3′ untranslated region

por Fernández, Lara P., Deleyto-Seldas, Nerea, Colmenarejo, Gonzalo, Sanz, Alba, Wagner, Sonia, Plata-Gómez, Ana Belén, Gómez-Patiño, Mónica, Molina, Susana, Espinosa-Salinas, Isabel, Aguilar-Aguilar, Elena, Ortega, Sagrario, Graña-Castro, Osvaldo, Loria-Kohen, Viviana, Fernández-Marcos, Pablo J., Efeyan, Alejo, Ramírez de Molina, Ana
Publicado 2022

NKG2D-CAR-transduced natural killer cells efficiently target multiple myeloma

por Leivas, Alejandra, Valeri, Antonio, Córdoba, Laura, García-Ortiz, Almudena, Ortiz, Alejandra, Sánchez-Vega, Laura, Graña-Castro, Osvaldo, Fernández, Lucía, Carreño-Tarragona, Gonzalo, Pérez, Manuel, Megías, Diego, Paciello, María Liz, Sánchez-Pina, Jose, Pérez-Martínez, Antonio, Lee, Dean A., Powell, Daniel J., Río, Paula, Martínez-López, Joaquín
Publicado 2021

miR-203 drives breast cancer cell differentiation

por Martínez-Illescas, Nuria G., Leal, Silvia, González, Patricia, Graña-Castro, Osvaldo, Muñoz-Oliveira, Juan José, Cortés-Peña, Alfonso, Gómez-Gil, María, Vega, Zaira, Neva, Verónica, Romero, Andrea, Quintela-Fandino, Miguel, Ciruelos, Eva, Sanz, Consuelo, Aragón, Sofía, Sotolongo, Leisy, Jiménez, Sara, Caleiras, Eduardo, Mulero, Francisca, Sánchez, Cristina, Malumbres, Marcos, Salazar-Roa, María
Publicado 2023