Off-target effects of the lysosomal acid lipase inhibitors Lalistat-1 and Lalistat-2 on neutral lipid hydrolases

por Bradić, Ivan, Kuentzel, Katharina B., Honeder, Sophie, Grabner, Gernot F., Vujić, Nemanja, Zimmermann, Robert, Birner-Gruenberger, Ruth, Kratky, Dagmar
Publicado 2022

Cooperative lipolytic control of neuronal triacylglycerol by spastic paraplegia-associated enzyme DDHD2 and ATGL

por Hofer, Peter, Grabner, Gernot F., König, Mario, Xie, Hao, Bulfon, Dominik, Ludwig, Anton E., Wolinski, Heimo, Zimmermann, Robert, Zechner, Rudolf, Heier, Christoph
Publicado 2023

Adipose triglyceride lipase is involved in the mobilization of triglyceride and retinoid stores of hepatic stellate cells

por Taschler, Ulrike, Schreiber, Renate, Chitraju, Chandramohan, Grabner, Gernot F., Romauch, Matthias, Wolinski, Heimo, Haemmerle, Guenter, Breinbauer, Rolf, Zechner, Rudolf, Lass, Achim, Zimmermann, Robert
Publicado 2015

Metabolic regulation of the lysosomal cofactor bis(monoacylglycero)phosphate in mice

por Grabner, Gernot F., Fawzy, Nermeen, Schreiber, Renate, Pusch, Lisa M., Bulfon, Dominik, Koefeler, Harald, Eichmann, Thomas O., Lass, Achim, Schweiger, Martina, Marsche, Gunther, Schoiswohl, Gabriele, Taschler, Ulrike, Zimmermann, Robert
Publicado 2020

Development of small molecule inhibitors targeting adipose triglyceride lipase

por Mayer, Nicole, Schweiger, Martina, Romauch, Matthias, Grabner, Gernot F., Eichmann, Thomas O., Fuchs, Elisabeth, Ivkovic, Jakov, Heier, Christoph, Mrak, Irina, Lass, Achim, Höfler, Gerald, Fledelius, Christian, Zechner, Rudolf, Zimmermann, Robert, Breinbauer, Rolf
Publicado 2013

Deletion of Monoglyceride Lipase in Astrocytes Attenuates Lipopolysaccharide-induced Neuroinflammation

por Grabner, Gernot F., Eichmann, Thomas O., Wagner, Bernhard, Gao, Yuanqing, Farzi, Aitak, Taschler, Ulrike, Radner, Franz P. W., Schweiger, Martina, Lass, Achim, Holzer, Peter, Zinser, Erwin, Tschöp, Matthias H., Yi, Chun-Xia, Zimmermann, Robert
Publicado 2016

Cold exposure induces dynamic changes in circulating triacylglycerol species, which is dependent on intracellular lipolysis: A randomized cross-over trial

por Straat, Maaike E., Jurado-Fasoli, Lucas, Ying, Zhixiong, Nahon, Kimberly J., Janssen, Laura G.M., Boon, Mariëtte R., Grabner, Gernot F., Kooijman, Sander, Zimmermann, Robert, Giera, Martin, Rensen, Patrick C.N., Martinez-Tellez, Borja
Publicado 2022

Hypoxia-inducible lipid droplet-associated protein inhibits adipose triglyceride lipase

por Padmanabha Das, Krishna M., Wechselberger, Lisa, Liziczai, Márton, De la Rosa Rodriguez, Montserrat, Grabner, Gernot F., Heier, Christoph, Viertlmayr, Roland, Radler, Claudia, Lichtenegger, Jörg, Zimmermann, Robert, Borst, Jan Willem, Zechner, Rudolf, Kersten, Sander, Oberer, Monika
Publicado 2018

Pharmacological inhibition of adipose triglyceride lipase corrects high-fat diet-induced insulin resistance and hepatosteatosis in mice

por Schweiger, Martina, Romauch, Matthias, Schreiber, Renate, Grabner, Gernot F., Hütter, Sabrina, Kotzbeck, Petra, Benedikt, Pia, Eichmann, Thomas O., Yamada, Sohsuke, Knittelfelder, Oskar, Diwoky, Clemens, Doler, Carina, Mayer, Nicole, De Cecco, Werner, Breinbauer, Rolf, Zimmermann, Robert, Zechner, Rudolf
Publicado 2017

Corrigendum: Pharmacological inhibition of adipose triglyceride lipase corrects high-fat diet-induced insulin resistance and hepatosteatosis in mice

por Schweiger, Martina, Romauch, Matthias, Schreiber, Renate, Grabner, Gernot F, Hütter, Sabrina, Kotzbeck, Petra, Benedikt, Pia, Eichmann, Thomas O, Yamada, Sohsuke, Knittelfelder, Oskar, Diwoky, Clemens, Doler, Carina, Mayer, Nicole, De Cecco, Werner, Breinbauer, Rolf, Zimmermann, Robert, Zechner, Rudolf
Publicado 2017

An immune-sympathetic neuron communication axis guides adipose tissue browning in cancer-associated cachexia

por Xie, Hao, Heier, Christoph, Meng, Xia, Bakiri, Latifa, Pototschnig, Isabella, Tang, Zhiyuan, Schauer, Silvia, Baumgartner, Vanessa J., Grabner, Gernot F., Schabbauer, Gernot, Wolinski, Heimo, Robertson, Graham R., Hoefler, Gerald, Zeng, Wenwen, Wagner, Erwin F., Schweiger, Martina, Zechner, Rudolf
Publicado 2022

Skin Barrier Development Depends on CGI-58 Protein Expression during Late-Stage Keratinocyte Differentiation

por Grond, Susanne, Radner, Franz P.W., Eichmann, Thomas O., Kolb, Dagmar, Grabner, Gernot F., Wolinski, Heimo, Gruber, Robert, Hofer, Peter, Heier, Christoph, Schauer, Silvia, Rülicke, Thomas, Hoefler, Gerald, Schmuth, Matthias, Elias, Peter M., Lass, Achim, Zechner, Rudolf, Haemmerle, Guenter
Publicado 2016

α/β Hydrolase Domain-containing 6 (ABHD6) Degrades the Late Endosomal/Lysosomal Lipid Bis(monoacylglycero)phosphate

por Pribasnig, Maria A., Mrak, Irina, Grabner, Gernot F., Taschler, Ulrike, Knittelfelder, Oskar, Scherz, Barbara, Eichmann, Thomas O., Heier, Christoph, Grumet, Lukas, Kowaliuk, Jakob, Romauch, Matthias, Holler, Stefan, Anderl, Felix, Wolinski, Heimo, Lass, Achim, Breinbauer, Rolf, Marsche, Gunther, Brown, J. Mark, Zimmermann, Robert
Publicado 2015

Fasting-induced G0/G1 switch gene 2 and FGF21 expression in the liver are under regulation of adipose tissue derived fatty acids

por Jaeger, Doris, Schoiswohl, Gabriele, Hofer, Peter, Schreiber, Renate, Schweiger, Martina, Eichmann, Thomas O., Pollak, Nina M., Poecher, Nadja, Grabner, Gernot F., Zierler, Kathrin A., Eder, Sandra, Kolb, Dagmar, Radner, Franz P.W., Preiss-Landl, Karina, Lass, Achim, Zechner, Rudolf, Kershaw, Erin E., Haemmerle, Guenter
Publicado 2015

Dietary sugars, not lipids, drive hypothalamic inflammation

por Gao, Yuanqing, Bielohuby, Maximilian, Fleming, Thomas, Grabner, Gernot F., Foppen, Ewout, Bernhard, Wagner, Guzmán-Ruiz, Mara, Layritz, Clarita, Legutko, Beata, Zinser, Erwin, García-Cáceres, Cristina, Buijs, Ruud M., Woods, Stephen C., Kalsbeek, Andries, Seeley, Randy J., Nawroth, Peter P., Bidlingmaier, Martin, Tschöp, Matthias H., Yi, Chun-Xia
Publicado 2017

Metabolic disease and ABHD6 alter the circulating bis(monoacylglycerol)phosphate profile in mice and humans

por Grabner, Gernot F., Fawzy, Nermeen, Pribasnig, Maria A., Trieb, Markus, Taschler, Ulrike, Holzer, Michael, Schweiger, Martina, Wolinski, Heimo, Kolb, Dagmar, Horvath, Angela, Breinbauer, Rolf, Rülicke, Thomas, Rabl, Roland, Lass, Achim, Stadlbauer, Vanessa, Hutter-Paier, Birgit, Stauber, Rudolf E., Fickert, Peter, Zechner, Rudolf, Marsche, Gunther, Eichmann, Thomas O., Zimmermann, Robert
Publicado 2019

Small-Molecule Inhibitors Targeting Lipolysis in Human Adipocytes

por Grabner, Gernot F., Guttenberger, Nikolaus, Mayer, Nicole, Migglautsch-Sulzer, Anna K., Lembacher-Fadum, Christian, Fawzy, Nermeen, Bulfon, Dominik, Hofer, Peter, Züllig, Thomas, Hartig, Lennart, Kulminskaya, Natalia, Chalhoub, Gabriel, Schratter, Margarita, Radner, Franz P. W., Preiss-Landl, Karina, Masser, Sarah, Lass, Achim, Zechner, Rudolf, Gruber, Karl, Oberer, Monika, Breinbauer, Rolf, Zimmermann, Robert
Publicado 2022