The Rules of Engagement: Do Microglia Seal the Fate in the Inverse Relation of Glioma and Alzheimer’s Disease?

por Cheray, Mathilde, Stratoulias, Vassilis, Joseph, Bertrand, Grabert, Kathleen
Publicado 2019

Atg7 deficiency in microglia drives an altered transcriptomic profile associated with an impaired neuroinflammatory response

por Friess, Lara, Cheray, Mathilde, Keane, Lily, Grabert, Kathleen, Joseph, Bertrand
Publicado 2021

Defining the Microglia Response during the Time Course of Chronic Neurodegeneration

por Vincenti, James E., Murphy, Lita, Grabert, Kathleen, McColl, Barry W., Cancellotti, Enrico, Freeman, Tom C., Manson, Jean C.
Publicado 2016

Divergent Neuroinflammatory Regulation of Microglial TREM Expression and Involvement of NF-κB

por Owens, Rosie, Grabert, Kathleen, Davies, Claire L., Alfieri, Alessio, Antel, Jack P., Healy, Luke M., McColl, Barry W.
Publicado 2017

Corrigendum: Divergent Neuroinflammatory Regulation of Microglial TREM Expression and Involvement of NF-κB

por Owens, Rosie, Grabert, Kathleen, Davies, Claire L., Alfieri, Alessio, Antel, Jack P., Healy, Luke M., McColl, Barry W.
Publicado 2017

Proteome integral solubility alteration high-throughput proteomics assay identifies Collectin-12 as a non-apoptotic microglial caspase-3 substrate

por Grabert, Kathleen, Engskog-Vlachos, Pinelopi, Škandík, Martin, Vazquez-Cabrera, Guillermo, Murgoci, Adriana-Natalia, Keane, Lily, Gaetani, Massimiliano, Joseph, Bertrand, Cheray, Mathilde
Publicado 2023

Inhibition of microglial EZH2 leads to anti-tumoral effects in pediatric diffuse midline gliomas

por Keane, Lily, Cheray, Mathilde, Saidi, Dalel, Kirby, Caoimhe, Friess, Lara, Gonzalez-Rodriguez, Patricia, Gerdes, Maren Elisabeth, Grabert, Kathleen, McColl, Barry W, Joseph, Bertrand
Publicado 2021

SETD2 transcriptional control of ATG14L/S isoforms regulates autophagosome–lysosome fusion

por González-Rodríguez, Patricia, Delorme-Axford, Elizabeth, Bernard, Amélie, Keane, Lily, Stratoulias, Vassilis, Grabert, Kathleen, Engskog-Vlachos, Pinelopi, Füllgrabe, Jens, Klionsky, Daniel J., Joseph, Bertrand
Publicado 2022

Microglial brain region-dependent diversity and selective regional sensitivities to ageing

por Grabert, Kathleen, Michoel, Tom, Karavolos, Michail H, Clohisey, Sara, Baillie, J Kenneth, Stevens, Mark P, Freeman, Tom C, Summers, Kim M, McColl, Barry W
Publicado 2016

Csf1r-mApple Transgene Expression and Ligand Binding In Vivo Reveal Dynamics of CSF1R Expression within the Mononuclear Phagocyte System

por Hawley, Catherine A., Rojo, Rocio, Raper, Anna, Sauter, Kristin A., Lisowski, Zofia M., Grabert, Kathleen, Bain, Calum C., Davis, Gemma M., Louwe, Pieter A., Ostrowski, Michael C., Hume, David A., Pridans, Clare, Jenkins, Stephen J.
Publicado 2018

A kinase-dead Csf1r mutation associated with adult-onset leukoencephalopathy has a dominant inhibitory impact on CSF1R signalling

por Stables, Jennifer, Green, Emma K., Sehgal, Anuj, Patkar, Omkar L., Keshvari, Sahar, Taylor, Isis, Ashcroft, Maisie E., Grabert, Kathleen, Wollscheid-Lengeling, Evi, Szymkowiak, Stefan, McColl, Barry W., Adamson, Antony, Humphreys, Neil E., Mueller, Werner, Starobova, Hana, Vetter, Irina, Shabestari, Sepideh Kiani, Blurton-Jones, Matthew M., Summers, Kim M., Irvine, Katharine M., Pridans, Clare, Hume, David A.
Publicado 2022

Pleiotropic Impacts of Macrophage and Microglial Deficiency on Development in Rats with Targeted Mutation of the Csf1r Locus

por Pridans, Clare, Raper, Anna, Davis, Gemma M., Alves, Joana, Sauter, Kristin A., Lefevre, Lucas, Regan, Tim, Meek, Stephen, Sutherland, Linda, Thomson, Alison J., Clohisey, Sara, Bush, Stephen J., Rojo, Rocío, Lisowski, Zofia M., Wallace, Robert, Grabert, Kathleen, Upton, Kyle R., Tsai, Yi Ting, Brown, Deborah, Smith, Lee B., Summers, Kim M., Mabbott, Neil A., Piccardo, Pedro, Cheeseman, Michael T., Burdon, Tom, Hume, David A.
Publicado 2018

Correction: Pleiotropic Impacts of Macrophage and Microglial Deficiency on Development in Rats with Targeted Mutation of the Csf1r Locus

por Pridans, Clare, Raper, Anna, Davis, Gemma M., Alves, Joana, Sauter, Kristin A., Lefevre, Lucas, Regan, Tim, Meek, Stephen, Sutherland, Linda, Thomson, Alison J., Clohisey, Sara, Bush, Stephen J., Rojo, Rocío, Lisowski, Zofia M., Wallace, Robert, Grabert, Kathleen, Upton, Kyle R., Tsai, Yi Ting, Brown, Deborah, Smith, Lee B., Summers, Kim M., Mabbott, Neil A., Piccardo, Pedro, Cheeseman, Michael T., Burdon, Tom, Hume, David A.
Publicado 2019

Deletion of a Csf1r enhancer selectively impacts CSF1R expression and development of tissue macrophage populations

por Rojo, Rocío, Raper, Anna, Ozdemir, Derya D., Lefevre, Lucas, Grabert, Kathleen, Wollscheid-Lengeling, Evi, Bradford, Barry, Caruso, Melanie, Gazova, Iveta, Sánchez, Alejandra, Lisowski, Zofia M., Alves, Joana, Molina-Gonzalez, Irene, Davtyan, Hayk, Lodge, Rebecca J., Glover, James D., Wallace, Robert, Munro, David A. D., David, Eyal, Amit, Ido, Miron, Véronique E., Priller, Josef, Jenkins, Stephen J., Hardingham, Giles E., Blurton-Jones, Mathew, Mabbott, Neil A., Summers, Kim M., Hohenstein, Peter, Hume, David A., Pridans, Clare
Publicado 2019

ARG1-expressing microglia show a distinct molecular signature and modulate postnatal development and function of the mouse brain

por Stratoulias, Vassilis, Ruiz, Rocío, Kanatani, Shigeaki, Osman, Ahmed M., Keane, Lily, Armengol, Jose A., Rodríguez-Moreno, Antonio, Murgoci, Adriana-Natalia, García-Domínguez, Irene, Alonso-Bellido, Isabel, González Ibáñez, Fernando, Picard, Katherine, Vázquez-Cabrera, Guillermo, Posada-Pérez, Mercedes, Vernoux, Nathalie, Tejera, Dario, Grabert, Kathleen, Cheray, Mathilde, González-Rodríguez, Patricia, Pérez-Villegas, Eva M., Martínez-Gallego, Irene, Lastra-Romero, Alejandro, Brodin, David, Avila-Cariño, Javier, Cao, Yang, Airavaara, Mikko, Uhlén, Per, Heneka, Michael T., Tremblay, Marie-Ève, Blomgren, Klas, Venero, Jose L., Joseph, Bertrand
Publicado 2023