Respiratory chain deficiency in aged spinal motor neurons()

por Rygiel, Karolina A., Grady, John P., Turnbull, Doug M.
Publicado 2014

Triplex real-time PCR–an improved method to detect a wide spectrum of mitochondrial DNA deletions in single cells

por Rygiel, Karolina A., Grady, John P., Taylor, Robert W., Tuppen, Helen A. L., Turnbull, Doug M.
Publicado 2015

Investigating complex I deficiency in Purkinje cells and synapses in patients with mitochondrial disease

por Chrysostomou, Alexia, Grady, John P., Laude, Alex, Taylor, Robert W., Turnbull, Doug M., Lax, Nichola Z.
Publicado 2015

Mitochondrial and inflammatory changes in sporadic inclusion body myositis

por Rygiel, Karolina A., Miller, James, Grady, John P., Rocha, Mariana C., Taylor, Robert W., Turnbull, Doug M.
Publicado 2015

Translocation Breakpoints Preferentially Occur in Euchromatin and Acrocentric Chromosomes

por Lin, Cheng-Yu, Shukla, Ankit, Grady, John P., Fink, J. Lynn, Dray, Eloise, Duijf, Pascal H.G.
Publicado 2018

PTEN deletion drives acute myeloid leukemia resistance to MEK inhibitors

por Smith, Amanda M., Zhang, Christine R.C., Cristino, Alexandre S., Grady, John P., Fink, J. Lynn, Moore, Andrew S.
Publicado 2019

Erratum: PTEN deletion drives acute myeloid leukemia resistance to MEK inhibitors

por Smith, Amanda M., Zhang, Christine R.C., Cristino, Alexandre S., Grady, John P., Fink, J. Lynn, Moore, Andrew S.
Publicado 2020

Clinical Response to Seribantumab, an Anti–Human Epidermal Growth Factor Receptor-3 Immunoglobulin 2 Monoclonal Antibody, in a Patient With Metastatic Pancreatic Ductal Adenocarcin...

por Thavaneswaran, Subotheni, Chan, Wei Yen, Asghari, Ray, Grady, John P., Deegan, Maegan, Jansen, Valerie M., Thomas, David M.
Publicado 2022

Mitochondrial dysfunction within the synapses of substantia nigra neurons in Parkinson’s disease

por Reeve, Amy K., Grady, John P., Cosgrave, Eve M., Bennison, Emma, Chen, Chun, Hepplewhite, Philippa D., Morris, Christopher M.
Publicado 2018

Inherited pathogenic mitochondrial DNA mutations and gastrointestinal stem cell populations

por Su, Tianhong, Grady, John P, Afshar, Sorena, McDonald, Stuart AC, Taylor, Robert W, Turnbull, Doug M, Greaves, Laura C
Publicado 2018

Accurate Measurement of Mitochondrial DNA Deletion Level and Copy Number Differences in Human Skeletal Muscle

por Grady, John P., Murphy, Julie L., Blakely, Emma L., Haller, Ronald G., Taylor, Robert W., Turnbull, Doug M., Tuppen, Helen A. L.
Publicado 2014

A novel immunofluorescent assay to investigate oxidative phosphorylation deficiency in mitochondrial myopathy: understanding mechanisms and improving diagnosis

por Rocha, Mariana C., Grady, John P., Grünewald, Anne, Vincent, Amy, Dobson, Philip F., Taylor, Robert W., Turnbull, Doug M., Rygiel, Karolina A.
Publicado 2015

Mitochondrial dysfunction in myofibrillar myopathy

por Vincent, Amy E., Grady, John P., Rocha, Mariana C., Alston, Charlotte L., Rygiel, Karolina A., Barresi, Rita, Taylor, Robert W., Turnbull, Doug M.
Publicado 2016

Unique quadruple immunofluorescence assay demonstrates mitochondrial respiratory chain dysfunction in osteoblasts of aged and PolgA(−/−) mice

por Dobson, Philip F., Rocha, Mariana C., Grady, John P., Chrysostomou, Alexia, Hipps, Daniel, Watson, Sharon, Greaves, Laura C., Deehan, David J., Turnbull, Doug M.
Publicado 2016

Subclonal evolution in disease progression from MGUS/SMM to multiple myeloma is characterised by clonal stability

por Dutta, Ankit K., Fink, J. Lynn, Grady, John P., Morgan, Gareth J., Mullighan, Charles G., To, Luen B., Hewett, Duncan R., Zannettino, Andrew C. W.
Publicado 2018

Dysferlin mutations and mitochondrial dysfunction

por Vincent, Amy E., Rosa, Hannah S., Alston, Charlotte L., Grady, John P., Rygiel, Karolina A., Rocha, Mariana C., Barresi, Rita, Taylor, Robert W., Turnbull, Doug M.
Publicado 2016

Criteria-based curation of a therapy-focused compendium to support treatment recommendations in precision oncology

por Lin, Frank P., Thavaneswaran, Subotheni, Grady, John P., Ballinger, Mandy, Kansara, Maya, Oakes, Samantha R., Desai, Jayesh, Lee, Chee Khoon, Simes, John, Thomas, David M.
Publicado 2021

Dissecting the neuronal vulnerability underpinning Alpers’ syndrome: a clinical and neuropathological study

por Hayhurst, Hannah, Anagnostou, Maria‐Eleni, Bogle, Helen J., Grady, John P., Taylor, Robert W., Bindoff, Laurence A., McFarland, Robert, Turnbull, Doug M., Lax, Nichola Z.
Publicado 2018

Comparison of Mitochondrial Mutation Spectra in Ageing Human Colonic Epithelium and Disease: Absence of Evidence for Purifying Selection in Somatic Mitochondrial DNA Point Mutation...

por Greaves, Laura C., Elson, Joanna L., Nooteboom, Marco, Grady, John P., Taylor, Geoffrey A., Taylor, Robert W., Mathers, John C., Kirkwood, Thomas B. L., Turnbull, Doug M.
Publicado 2012

Complex mitochondrial DNA rearrangements in individual cells from patients with sporadic inclusion body myositis

por Rygiel, Karolina A., Tuppen, Helen A., Grady, John P., Vincent, Amy, Blakely, Emma L., Reeve, Amy K., Taylor, Robert W., Picard, Martin, Miller, James, Turnbull, Doug M.
Publicado 2016